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Diagnostics, Volume 14, Issue 23

2024 December-1 - 160 articles

Cover Story: Background: The study examines Diffusion Tensor Imaging’s (DTI's) role in predicting neoadjuvant chemo-response in locally advanced breast cancer. Methods: A DTI-MRI sequence, evaluating water diffusion along tissue structures, was performed before and after two chemo cycles. Results: We found a significant correlation between changes in specific DTI parameters (e.g., λ2, FA, RA) and pathological response, suggesting DTI as a sensitive marker for early chemo-response. Notably, 12-direction DTI may have better diagnostic accuracy than 6-direction DTI. The percentage change in FA demonstrated a strong ability to predict pathological complete response (pCR) with high sensitivity. Conclusions: DTI may assess chemotherapy efficacy as a non-invasive tool, but larger studies with standardized protocols are needed to confirm its clinical utility. View this paper
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Articles (160)

  • Systematic Review
  • Open Access
4 Citations
3,213 Views
35 Pages

Comprehensive Insights into Artificial Intelligence for Dental Lesion Detection: A Systematic Review

  • Kubra Demir,
  • Ozlem Sokmen,
  • Isil Karabey Aksakalli and
  • Kubra Torenek-Agirman

9 December 2024

Background/Objectives: The growing demand for artificial intelligence (AI) in healthcare is driven by the need for more robust and automated diagnostic systems. These methods not only provide accurate diagnoses but also promise to enhance operational...

  • Interesting Images
  • Open Access
1,610 Views
3 Pages

9 December 2024

Bartonella henselae is a Gram-negative bacillus, mainly parasitizing on cats. When a child is scratched by a cat, they may present with the disease symptoms including regional lymphadenopathy, malaise, fever, and splenomegaly, which is known as cat-s...

  • Article
  • Open Access
1,983 Views
15 Pages

9 December 2024

Background/Objectives: The automatic left ventricle segmentation in transesophageal echocardiography (TEE) is of significant importance. In this paper, we constructed a large-scale TEE apical four-chamber view (A4CV) image dataset and proposed an aut...

  • Systematic Review
  • Open Access
2 Citations
4,886 Views
21 Pages

Systematic Review and Meta-Analysis of Internal Jugular Vein Variants and Their Relationship to Clinical Implications in the Head and Neck

  • Pablo Nova-Baeza,
  • Juan José Valenzuela-Fuenzalida,
  • Rocio Valdivia-Arroyo,
  • Emelyn Sofia Becerra-Rodríguez,
  • Catalina Escalona-Manzo,
  • Yesica Tatiana Castaño-Gallego,
  • Ricardo Miguel Luque-Bernal,
  • Gustavo Oyanedel-Amaro,
  • Alejandra Suazo-Santibáñez and
  • Héctor Gutiérrez-Espinoza
  • + 3 authors

9 December 2024

Background: The internal jugular vein (IJV) is a vascular structure that is responsible for the venous drainage of both the head and neck and is commonly found posterior to the internal carotid artery and adjacent to cervical lymph nodes or nerve str...

  • Systematic Review
  • Open Access
1,431 Views
12 Pages

Definitions of Incidental [18F]FDG PET/CT Findings in the Literature: A Systematic Review and Definition Proposal

  • Jacob Pilegaard Mølstrøm,
  • Natascha Lange,
  • Manan Pareek,
  • Anders Thomassen,
  • Anne Lerberg Nielsen,
  • Poul Flemming Høilund-Carlsen,
  • Christian Godballe and
  • Max Rohde

9 December 2024

Objectives: The objectives of this study were (1) to systematically review the currently used definitions of incidental 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography findings (IPFs) in the literature and (2) to prop...

  • Article
  • Open Access
4 Citations
2,427 Views
40 Pages

Machine and Deep Learning Models for Hypoxemia Severity Triage in CBRNE Emergencies

  • Santino Nanini,
  • Mariem Abid,
  • Yassir Mamouni,
  • Arnaud Wiedemann,
  • Philippe Jouvet and
  • Stephane Bourassa

8 December 2024

Background/Objectives: This study develops machine learning (ML) models to predict hypoxemia severity during emergency triage, particularly in Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) scenarios, using physiological data from...

  • Article
  • Open Access
3 Citations
2,135 Views
12 Pages

Validation of Artificial Intelligence Computer-Aided Detection of Colonic Neoplasm in Colonoscopy

  • Hannah Lee,
  • Jun-Won Chung,
  • Kyoung Oh Kim,
  • Kwang An Kwon,
  • Jung Ho Kim,
  • Sung-Cheol Yun,
  • Sung Woo Jung,
  • Ahmad Sheeraz,
  • Yeong Jun Yoon and
  • Mohd Azzam Kayasseh
  • + 1 author

8 December 2024

Background/Objectives: Controlling colonoscopic quality is important in the detection of colon polyps during colonoscopy as it reduces the overall long-term colorectal cancer risk. Artificial intelligence has recently been introduced in various medic...

  • Article
  • Open Access
4 Citations
2,450 Views
20 Pages

A Comparative Study of Decoders for Liver and Tumor Segmentation Using a Self-ONN-Based Cascaded Framework

  • Sidra Gul,
  • Muhammad Salman Khan,
  • Md Sakib Abrar Hossain,
  • Muhammad E. H. Chowdhury and
  • Md. Shaheenur Islam Sumon

8 December 2024

Background/Objectives: Accurate liver and tumor detection and segmentation are crucial in diagnosis of early-stage liver malignancies. As opposed to manual interpretation, which is a difficult and time-consuming process, accurate tumor detection usin...

  • Article
  • Open Access
1,929 Views
9 Pages

Assessing Patient Health Dynamics by Comparative CT Analysis: An Automatic Approach to Organ and Body Feature Evaluation

  • Dominik Müller,
  • Jakob Christoph Voran,
  • Mário Macedo,
  • Dennis Hartmann,
  • Charlotte Lind,
  • Derk Frank,
  • Björn Schreiweis,
  • Frank Kramer and
  • Hannes Ulrich

8 December 2024

Background/Objectives: The integration of machine learning into the domain of radiomics has revolutionized the approach to personalized medicine, particularly in oncology. Our research presents RadTA (RADiomics Trend Analysis), a novel framework deve...

  • Article
  • Open Access
5 Citations
3,058 Views
39 Pages

Applying Neural Networks to Analyse Inflammatory, Sociodemographic, and Psychological Factors in Non-Melanoma Skin Cancer and Colon Cancer: A Statistical and Artificial Intelligence Approach

  • Răzvan Mercuţ,
  • Marius Eugen Ciurea,
  • Emil Tiberius Traşcă,
  • Mihaela Ionescu,
  • Maria Filoftea Mercuţ,
  • Patricia Mihaela Rădulescu,
  • Cristina Călăraşu,
  • Liliana Streba,
  • Alin Gabriel Ionescu and
  • Dumitru Rădulescu

7 December 2024

Background/Objectives: Chronic inflammation and psychosocial factors significantly influence cancer progression and patient behavior in seeking medical care. Understanding their interplay is essential for enhancing early detection and developing pers...

  • Article
  • Open Access
1,539 Views
11 Pages

Cardiac Magnetic Resonance Imaging with Myocardial Strain Assessment Correlates with Cardiopulmonary Exercise Testing in Patients with Pectus Excavatum

  • André Lollert,
  • Tariq Abu-Tair,
  • Tilman Emrich,
  • Karl-Friedrich Kreitner,
  • Alexander Sterlin,
  • Christoph Kampmann and
  • Gundula Staatz

7 December 2024

Objectives: To evaluate correlations between cardiac magnetic resonance imaging (cMRI) at rest including strain imaging and variables derived from quantitative cardiopulmonary exercise testing using a treadmill in patients with pectus excavatum. Meth...

  • Article
  • Open Access
2,001 Views
11 Pages

Lipoprotein(a) as a Risk Factor for Recurrent Acute Myocardial Infarction and Mortality: Insights from Routine Clinical Practice

  • David Šuran,
  • Vojko Kanič,
  • Peter Kokol,
  • Tadej Završnik,
  • Florjan Verhnjak,
  • Bojan Žlahtič,
  • Andreja Sinkovič and
  • Franjo Husam Naji

7 December 2024

Background: Lipoprotein(a) [Lp(a)] is a well-established risk factor for incident atherosclerotic cardiovascular (CV) disease. However, evidence regarding its association with recurrent events is limited. To address this gap, we conducted a retrospec...

  • Article
  • Open Access
3 Citations
3,009 Views
15 Pages

6 December 2024

Background/Objectives: The purpose of this study was to measure the bone thickness and angulation of the maxillary and mandibular anterior teeth on the buccal and palatal/lingual sides and also to analyze the sagittal root position (SRP) in the alveo...

  • Article
  • Open Access
1,691 Views
10 Pages

The Condition of the Masseter Muscles After Orthodontic Treatment with Fixed Appliances

  • Sebastian Szajkowski,
  • Jarosław Pasek and
  • Grzegorz Cieślar

6 December 2024

Background: One of the methods used in malocclusion treatment is the use of fixed appliances. Research conducted so far has revealed that changes in bite force occurring over the course of orthodontic treatment are directly related to the functional...

  • Article
  • Open Access
21 Citations
4,410 Views
16 Pages

From Binary to Multi-Class Classification: A Two-Step Hybrid CNN-ViT Model for Chest Disease Classification Based on X-Ray Images

  • Yousra Hadhoud,
  • Tahar Mekhaznia,
  • Akram Bennour,
  • Mohamed Amroune,
  • Neesrin Ali Kurdi,
  • Abdulaziz Hadi Aborujilah and
  • Mohammed Al-Sarem

6 December 2024

Background/Objectives: Chest disease identification for Tuberculosis and Pneumonia diseases presents diagnostic challenges due to overlapping radiographic features and the limited availability of expert radiologists, especially in developing countrie...

  • Article
  • Open Access
5 Citations
1,535 Views
11 Pages

The Evaluation of Radiolabeled Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Initial Staging in Intermediate-Risk Prostate Cancer Patients: A Retrospective Multicenter Analysis

  • Laura Evangelista,
  • Priscilla Guglielmo,
  • Giulia Giacoppo,
  • Lucia Setti,
  • Demetrio Aricò,
  • Lorenzo Muraglia,
  • Katia Marzo,
  • Nicolò Buffi,
  • Vittorio Fasulo and
  • Giovanni Lughezzani
  • + 5 authors

6 December 2024

Objectives. The aim of the present study was to assess the performance of radiolabeled-PSMA PET/CT in a cohort of intermediate-risk prostate cancer (PCa) patients for initial staging. Methods. This is a retrospective, multicenter analysis of patients...

  • Article
  • Open Access
3 Citations
1,574 Views
12 Pages

Late Enhancement Computed Tomography for Left Atrial Fibrosis Imaging: A Pilot “Proof-of-Concept” Study

  • Pietro G. Lacaita,
  • Christoph Beyer,
  • Fabian Plank,
  • Markus Stühlinger and
  • Gudrun M. Feuchtner

6 December 2024

Background/Objective: Left atrial (LA) fibrosis imaging improves the guidance of LA catheter ablation. Cardiac computed tomography (CT) may be a reasonable alternative to CMR. The aim was to evaluate late enhancement (LE) fibrosis mapping by CT, and...

  • Review
  • Open Access
1 Citations
1,954 Views
14 Pages

Daily Measurements from Cardiac Implantable Electronic Devices to Assess Health Status

  • Eva Roseboom,
  • Fenna Daniëls,
  • Michiel Rienstra and
  • Alexander H. Maass

6 December 2024

Cardiac implantable electronic devices (CIEDs) such as pacemakers and implantable cardioverter-defibrillators (ICDs) are increasingly used in the aging population. Modern CIEDs perform daily measurements, mainly aimed at discovering early signs of ba...

  • Article
  • Open Access
2 Citations
1,455 Views
14 Pages

6 December 2024

Background: Major diagnostic and therapeutic changes led to the implementation of the ‘lung cancer diagnosis in small biopsies and cytology specimens’ concept in the WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart in 2...

  • Article
  • Open Access
1 Citations
2,190 Views
11 Pages

Diabetic Mastopathy: A Monocentric Study to Explore This Uncommon Breast Disease

  • Luciano Mariano,
  • Luca Nicosia,
  • Sofia Scolari,
  • Sara Pasi,
  • Sofia Netti,
  • Giovanni Mazzarol,
  • Antuono Latronico and
  • Enrico Cassano

6 December 2024

Background: Diabetic Mastopathy (DMP) is an uncommon benign fibro-inflammatory condition that occurs in women with long-standing diabetes mellitus (DM), particularly type 1. It often mimics breast cancer (BC) in clinical and imaging presentations, le...

  • Article
  • Open Access
1 Citations
1,409 Views
13 Pages

6 December 2024

Objective: This retrospective cohort study assessed dementia risk in epilepsy patients associated with the compliance to epileptic treatment visits. Methods: We used Taiwanese insurance claims data to establish an epilepsy cohort (N = 39,216) diagnos...

  • Article
  • Open Access
2 Citations
3,875 Views
13 Pages

6 December 2024

Background/Objectives: To assess the incidence of and risk factors for black triangles between the central incisors after orthodontic treatment; Methods: Ninety-seven post-treatment patients (29 men and 68 women; mean age, 22.7 years) were retrospect...

  • Article
  • Open Access
2 Citations
2,361 Views
10 Pages

Serum Tau Species in Progressive Supranuclear Palsy: A Pilot Study

  • Costanza Maria Cristiani,
  • Luana Scaramuzzino,
  • Elvira Immacolata Parrotta,
  • Giovanni Cuda,
  • Aldo Quattrone and
  • Andrea Quattrone

5 December 2024

Background/Objectives: Progressive Supranuclear Palsy (PSP) is a tauopathy showing a marked symptoms overlap with Parkinson’s Disease (PD). PSP pathology suggests that tau protein might represent a valuable biomarker to distinguish between the...

  • Article
  • Open Access
2,680 Views
10 Pages

The Clinical Utility of Assessing Orthostatic Intolerance in Adolescents with Sport-Related Concussion, a Retrospective Study

  • Mohammad N. Haider,
  • Jule Deren,
  • Karim Khaled,
  • Cathlyn Corrado,
  • Haley M. Chizuk,
  • Jeffrey C. Miecznikowski and
  • John J. Leddy

5 December 2024

Background/Objective: Assessing Orthostatic Intolerance (OI, symptoms upon standing from supine) is recommended in athletes with sport-related concussions (SRCs), as this is caused by impairments in the cardiovascular autonomic nervous system (cANS)....

  • Review
  • Open Access
2 Citations
3,521 Views
15 Pages

The Association Between Antipsychotics and Bone Fragility: An Updated Comprehensive Review

  • Michele Mercurio,
  • Giovanna Spina,
  • Olimpio Galasso,
  • Giorgio Gasparini,
  • Cristina Segura-Garcia,
  • Pasquale De Fazio and
  • Renato de Filippis

5 December 2024

Background: Antipsychotic drugs appear to be related to reduced bone mineral density (BMD). We conducted a narrative review to collect the available literature investigating the relationship between antipsychotic use and bone fragility. Methods: A re...

  • Article
  • Open Access
3 Citations
1,899 Views
17 Pages

Instrument-Free Point-of-Care Diagnostic for Leishmania Parasites

  • Taralyn J. Wiggins,
  • Ruonan Peng,
  • Ruth V. Bushnell,
  • John K. Tobin,
  • David A. MacLeod,
  • Ke Du,
  • Gregory J. Tobin and
  • Stephen J. Dollery

5 December 2024

Background/Objective: Leishmaniasis is the second deadliest parasitic disease in the world, after malaria, with an estimated 1.6 million new cases each year. While cutaneous leishmaniasis can result in permanent scars from lesions after treatment, th...

  • Article
  • Open Access
4 Citations
1,625 Views
15 Pages

5 December 2024

Background: For a single exposure in radiography, a dual-layer flat-panel detector (DFD) can provide spectral images and efficiently utilize the transmitted X-ray photons to improve the detective quantum efficiency (DQE) performance. In this paper, t...

  • Systematic Review
  • Open Access
11 Citations
2,687 Views
11 Pages

Quality Assessment of MRI-Radiomics-Based Machine Learning Methods in Classification of Brain Tumors: Systematic Review

  • Shailesh S. Nayak,
  • Saikiran Pendem,
  • Girish R. Menon,
  • Niranjana Sampathila and
  • Prakashini Koteshwar

5 December 2024

Background: Brain tumors present a complex challenge in clinical oncology, where precise diagnosis and classification are pivotal for effective treatment planning. Radiomics, a burgeoning field in neuro-oncology, involves extracting and analyzing num...

  • Article
  • Open Access
1,676 Views
19 Pages

5 December 2024

Background: Tibiofibula fractures occur across all age groups, and postoperative complications are frequent. An accurate and rapid classification methodology for these fractures could significantly assist physicians. Clinically, tibiofibula fractures...

  • Article
  • Open Access
1,988 Views
11 Pages

Comparison of Modified Labor Induction Strategies for Pregnant Women at a Single Tertiary Center Before and During the COVID-19 Pandemic

  • Yi-Sin Tan,
  • Ching-Chang Tsai,
  • Hsin-Hsin Cheng,
  • Yun-Ju Lai,
  • Pei-Fang Lee,
  • Te-Yao Hsu and
  • Kun-Long Huang

5 December 2024

Background: The COVID-19 pandemic has substantially impacted healthcare systems and obstetric practices worldwide. Labor induction is a common procedure for preventing obstetric complications in high-risk populations. This study evaluated perinatal o...

  • Article
  • Open Access
4 Citations
4,187 Views
10 Pages

Fournier’s Gangrene Mortality Index (FGMI): A New Scoring System for Predicting Fournier’s Gangrene Mortality

  • Hüseyin Yönder,
  • Mehmet Çelik,
  • Mehmet Sait Berhuni,
  • Ahmed Cihad Genç,
  • Hasan Elkan,
  • Faik Tatlı,
  • Abdullah Özgönül,
  • Felat Çiftçi,
  • Fırat Erkmen and
  • Ali Uzunköy
  • + 1 author

5 December 2024

Objectives: Fournier’s gangrene is an aggressive, rapidly progressing, and life-threatening necrotizing fasciitis of the perineal and genital regions. Various scoring systems have been developed for predicting survival and prognosis in Fournier...

  • Article
  • Open Access
12 Citations
4,027 Views
18 Pages

5 December 2024

Background: Malaria is a life-threatening disease spread by infected mosquitoes, affecting both humans and animals. Its symptoms range from mild to severe, including fever, muscle discomfort, coma, and kidney failure. Accurate diagnosis is crucial bu...

  • Article
  • Open Access
1,466 Views
12 Pages

Nosocomial Bacterial Bronchopneumonia and SARS-CoV-2 Pneumonia in Patients with Traumatic Injuries: Imaging Aspects and Macroscopic and Microscopic Findings of Lung Tissue

  • Georgiana-Denisa Gavriliţă,
  • Ştefania Ungureanu,
  • Ecaterina Dăescu,
  • Mircea-Nicu Gavriliță,
  • Cristian-Cosmin Ţîncu and
  • Alexandra Enache

5 December 2024

Background: Patients with traumatic injuries often represent the best hosts for healthcare-associated infections, especially pneumonia or bronchopneumonia. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic raised serious probl...

  • Article
  • Open Access
4 Citations
1,562 Views
12 Pages

Efficacy of the Geriatric Trauma Outcome Score (GTOS) in Predicting Mortality in Trauma Patients: A Retrospective Cross-Sectional Study

  • Ching-Ya Huang,
  • Shao-Chun Wu,
  • Tsan-Shiun Lin,
  • Pao-Jen Kuo,
  • Johnson Chia-Shen Yang,
  • Shiun-Yuan Hsu and
  • Ching-Hua Hsieh

5 December 2024

Background: Trauma has a profound impact on mortality as well as short- and long-term health outcomes. For trauma patients to receive medical care in a timely manner, early identification and risk assessment are essential. The Geriatric Trauma Outcom...

  • Article
  • Open Access
9 Citations
7,393 Views
36 Pages

5 December 2024

Background: Tuberculosis (TB) is a bacterial disease that mainly affects the lungs, but it can also impact other parts of the body, such as the brain, bones, and kidneys. The disease is caused by a bacterium called Mycobacterium tuberculosis and spre...

  • Article
  • Open Access
7 Citations
1,930 Views
13 Pages

Advancing Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Diagnosis: A Comparative Analysis of Machine Learning Methodologies

  • Joseph J. Janicki,
  • Bernadette M. M. Zwaans,
  • Sarah N. Bartolone,
  • Elijah P. Ward and
  • Michael B. Chancellor

5 December 2024

Background/Objectives. This study aimed to improve machine learning models for diagnosing interstitial cystitis/bladder pain syndrome (IC/BPS) by comparing classical machine learning methods with newer AutoML approaches, utilizing biomarker data and...

  • Article
  • Open Access
3 Citations
1,709 Views
15 Pages

Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department

  • Nadya Kagansky,
  • David Mazor,
  • Ayashi Wajdi,
  • Yulia Maler Yaron,
  • Miya Sharfman,
  • Tomer Ziv Baran,
  • Dana Kagansky,
  • Gal Pachys,
  • Yochai Levy and
  • Daniel Trotzky

5 December 2024

Background: Chest pain is one of the most common reasons for emergency department (ED) visits. Patients presenting with inconclusive symptoms complicate the diagnostic process and add to the burden upon the ED. This study aimed to determine factors p...

  • Article
  • Open Access
1 Citations
1,607 Views
12 Pages

4 December 2024

Background: Artificial intelligence (AI) tools, like ChatGPT, are gaining attention for their potential in supporting clinical decisions. This study evaluates the performance of ChatGPT-4o in acute cardiological cases compared to cardiologists and em...

  • Review
  • Open Access
6 Citations
7,728 Views
22 Pages

Echocardiography in the Assessment of Heart Failure Patients

  • Frank L. Dini,
  • Matteo Cameli,
  • Andrea Stefanini,
  • Hatem Soliman Aboumarie,
  • Matteo Lisi,
  • Per Lindqvist and
  • Michael Y. Henein

4 December 2024

Doppler echocardiography is the corner-stone of non-invasive investigation of patients with a clinical diagnosis of heart failure. It provides an accurate and quantitative assessment of cardiac structure and function. Furthermore, spectral Doppler me...

  • Article
  • Open Access
5 Citations
4,135 Views
12 Pages

Mobile App Intervention Increases Adherence to Home Exercise Program After Whiplash Injury—A Randomized Controlled Trial (RCT)

  • Blaž Barun,
  • Zdravko Divić,
  • Dušanka Martinović Kaliterna,
  • Ana Poljičanin,
  • Benjamin Benzon and
  • Jure Aljinović

4 December 2024

Objective: Can mobile app intervention via push notifications increase adherence to exercise and reduce disability and pain after a whiplash injury? Methods: A randomized controlled trial was conducted with concealed allocation, blinding of some asse...

  • Article
  • Open Access
2 Citations
2,479 Views
38 Pages

4 December 2024

Objectives: This study investigates disruptions in functional brain networks in Parkinson’s Disease (PD), using advanced modeling and machine learning. Functional networks were constructed using the Nonlinear Autoregressive Distributed Lag (NAR...

  • Interesting Images
  • Open Access
1,054 Views
6 Pages

4 December 2024

Gastric duplication cysts (GDCs) are rare congenital anomalies, often identified during infancy or childhood. Although typically benign, there have been sporadic reports of malignant transformations, including adenocarcinoma and rare mixed tumors. He...

  • Article
  • Open Access
2 Citations
2,078 Views
9 Pages

The Role of Prenatal Ultrasound Examination in Predicting the Outcomes of Ovarian Fetal Cysts: A Pictorial Essay

  • Elisa Montaguti,
  • Benedetta Petrachi,
  • Marta Fiorentini,
  • Viola Arosio,
  • Sara Doroldi,
  • Camilla Dionisi,
  • Vito Bernardi and
  • Gianluigi Pilu

4 December 2024

Objectives: The aim of this study was to evaluate prenatal ultrasound features, fetal postnatal outcomes, and the need for postnatal surgery in the suspicion of ovarian torsion. Methods: We included patients with a singleton pregnancy with a suspicio...

  • Article
  • Open Access
3 Citations
1,764 Views
11 Pages

Obesity: Friend or Foe in Sjögren’s Syndrome Patients?

  • Kincső Mezei,
  • Laura Nagy,
  • Viktória Orosz,
  • Zsófia Aradi,
  • Bernadett Bói and
  • Antónia Szántó

3 December 2024

Background/Objectives: In Sjögren’s syndrome, exocrine glands are destructed in an autoimmune-mediated process. Obesity is known to influence a wide range of diseases. This study aimed to examine whether obesity has an impact on the diseas...

  • Article
  • Open Access
2 Citations
3,459 Views
12 Pages

Smartphone-Based Pupillometry Using Machine Learning for the Diagnosis of Sports-Related Concussion

  • Anthony J. Maxin,
  • Bridget M. Whelan,
  • Michael R. Levitt,
  • Lynn B. McGrath and
  • Kimberly G. Harmon

3 December 2024

Background: Quantitative pupillometry has been proposed as an objective means to diagnose acute sports-related concussion (SRC). Objective: To assess the diagnostic accuracy of a smartphone-based quantitative pupillometer in the acute diagnosis of SR...

  • Review
  • Open Access
5 Citations
2,022 Views
18 Pages

Molecular Biomarkers in Cutaneous Photodynamic Therapy: A Comprehensive Review

  • Jorge Naharro-Rodriguez,
  • Stefano Bacci and
  • Montserrat Fernandez-Guarino

3 December 2024

Background/Objectives: Photodynamic therapy (PDT) is widely utilized in dermatology for the treatment of various skin conditions. Despite its effectiveness, the exact biomolecular changes underlying therapeutic outcomes remain only partially understo...

  • Article
  • Open Access
1 Citations
1,485 Views
13 Pages

Near-Wall Slow Flow Contributes to Wall Enhancement of Middle Cerebral Artery Bifurcation Aneurysms on Vessel Wall MRI

  • Linfeng Liu,
  • Zhuhao Li,
  • Weiping Xiao,
  • Yibing Yang,
  • Yan Yan,
  • Lu Bai,
  • Lingzhi Quan,
  • Tiewei Qi and
  • Feng Liang

3 December 2024

Background: The mechanism of aneurysm wall enhancement (AWE) in middle cerebral artery (MCA) bifurcation aneurysms on vessel wall magnetic resonance imaging (VW-MRI) remains unclear. We aimed to explore the morphologically related hemodynamic mechani...

  • Article
  • Open Access
1 Citations
1,309 Views
11 Pages

The Applicability and Limitations of the Spectrofluorometric Method for Determination of ALDH1 Activity in Serum and Plasma

  • Sylwia Michorowska,
  • Agnieszka Wiśniewska,
  • Renata Wolinowska,
  • Piotr Wroczyński and
  • Joanna Giebułtowicz

3 December 2024

Background: Aldehyde dehydrogenase class 1 (ALDH1) is an enzyme that is ubiquitously distributed in adult tissues and may serve as a prognostic marker in various cancer types. In blood, 99% of ALDH1 is found in erythrocytes; although, it was also dem...

  • Article
  • Open Access
1 Citations
1,425 Views
12 Pages

The Impact of Microenvironment and Dysplasia Types on the Prognosis of Myelodysplastic Syndrome

  • Irem Guvendir Bakkaloglu,
  • Itir Ebru Zemheri,
  • Ali Hakan Kaya and
  • Emrah Kilicaslan

3 December 2024

Background: A detailed examination of bone marrow (BM) aspiration and biopsy can provide clues regarding the course of the disease as well as the diagnostic features of myelodysplastic syndrome (MDS). Methods: Our aim is to reveal the histomorphologi...

  • Article
  • Open Access
5 Citations
3,339 Views
22 Pages

Enhanced Panoramic Radiograph-Based Tooth Segmentation and Identification Using an Attention Gate-Based Encoder–Decoder Network

  • Salih Taha Alperen Özçelik,
  • Hüseyin Üzen,
  • Abdulkadir Şengür,
  • Hüseyin Fırat,
  • Muammer Türkoğlu,
  • Adalet Çelebi,
  • Sema Gül and
  • Nebras M. Sobahi

3 December 2024

Background: Dental disorders are one of the most important health problems, affecting billions of people all over the world. Early diagnosis is important for effective treatment planning. Precise dental disease segmentation requires reliable tooth nu...

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Diagnostics - ISSN 2075-4418