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Pathogens, Volume 14, Issue 5

May 2025 - 111 articles

Cover Story: This pilot study aimed to assess a novel experimental model of Bartonella henselae, an important zoonotic pathogen. Six ferrets were divided into a control group and two intradermally inoculated infection groups (low and high dose) and then monitored over 7 weeks before being euthanized. Minimal transient clinical signs and laboratory abnormalities developed in inoculated ferrets. The high-dose group seroconverted to B. henselae antigen within two weeks, maintaining elevated titers throughout the study. Histopathological examination revealed inflammatory lesions in the liver parenchyma, heart, and brain of inoculated ferrets; similar lesions were not observed the two control ferrets. Ferrets may serve as a promising model for investigating the pathogenesis, diagnosis, treatment, and prevention of B. henselae. View this paper
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Articles (111)

  • Article
  • Open Access
1,780 Views
15 Pages

Red Fox (Vulpes vulpes) and Wolf (Canis lupus) as a Reservoir of Cryptosporidium spp. and Giardia intestinalis in Poland

  • Dorota Dwużnik-Szarek,
  • Ewa Julia Mierzejewska,
  • Korneliusz Kurek,
  • Małgorzata Krokowska-Paluszak,
  • Patrycja Opalińska,
  • Łukasz Stańczak,
  • Grzegorz Górecki and
  • Anna Bajer

Infections with zoonotic pathogens have received increasing attention in recent years, as reflected in the literature of both veterinary and human medicine. Cryptosporidium and Giardia are recognised as the principal causes of waterborne outbreaks wo...

  • Article
  • Open Access
1 Citations
1,461 Views
12 Pages

High Prevalence and Genetic Heterogeneity of Anaplasma marginale in Smallholder Bovine Populations of Pakistan, and Its Implications

  • Abdul Ghafar,
  • Waseem Shaukat,
  • Muhammad Waqas,
  • Charles G. Gauci,
  • Robin B. Gasser and
  • Abdul Jabbar

Bovine anaplasmosis, caused by Anaplasma marginale, is a major tick-borne disease in tropical and subtropical regions of the world, leading to significant production losses. Prolonged convalescence periods are common and surviving animals often becom...

  • Article
  • Open Access
1,236 Views
15 Pages

Improvement of Cryopreservation and Production of Attenuated Babesia Parasites to Prevent Bovine Babesiosis

  • Carmen Rojas-Martínez,
  • José J. Lira-Amaya,
  • Massaro W. Ueti,
  • Roberto O. Castañeda-Arriola,
  • Julio V. Figueroa Millán and
  • Jesús A. Álvarez Martínez

This study evaluated the effects of various concentrations of PVP-40 on the in vitro cryopreservation and recovery of Babesia bovis and Babesia bigemina. We also assessed a reduced dose of attenuated Babesia strains to determine its efficacy in preve...

  • Review
  • Open Access
10 Citations
4,174 Views
29 Pages

Antimicrobial Resistant Staphylococcus spp., Escherichia coli, and Salmonella spp. in Food Handlers: A Global Review of Persistence, Transmission, and Mitigation Challenges

  • Gustavo Guimarães Fernandes Viana,
  • Marita Vedovelli Cardozo,
  • Juliano Gonçalves Pereira and
  • Gabriel Augusto Marques Rossi

Antimicrobial resistance in foodborne pathogens represents a critical global health challenge, with food handlers serving as key contributors in their transmission. This comprehensive review synthesizes evidence on the prevalence, transmission dynami...

  • Article
  • Open Access
1 Citations
2,097 Views
14 Pages

Bacterial Acute Otitis Media Complicated with Otorrhea in a Children’s Hospital in the Era of Pneumococcal Conjugate Vaccines

  • Irene Tzovara,
  • Anastasios Doudoulakakis,
  • Georgios Kalogeras,
  • Emmanouil Koutouzis,
  • Charilaos Dellis,
  • Sophia Pasparakis,
  • Marietta Charakida,
  • Evangelia Lebessi,
  • Elisavet Bozavoutoglou and
  • Michael Tsakanikos
  • + 2 authors

Acute otitis media (AOM) is a common disease among children and can be complicated by otorrhea (AOMO). In 2010, the 13-valent Pneumococcal Conjugate Vaccine (PCV13) replaced the 7-valent vaccine (PCV7) in Greece. We aimed to describe the microbiologi...

  • Article
  • Open Access
1 Citations
1,592 Views
17 Pages

Repellent Activity of DEET Combined with Botanical Compounds Against Amblyomma sculptum Nymphs: Laboratory and Field Evaluations

  • Mayara Macêdo Barrozo,
  • Haile Dean Figueiredo Chagas,
  • Gabrielly Bernardes Rodrigues Damaceno,
  • Emilly Faria Santos,
  • Rafael Assunção Carvalho,
  • Isabela Santos Silva,
  • Francisca Letícia Vale,
  • Lainny Jordana Martins Pereira e Sousa,
  • Hermes Ribeiro Luz and
  • Lorena Lopes Ferreira
  • + 1 author

This study evaluated the repellent activity of DEET, eugenol, methyl eugenol, 1,8-cineole, and their combinations against Amblyomma sculptum nymphs through laboratory and field tests. Initially, the botanical compounds were tested individually in Pet...

  • Article
  • Open Access
1 Citations
3,296 Views
17 Pages

Acute Respiratory and Influenza Viruses Circulating in Kazakhstan During 2018–2024

  • Tatyana Glebova,
  • Nailya Klivleyeva,
  • Assem Baimukhametova,
  • Galina Lukmanova,
  • Nurbol Saktaganov,
  • Nuray Ongarbayeva,
  • Baiken Baimakhanova,
  • Gulmira Kassymova,
  • Madisha Sagatova and
  • Almagul Rachimbayeva
  • + 4 authors

Respiratory tract infections cause serious morbidity and mortality and are a major public health problem. The objective of our study was detection of the prevalence of viral respiratory diseases in the territory of Kazakhstan during the epidemic peri...

  • Review
  • Open Access
8 Citations
4,918 Views
16 Pages

Methods of Controlling Microbial Contamination of Food

  • Renata Urban-Chmiel,
  • Jacek Osek and
  • Kinga Wieczorek

The rapid growth of world population and increase in living standards have led to an increase in the demand for high-quality, safe food. The Food and Agriculture Organization of the United Nations (FAO) estimates that by 2050 the demand for food will...

  • Article
  • Open Access
2 Citations
1,537 Views
17 Pages

Validation of a High-Throughput Microfluidic Real-Time PCR for the Detection of Vector-Borne Agents in Wild Birds from the Brazilian Pantanal

  • Amir Salvador Alabí Córdova,
  • João Batista Pinho,
  • Amanda Garcia Pereira,
  • Clémence Galon,
  • Tiago Valadares Ferreira,
  • Lorena Freitas das Neves,
  • Gabrielly de Oliveira Lopes,
  • Rosangela Zacarias Machado,
  • Sara Moutailler and
  • Marcos Rogério André

Despite numerous studies on haemosporidians in wild birds from Brazil, the presence of other vector-borne agents (VBA) such as Anaplasma spp., Bartonella spp., and Onchocercidae filariids in avian hosts remains largely unknown. The low occurrence of...

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Pathogens - ISSN 2076-0817