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Brain Sciences, Volume 13, Issue 7

July 2023 - 146 articles

Cover Story: Non-small cell lung cancer (NSCLC) has a high rate of brain metastasis. The purpose of this study was to assess the differential distribution of brain metastases from primary NSCLC based on mutation status. Brain MRI scans of patients with brain metastases from primary NSCLC were retrospectively analyzed. Brain metastatic tumors were grouped according to the mutation status of their primary NSCLC and the neuroimaging features of these brain metastases were analyzed. A total of 110 patients with 1386 brain metastases from primary NSCLC were included in this study. Our study showed differential spatial distribution of brain metastases in patients with NSCLC according to their mutation status. Information regarding the distribution of brain metastases is clinically relevant as it could be helpful to guide treatment planning for targeted therapy, and for predicting prognosis. View this paper
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Articles (146)

  • Article
  • Open Access
9 Citations
2,150 Views
18 Pages

Endoscopic Endonasal Transplanum–Transtuberculum Approach for Pituitary Adenomas/PitNET: 25 Years of Experience

  • Alessandro Carretta,
  • Matteo Zoli,
  • Federica Guaraldi,
  • Giacomo Sollini,
  • Arianna Rustici,
  • Sofia Asioli,
  • Marco Faustini-Fustini,
  • Ernesto Pasquini and
  • Diego Mazzatenta

The role of the endoscopic transplanum–transtuberculum approach (ETTA) in the treatment of pituitary adenomas/PitNETs (PAs) is sparsely analyzed in the literature, and its use is still debated in the current practice. The aim of this study was...

  • Article
  • Open Access
6 Citations
2,315 Views
14 Pages

Evolution of Cognitive Impairments in Treatment-Resistant Depression: Results from the Longitudinal French Centers of Expertise for Treatment-Resistant Depression (FACE-DR) Cohort

  • Alexis Vancappel,
  • Yecodji Dansou,
  • Ophelia Godin,
  • Emmanuel Haffen,
  • Antoine Yrondi,
  • Florian Stephan,
  • Raphaelle Marie Richieri,
  • Fanny Molière,
  • Jérôme Holtzmann and
  • Mathilde Horn
  • + 25 authors

Previous studies set out profound cognitive impairments in subjects with treatment-resistant depression (TRD). However, little is known about the course of such alterations depending on levels of improvement in those patients followed longitudinally....

  • Article
  • Open Access
10 Citations
4,636 Views
16 Pages

Background and Objective: Dietary constituents may affect the progression of Parkinson’s disease (PD). This study aimed to assess the contribution of dietary intake of vitamins and minerals to the severity, motor and non-motor symptoms, and ris...

  • Article
  • Open Access
2 Citations
3,240 Views
14 Pages

Cognitive–Affective Risk Factors of Female Intimate Partner Violence Victimization: The Role of Early Maladaptive Schemas and Strategic Emotional Intelligence

  • Klaudia Sójta,
  • Aleksandra Margulska,
  • Wioletta Jóźwiak-Majchrzak,
  • Anna Grażka,
  • Karolina Grzelczak and
  • Dominik Strzelecki

(1) Background: Intimate partner violence (IPV) is a pervasive and destructive phenomenon. There is a need for an integrated and comprehensive approach to IPV in order to align prevention, support and treatment. Still little is known about the cognit...

  • Review
  • Open Access
2 Citations
3,147 Views
10 Pages

Current Knowledge about Headaches Attributed to Ischemic Stroke: Changes from Structure to Function

  • Xinxin Xie,
  • Yi Zhang,
  • Qianqian Kong,
  • Hao Huang,
  • Zhiyuan Yu,
  • Xiang Luo and
  • Wensheng Qu

Headaches are common after ischemic stroke (IS). Unlike primary headaches, headaches attributed to IS have specific clinical features. This review describes the epidemiology, clinical characteristics, risk factors, and influence of IS headaches. Prev...

  • Review
  • Open Access
15 Citations
6,475 Views
17 Pages

Autism Spectrum, Hikikomori Syndrome and Internet Gaming Disorder: Is There a Link?

  • Liliana Dell’Osso,
  • Giulia Amatori,
  • Dario Muti,
  • Federico Giovannoni,
  • Francesca Parri,
  • Miriam Violi,
  • Ivan Mirko Cremone and
  • Barbara Carpita

The aim of this study is to review the available literature investigating the relationship between hikikomori, a pathological condition characterized by severe social withdrawal or isolation, autism spectrum disorder (ASD) and Internet gaming disorde...

  • Article
  • Open Access
2,825 Views
33 Pages

Metallothionein I/II Expression and Metal Ion Levels in Correlation with Amyloid Beta Deposits in the Aged Feline Brain

  • Emmanouela P. Apostolopoulou,
  • Nikolaos Raikos,
  • Ioannis Vlemmas,
  • Efstratios Michaelidis and
  • Georgia D. Brellou

Brain aging has been correlated with high metallothionein I-II (MT-I/II) expression, iron and zinc dyshomeostasis, and Aβ deposition in humans and experimental animals. In the present study, iron and zinc accumulation, the expression of MT-I/II...

  • Article
  • Open Access
1 Citations
2,995 Views
11 Pages

Remote Assessment of Parkinson’s Disease Patients Amidst the COVID-19 Lockdown in Mexico

  • Rodrigo León-García,
  • Emmanuel Ortega-Robles and
  • Oscar Arias-Carrión

The COVID-19 pandemic introduced unprecedented challenges in managing patients with Parkinson’s disease (PD) due to disruptions in healthcare services and the need for social distancing. Understanding the effects of COVID-19 on PD symptoms is c...

  • Article
  • Open Access
1 Citations
3,440 Views
20 Pages

The Role of the Dorsolateral Prefrontal Cortex in the Production and Comprehension of Phonologically and Semantically Related Words

  • Lindsay K. Butler,
  • Meredith Pecukonis,
  • De’Ja Rogers,
  • David A. Boas,
  • Helen Tager-Flusberg and
  • Meryem A. Yücel

Previous studies suggest that producing and comprehending semantically related words relies on inhibitory control over competitive lexical selection which results in the recruitment of the left inferior frontal gyrus (IFG). Few studies, however, have...

  • Article
  • Open Access
15 Citations
4,387 Views
15 Pages

Does Therapeutic Exercise Support Improvement in Cognitive Function and Instrumental Activities of Daily Living in Patients with Mild Alzheimer’s Disease? A Randomized Controlled Trial

  • Vasileios Papatsimpas,
  • Sotiria Vrouva,
  • George Papathanasiou,
  • Marianna Papadopoulou,
  • Christina Bouzineki,
  • Sophia Kanellopoulou,
  • Dimitra Moutafi and
  • Daphne Bakalidou

This randomized controlled trial aims to investigate the effect of 12 weeks of therapeutic exercise on cognitive function and daily activities in patients with mild Alzheimer’s disease (AD). A total of 171 patients with mild AD from the Amarous...

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Brain Sci. - ISSN 2076-3425Creative Common CC BY license