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Nutrients, Volume 10, Issue 7 (July 2018)
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Cover Story (view full-size image) Protein hydrolysates are recognized as a potent source of bioactive peptides, including many [...] Read more. Protein hydrolysates are recognized as a potent source of bioactive peptides, including many immunomodulatory peptides. Consuming protein hydrolysates has been found to induce a variety of immune effects, both locally in the intestine and mesenteric lymph nodes, as well as systemically. Hydrolysates containing these peptides might therefore be helpful in the management of many immune related western diseases, like inflammatory bowel diseases, allergies, and diabetes. In this review, we discuss the most promising application possibilities for immunomodulatory protein hydrolysates, based on the current knowledge on in vivo immune effects of protein hydrolysates, and the current insights in the underlying mechanisms of these effects. View this paper