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Nutrients, Volume 17, Issue 12

June-2 2025 - 107 articles

Cover Story: Vitamin B3 is a water-soluble vitamin found in various food groups. It is often referred to as niacin, nicotinamide, or nicotinamide riboside (NR). Vitamin B3 is a critical component of the oxidized state of nicotinamide adenine dinucleotide (NAD+), which serves as a redox cofactor in various metabolic reactions and exhibits neuroprotective properties by mitigating oxidative stress. NAD+ levels sharply decline with age, contributing to aging-related diseases. Limited NAD+ bioavailability negatively affects sleep, cognitive function, mitochondrial function, and insulin sensitivity. However, supplementation with vitamin B3 (as NR, nicotinamide mononucleotide, or nicotinamide dinucleotide) may increase NAD+ levels. In this review, we examine the current state of scientific knowledge on the effects of vitamin B3 supplementation on sleep. View this paper
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Articles (107)

  • Review
  • Open Access
2 Citations
3,919 Views
14 Pages

Beyond Folate: The Emerging Role of Maternal Vitamin B12 in Neural Tube Development

  • Lirong Nie,
  • Xinru Liu,
  • Xiaoxue Li,
  • Ziyang Ren,
  • Xiao Cheng,
  • Yuwei Wu,
  • Zhiwen Li and
  • Jufen Liu

19 June 2025

Background/Objectives: Folic acid (FA) supplementation can effectively reduce the occurrence of neural tube defects (NTDs). Vitamin B12 is involved in folate metabolism; however, studies have not reached a definitive conclusion on the association bet...

  • Article
  • Open Access
1,166 Views
19 Pages

Targeting Metabolic Syndrome with a Pre-Conception True-Couples-Based Lifestyle Intervention: A Pre-Post Mixed-Methods Evaluation

  • Sundus Nizamani,
  • Catherine R. Knight-Agarwal,
  • Li Li,
  • Alexandria N. Mekanna and
  • Rosemary Anne McFarlane

18 June 2025

Background/Objectives: Metabolic syndrome (Mets) risk is influenced by both parents’ preconception lifestyle, yet most interventions target individuals rather than couples. True couples-based interventions that engage both partners equally rema...

  • Article
  • Open Access
1 Citations
808 Views
14 Pages

The Influence of Solar-Simulated UV Radiation on Circulating 25(OH)D3, 24,25(OH)2D3 and Their Ratio in Younger and Older Adults

  • Oktawia P. Borecka,
  • Jonathan C. Y. Tang,
  • William D. Fraser,
  • Lesley E. Rhodes and
  • Ann R. Webb

18 June 2025

Background: In addition to the well-known vitamin D metabolites 25(OH)D and 1,25(OH)2D, the catabolite 24,25(OH)2D may also reflect vitamin D status and influence biological and skeletal processes. However, the effects of UVR-induced synthesis on 24,...

  • Article
  • Open Access
1,225 Views
26 Pages

18 June 2025

Background/Objectives: Fruits and vegetables (F&Vs) are major dietary sources of phytochemicals, crucial for preventing non-communicable diseases. However, barriers such as preparation inconvenience and a short shelf life hinder their consumption...

  • Article
  • Open Access
3,183 Views
21 Pages

Acute Malnutrition in Under-Five Children in KwaZulu-Natal, South Africa: Risk Factors and Implications for Dietary Quality

  • Meshack Mzamani Mathosi,
  • Lindiwe Priscilla Cele,
  • Mmampedi Mathibe and
  • Perpetua Modjadji

18 June 2025

Background/Objectives: Despite ongoing national interventions, pockets of acute malnutrition persist in rural settings of South Africa, contributing to disproportionate rates of child morbidity and mortality. This study aimed to identify risk factors...

  • Article
  • Open Access
2,564 Views
16 Pages

Comparison of Preconception Diet Scores Across Studies: The PrePARED Consortium

  • Lixuan Ji,
  • Janaki Sundaresan,
  • Cailey Cranny,
  • Ke Pan,
  • Danielle Symons Downs,
  • Erica P. Gunderson,
  • Gita Mishra,
  • Abigail Pauley,
  • Kaitlin S. Potts and
  • James M. Shikany
  • + 3 authors

18 June 2025

Background: Preconception diet and nutritional status are important determinants of reproductive and pregnancy health. As a comprehensive evaluation, this paper describes harmonization of diet data across multiple cohorts including over 50,000 partic...

  • Article
  • Open Access
1 Citations
6,096 Views
17 Pages

Beneficial Effect of the Mediterranean Diet on the Reduction of Prediabetes—Results of the Bialystok PLUS Study

  • Magdalena Zalewska,
  • Małgorzata E. Zujko,
  • Jacek Jamiołkowski,
  • Małgorzata Chlabicz,
  • Magda Łapińska and
  • Karol A. Kamiński

18 June 2025

Background: The Mediterranean diet is considered one of the healthiest and safest diets for preventing chronic diseases. The primary objective of this study was to assess the association between adherence to the Mediterranean diet and the occurrence...

  • Article
  • Open Access
3 Citations
10,932 Views
21 Pages

18 June 2025

Introduction: The purpose of this study was to evaluate effects of post-exercise protein supplementation with combined resistance and interval training on total insulin-like growth factor-1 (IGF-1) concentration, strength (3RM), and body composition...

  • Article
  • Open Access
1,494 Views
13 Pages

Laboratory and Clinical Practices in the Study of Coeliac Disease in Children and Adults: Recommendations from a Spanish Multicentre Survey

  • Rocío Aguado,
  • Juan Irure-Ventura,
  • Maria Luisa Vargas,
  • Garbiñe Roy,
  • Yvelise Barrios,
  • Laura Martínez-Martínez,
  • Beatriz Rodríguez,
  • Marco Antonio Montes-Cano,
  • Marcos López-Hoyos and
  • Aurora Jurado

18 June 2025

Background/Objectives: Coeliac disease is an immune-mediated disorder of the gastrointestinal tract that may result in significant nutritional deficiencies. Effective management requires strict, lifelong adherence to a gluten-free diet. Both underdia...

  • Article
  • Open Access
1,505 Views
15 Pages

Food Allergy Prevalence and Characteristics Among Adults in Cyprus: Effects on Health-Related Quality of Life

  • Stella A. Nicolaou,
  • Alisa Thuy Anh Pham,
  • Afroditi Alexandrou,
  • Elena Andreou,
  • Elena C. Papanastasiou and
  • Nicolaos Nicolaou

18 June 2025

Background/Objectives: Food allergy (FA) is an increasing global concern, yet its prevalence, characteristics, and management vary across populations. Country-specific differences have also been observed in the health-related quality of life (HRQL) o...

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Nutrients - ISSN 2072-6643