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Life, Volume 15, Issue 1

January 2025 - 133 articles

Cover Story: This study investigates thermal shrinkage, a technique widely applied in reconstructive surgery, focusing on its impact on wound size, tissue temperature, and oxygenation. Using modern imaging tools and histological analysis, the authors examined the effects of shrinkage on human skin in vitro and in clinical settings. Results showed a significant average reduction in wound area (47%) and structural reorganization of collagen fibers, accompanied by a moderate temperature increase to 65°C. Oxygen saturation exhibited minor declines without adversely affecting healing outcomes. These findings emphasize shrinkage's utility in enhancing surgical precision and suggest its potential for broader applications in wound management and graft optimization. View this paper
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Articles (133)

  • Review
  • Open Access
1 Citations
4,345 Views
23 Pages

Redefining the Tea Green Leafhopper: Empoasca onukii Matsuda (Hemiptera: Cicadellidae) as a Vital Asset in Premium Tea Production

  • Unisa Conteh Kanu,
  • Zhaohong Wang,
  • Chenshi Qiu,
  • Qiaojun Wen,
  • Xueyan Li,
  • Dongliang Qiu,
  • Yinwei Gan and
  • Runqian Mao

20 January 2025

This review explores the evolving role of the tea green leafhopper, Empoasca onukii, in the tea industry, transitioning from a recognized pest to a significant enhancer of tea quality. Recent research highlights how its feeding behavior stimulates th...

  • Article
  • Open Access
2 Citations
2,540 Views
14 Pages

Limitations of the Boston Carpal Tunnel Questionnaire in Assessing Severity in a Homogeneous Occupational Cohort

  • Venera Cristina Dinescu,
  • Marius Bica,
  • Ramona Constantina Vasile,
  • Andrei Gresita,
  • Bogdan Catalin,
  • Alexandra Daniela Rotaru-Zavaleanu,
  • Florentin Ananu Vreju,
  • Lorena Sas and
  • Marius Bunescu

20 January 2025

Background: Carpal tunnel syndrome (CTS) is a common peripheral neuropathy, often assessed using the Boston Carpal Tunnel Questionnaire (BCTQ). The BCTQ evaluates symptom severity (SSS) and functional status (FSS) but has limitations in stratifying C...

  • Study Protocol
  • Open Access
2 Citations
3,025 Views
13 Pages

Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction—A Study Protocol

  • Hanna Maria Dragoș,
  • Adina Stan,
  • Livia Livinț Popa,
  • Roxana Pintican,
  • Diana Feier,
  • Nicu Cătălin Drăghici,
  • Dragoș-Cătălin Jianu,
  • Diana Chira,
  • Ștefan Strilciuc and
  • Dafin F. Mureșanu

20 January 2025

Acute ischemic stroke (AIS) is frequently associated with long-term post-stroke cognitive impairment (PSCI) and dementia. While the mechanisms behind PSCI are not fully understood, the brain and cognitive reserve concepts are topics of ongoing resear...

  • Systematic Review
  • Open Access
2 Citations
8,802 Views
27 Pages

Metformin for Treating Gestational Diabetes: What Have We Learned During the Last Two Decades? A Systematic Review

  • Angeliki Gerede,
  • Ekaterini Domali,
  • Christos Chatzakis,
  • Chrysoula Margioula-Siarkou,
  • Stamatios Petousis,
  • Sofoklis Stavros,
  • Konstantinos Nikolettos,
  • Evanthia Gouveri,
  • Sotirios Sotiriou and
  • Panagiotis Tsikouras
  • + 5 authors

20 January 2025

There has been accumulating evidence over the past two decades that metformin can be an effective treatment for gestational diabetes mellitus (GDM) in women whose diet and exercise fail to attain optimal glycemic control. The objective of this review...

  • Article
  • Open Access
1 Citations
1,640 Views
11 Pages

Spleno-Mesenteric Venous Blood Flow Dynamics in Adult Patients with Chronic Portal Vein Thrombosis Analyzed by Sequential CT-Spleno- and Mesenterico-Portography

  • Alexandra Schlitt,
  • Andrea Goetz,
  • Christian Stroszczynski,
  • Florian Zeman,
  • Christina Hackl,
  • Hans J. Schlitt,
  • Ernst-Michael Jung,
  • Wibke Uller and
  • Simone Hammer

20 January 2025

Background: Portal vein thrombosis (PVT) leads to portal hypertension (PH) with its sequelae. Computed tomography spleno-mesenterico-portography (CT-SMPG) combines sequential CT spleno-portography and CT mesenterico-portography. CT-SMPG comprehensive...

  • Article
  • Open Access
4,790 Views
16 Pages

20 January 2025

The aim of this study was to investigate the effects and potential mechanisms of 8-week transcranial direct-current stimulation (tDCS) combined with resistance training (RT) on pull-up performance in male college students. Twenty-five male college st...

  • Article
  • Open Access
2,112 Views
18 Pages

Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration

  • Anastasia Alexandrova,
  • Elizaveta Kontareva,
  • Margarita Pustovalova,
  • Sergey Leonov and
  • Yulia Merkher

19 January 2025

Cancer-related deaths primarily occur due to metastasis, a process involving the migration and invasion of cancer cells. In most solid tumors, metastasis occurs through collective cell migration (CCM), guided by “cellular leaders”. These...

  • Article
  • Open Access
1 Citations
2,028 Views
27 Pages

Detection of Insulin in Insulin-Deficient Islets of Patients with Type 1 Diabetes

  • Yuliya Krivova,
  • Alexandra Proshchina,
  • Dmitry Otlyga,
  • Anastasia Kharlamova and
  • Sergey Saveliev

19 January 2025

Type 1 diabetes (T1D) is related to the autoimmune destruction of β-cells, leading to their almost complete absence in patients with longstanding T1D. However, endogenous insulin secretion persists in such patients as evidenced by the measuremen...

  • Review
  • Open Access
8 Citations
5,264 Views
34 Pages

Post-Translational Modifications of Proteins Orchestrate All Hallmarks of Cancer

  • Pathea Shawnae Bruno,
  • Aneeta Arshad,
  • Maria-Raluca Gogu,
  • Natalie Waterman,
  • Rylie Flack,
  • Kimberly Dunn,
  • Costel C. Darie and
  • Anca-Narcisa Neagu

18 January 2025

Post-translational modifications (PTMs) of proteins dynamically build the buffering and adapting interface between oncogenic mutations and environmental stressors, on the one hand, and cancer cell structure, functioning, and behavior. Aberrant PTMs c...

  • Article
  • Open Access
2,316 Views
13 Pages

Fluid Resuscitation and Initial Management in Patients Presenting with Sepsis in the General Ward

  • Sung Won Chang,
  • Juwhan Choi,
  • Jee Youn Oh,
  • Young Seok Lee,
  • Kyung Hoon Min,
  • Gyu Young Hur,
  • Sung Yong Lee,
  • Jae Jeong Shim and
  • Jae Kyeom Sim

18 January 2025

The optimal management of hospital-presenting sepsis remains poorly understood. We investigated the initial management in patients presenting with sepsis in the general ward, the association between fluid resuscitation and clinical outcomes, and the...

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Life - ISSN 2075-1729