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Life, Volume 10, Issue 4

April 2020 - 20 articles

Cover Story: Moons in the outer solar system appear to have liquid water beneath an ice crust and conditions that may support life. Plumes of water have been observed to erupt from Europa and Enceladus, the moons of Jupiter and Saturn, and these are targets in the search for life beyond Earth. One criterion for convincing life-detection measurement is that the environment that the sample encounters does not destroy the targeted signs of life. Knowledge of the type and expected quantity of biomarkers in icy world plumes will enable detection and sensitivity limits to be set for proposed life detection instrumentation. Our work focuses on understanding the physical response of aqueous microorganisms to the highly desiccating and freezing conditions encountered if they are ejected into vacuum. View this paper
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Articles (20)

  • Communication
  • Open Access
3 Citations
3,535 Views
10 Pages

Maternal Obesity Modulates Expression of Satb2 in Hypothalamic VMN of Female Offspring

  • Kelly A. Glendining,
  • Lorryn C. Fisher and
  • Christine L. Jasoni

24 April 2020

Maternal obesity during pregnancy is associated with a greater risk of poor health outcomes in offspring, including obesity, metabolic disorders, and anxiety, however the incidence of these diseases differs for males and females. Similarly, animal mo...

  • Review
  • Open Access
32 Citations
14,935 Views
17 Pages

Enigmatic Histamine Receptor H4 for Potential Treatment of Multiple Inflammatory, Autoimmune, and Related Diseases

  • Pakhuri Mehta,
  • Przemysław Miszta,
  • Przemysław Rzodkiewicz,
  • Olga Michalak,
  • Piotr Krzeczyński and
  • Sławomir Filipek

24 April 2020

The histamine H4 receptor, belonging to the family of G-protein coupled receptors, is an increasingly attractive drug target. It plays an indispensable role in many cellular pathways, and numerous H4R ligands are being studied for the treatment of se...

  • Article
  • Open Access
28 Citations
10,381 Views
25 Pages

Rocket Science: The Effect of Spaceflight on Germination Physiology, Ageing, and Transcriptome of Eruca sativa Seeds

  • Jake O. Chandler,
  • Fabian B. Haas,
  • Safina Khan,
  • Laura Bowden,
  • Michael Ignatz,
  • Eugenia M. A. Enfissi,
  • Frances Gawthrop,
  • Alistair Griffiths,
  • Paul D. Fraser and
  • Stefan A. Rensing
  • + 1 author

24 April 2020

In the ‘Rocket Science’ project, storage of Eruca sativa (salad rocket) seeds for six months on board the International Space Station resulted in delayed seedling establishment. Here we investigated the physiological and molecular mechani...

  • Article
  • Open Access
22 Citations
4,647 Views
15 Pages

Association between Occupational Noise and Vibration Exposure and Insomnia among Workers in Korea

  • Fatima Nari,
  • Yun Kyung Kim,
  • Soo Hyun Kang,
  • Eun-Cheol Park and
  • Sung-In Jang

22 April 2020

Background: The effect of noise and vibration exposure on disturbed sleep has been investigated in the past. However, this study was carried out to investigate the relationship between workplace noise and vibration exposure with insomnia amongst repr...

  • Article
  • Open Access
57 Citations
7,500 Views
15 Pages

22 April 2020

The cyanobacterium Synechocystis sp. PCC 6803 is known for producing polyhydroxybutyrate (PHB) under unbalanced nutrient conditions. Although many cyanobacteria produce PHB, its physiological relevance remains unknown, since previous studies conclude...

  • Article
  • Open Access
9 Citations
3,979 Views
13 Pages

pH-Dependent Adsorption of Peptides on Montmorillonite for Resisting UV Irradiation

  • Rongcan Lin,
  • Yueqiao Wang,
  • Xin Li,
  • Yan Liu and
  • Yufen Zhao

20 April 2020

Ultraviolet (UV) irradiation is considered an energy source for the prebiotic chemical synthesis of life’s building blocks. However, it also results in photodegradation of biology-related organic compounds on early Earth. Thus, it is important...

  • Article
  • Open Access
4 Citations
4,346 Views
6 Pages

17 April 2020

Recently, a 30-cm object was discovered to graze the Earth’s atmosphere and shift into a Jupiter-crossing orbit. We use the related survey parameters to calibrate the total number of such objects. The number of objects that could have exported...

  • Communication
  • Open Access
9 Citations
3,951 Views
12 Pages

Towards Determining Biosignature Retention in Icy World Plumes

  • Kathryn Bywaters,
  • Carol R. Stoker,
  • Nelio Batista Do Nascimento and
  • Lawrence Lemke

16 April 2020

With the discovery of the persistent jets of water being ejected to space from Enceladus, an understanding of the effect of the space environment on potential organisms and biosignatures in them is necessary for planning life detection missions. We e...

  • Review
  • Open Access
25 Citations
6,318 Views
17 Pages

Radiation-Induced Cerebro-Ophthalmic Effects in Humans

  • Konstantin N. Loganovsky,
  • Donatella Marazziti,
  • Pavlo A. Fedirko,
  • Kostiantyn V. Kuts,
  • Katerina Y. Antypchuk,
  • Iryna V. Perchuk,
  • Tetyana F. Babenko,
  • Tetyana K. Loganovska,
  • Olena O. Kolosynska and
  • George Y. Kreinis
  • + 11 authors

16 April 2020

Exposure to ionizing radiation (IR) could affect the human brain and eyes leading to both cognitive and visual impairments. The aim of this paper was to review and analyze the current literature, and to comment on the ensuing findings in the light of...

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Life - ISSN 2075-1729Creative Common CC BY license