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Journal of Personalized Medicine, Volume 11, Issue 12

December 2021 - 149 articles

Cover Story: A person high in neuroticism is more likely to experience anxiety, stress, worry, fear, anger, and depression. It is known that gut microbiota can influence personality and mental disorders, including stress, anxiety, and depression, through the gut–brain axis. Here, we investigated correlations between the subfacets of neuroticism and gut microbiota using the Revised NEO Personality Inventory and the 16S rRNA gene sequencing data of 784 Korean adults. Our findings will contribute to uncovering the potential link between gut microbiota and neuroticism, and the elucidation of the correlations of the microbiome–gut–brain axis with behavioral changes and psychiatric cases in the general population. View this paper
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Articles (149)

  • Article
  • Open Access
2 Citations
3,087 Views
15 Pages

Precision Medicine in Aortic Anastomosis: A Numerical and Experimental Study of a Novel Double-Sided Needle

  • Danae G. Manolesou,
  • Georgia Korompili,
  • Dimitris Davazoglou,
  • Andreas M. Lazaris,
  • Dimitrios Schizas,
  • Despina Sanoudou,
  • Theodore Liakakos,
  • Constantinos Tsioufis and
  • Theodore G. Papaioannou

20 December 2021

Background: Hand-sewn anastomosis is a crucial part of aortic reconstruction surgery and significantly affects its outcome. The present study presents a novel, bidirectional surgical needle aimed to improve aortic anastomosis in terms of speed and ea...

  • Article
  • Open Access
5 Citations
3,779 Views
15 Pages

Risk of Dementia in Patients Who Underwent Surgery under Neuraxial Anesthesia: A Nationwide Cohort Study

  • Young-Suk Kwon,
  • Jae-Jun Lee,
  • Sang-Hwa Lee,
  • Chulho Kim,
  • Hyunjae Yu,
  • Jong-Hee Sohn and
  • Dong-Kyu Kim

20 December 2021

The incidence of dementia in patients with surgery under neuraxial anesthesia and the possibility of surgery under neuraxial anesthesia as a risk factor for dementia were investigated. We performed a retrospective matched cohort study with nationwide...

  • Article
  • Open Access
11 Citations
3,576 Views
13 Pages

Assessment of Sleep among Patients with Chronic Liver Disease: Association with Quality of Life

  • Oana-Mihaela Plotogea,
  • Gina Gheorghe,
  • Madalina Stan-Ilie,
  • Gabriel Constantinescu,
  • Nicolae Bacalbasa,
  • Simona Bungau and
  • Camelia Cristina Diaconu

20 December 2021

The present study aims to assess the sleep characteristics and health-related quality of life (HRQOL) among patients with chronic liver diseases (CLDs), as well as the relationship between them. We conducted a prospective cross-sectional study, over...

  • Article
  • Open Access
7 Citations
3,731 Views
13 Pages

Multiparametric Ultrasound Approach Using a Tree-Based Decision Classifier for Inconclusive Focal Liver Lesions Evaluated by Contrast Enhanced Ultrasound

  • Tudor Voicu Moga,
  • Ciprian David,
  • Alina Popescu,
  • Raluca Lupusoru,
  • Darius Heredea,
  • Ana M. Ghiuchici,
  • Camelia Foncea,
  • Adrian Burdan,
  • Roxana Sirli and
  • Mirela Danilă
  • + 3 authors

20 December 2021

Background: Multiparametric ultrasound (MPUS) is a concept whereby the examiner is encouraged to use the latest features of an ultrasound machine. The aim of this study was to reanalyze inconclusive focal liver lesions (FLLs) that had been analyzed v...

  • Review
  • Open Access
1 Citations
2,807 Views
18 Pages

Equity or Equality? Which Approach Brings More Satisfaction in a Kidney-Exchange Chain?

  • Arian Hosseinzadeh,
  • Mehdi Najafi,
  • Wisit Cheungpasitporn,
  • Charat Thongprayoon and
  • Mahdi Fathi

18 December 2021

In United States (U.S.), government-funded organizations, such as NLDAC, reimburse travel and subsistence expenses incurred during living-organ donation process. However, in Iran, there is a non-governmental organization called Iranian Kidney Foundat...

  • Feature Paper
  • Article
  • Open Access
1 Citations
3,160 Views
14 Pages

Prognostic Value of Histone Modifying Enzyme EZH2 in RCHOP-Treated Diffuse Large B-Cell Lymphoma and High Grade B-Cell Lymphoma

  • Sara Petronilho,
  • José Pedro Sequeira,
  • Sofia Paulino,
  • Paula Lopes,
  • Susana Lisboa,
  • Sérgio Chacim,
  • João Lobo,
  • Manuel Teixeira,
  • Carmen Jerónimo and
  • Rui Henrique

18 December 2021

Background: DLBCL represent a heterogeneous group of aggressive diseases. High grade B-cell lymphomas (HGBCL) were recently individualized from DLBCL as a discrete diagnostic entity due to their worse prognosis. Currently, although most patients are...

  • Article
  • Open Access
7 Citations
3,662 Views
14 Pages

Does COVID-19 Clinical Status Associate with Outcome Severity? An Unsupervised Machine Learning Approach for Knowledge Extraction

  • Eleni Karlafti,
  • Athanasios Anagnostis,
  • Evangelia Kotzakioulafi,
  • Michaela Chrysanthi Vittoraki,
  • Ariadni Eufraimidou,
  • Kristine Kasarjyan,
  • Katerina Eufraimidou,
  • Georgia Dimitriadou,
  • Chrisovalantis Kakanis and
  • Michail Anthopoulos
  • + 3 authors

17 December 2021

Since the beginning of the COVID-19 pandemic, 195 million people have been infected and 4.2 million have died from the disease or its side effects. Physicians, healthcare scientists and medical staff continuously try to deal with overloaded hospital...

  • Article
  • Open Access
6 Citations
3,569 Views
13 Pages

A Network-Based Analysis of Disease Complication Associations for Obstetric Disorders in the UK Biobank

  • Vivek Sriram,
  • Yonghyun Nam,
  • Manu Shivakumar,
  • Anurag Verma,
  • Sang-Hyuk Jung,
  • Seung Mi Lee and
  • Dokyoon Kim

17 December 2021

Background: Recent studies have found that women with obstetric disorders are at increased risk for a variety of long-term complications. However, the underlying pathophysiology of these connections remains undetermined. A network-based view incorpor...

  • Article
  • Open Access
3 Citations
3,532 Views
12 Pages

Gut Microbiota Composition across Normal Range Prostate-Specific Antigen Levels

  • Han-Na Kim,
  • Jae-Heon Kim,
  • Yoosoo Chang,
  • Dongmin Yang,
  • Hyung-Lae Kim and
  • Seungho Ryu

17 December 2021

Animal studies have shown the interaction between androgens and the gut microbiome directly and indirectly; however, limited evidence from human studies is available. To evaluate the association between prostate-specific antigen (PSA) levels within t...

  • Article
  • Open Access
9 Citations
3,757 Views
12 Pages

Association of Polymorphisms in Plasminogen Activator Inhibitor-1 (PAI-1), Tissue Plasminogen Activator (tPA), and Renin (REN) with Recurrent Pregnancy Loss in Korean Women

  • Hee Young Cho,
  • Han Sung Park,
  • Eun Hee Ahn,
  • Eun Ju Ko,
  • Hyeon Woo Park,
  • Young Ran Kim,
  • Ji Hyang Kim,
  • Woo Sik Lee and
  • Nam Keun Kim

16 December 2021

Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy losses prior to 20 weeks of gestational age. Various factors, including immune dysfunction, endocrine disorders, coagulation abnormality, and genetic disorders influence R...

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J. Pers. Med. - ISSN 2075-4426