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Article

A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism

1
Lehrstuhl für Biochemie, Department Chemie, Technische Universität München, Lichtenbergstraße 4, 85748 Garching, Germany
2
209 Mill Race Drive, Chapel Hill, NC 27514, USA
*
Author to whom correspondence should be addressed.
These authors contributed equally.
Life 2020, 10(4), 35; https://doi.org/10.3390/life10040035
Received: 9 March 2020 / Revised: 3 April 2020 / Accepted: 4 April 2020 / Published: 7 April 2020
(This article belongs to the Special Issue Frontiers of Astrobiology)
Carbon fixation, in addition to the evolution of metabolism, is a main requirement for the evolution of life. Here, we report a one-pot carbon fixation of acetylene (C2H2) and carbon monoxide (CO) by aqueous nickel sulfide (NiS) under hydrothermal (>100 °C) conditions. A slurry of precipitated NiS converts acetylene and carbon monoxide into a set of C2–4-products that are surprisingly representative for C2–4-segments of all four central CO2-fixation cycles of the domains Bacteria and Archaea, whereby some of the products engage in the same interconversions, as seen in the central CO2-fixation cycles. The results suggest a primordial, chemically predetermined, non-cyclic acetyleno/carboxydotrophic core metabolism. This metabolism is based on aqueous organo–metal chemistry, from which the extant central CO2-fixation cycles based on thioester chemistry would have evolved by piecemeal modifications. View Full-Text
Keywords: origin of life; chemical evolution; early metabolism; transition metal catalysis; carbon fixation; nickel sulfide; acetylene; carbon monoxide origin of life; chemical evolution; early metabolism; transition metal catalysis; carbon fixation; nickel sulfide; acetylene; carbon monoxide
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MDPI and ACS Style

Sobotta, J.; Geisberger, T.; Moosmann, C.; Scheidler, C.M.; Eisenreich, W.; Wächtershäuser, G.; Huber, C. A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism. Life 2020, 10, 35. https://doi.org/10.3390/life10040035

AMA Style

Sobotta J, Geisberger T, Moosmann C, Scheidler CM, Eisenreich W, Wächtershäuser G, Huber C. A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism. Life. 2020; 10(4):35. https://doi.org/10.3390/life10040035

Chicago/Turabian Style

Sobotta, Jessica, Thomas Geisberger, Carolin Moosmann, Christopher M. Scheidler, Wolfgang Eisenreich, Günter Wächtershäuser, and Claudia Huber. 2020. "A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism" Life 10, no. 4: 35. https://doi.org/10.3390/life10040035

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