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Pediatric Reports, Volume 13, Issue 3

2021 September - 23 articles

Cover Story: Drawing on a well-disputed Cochrane Review from 2015 assessing methylphenidate for children and adolescents with ADHD, this viewpoint examines systematic reviews and meta-analyses published since then. The quality of the evidence is assessed with AMSTAR 2 (a measurement tool to assess the quality of systematic reviews). While there is an excess of systematic reviews and meta-analyses available on this topic, relatively few are of high quality according to AMSTAR 2. Additionally, there is very little mention of adverse effects associated with methylphenidate. While acknowledging that some experience beneficial effects of treatment, this viewpoint discusses the balance between benefits and harms of methylphenidate for children and adolescents with ADHD as well as points out the knowledge gap on long-term treatment effects. View this paper
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Articles (23)

  • Brief Report
  • Open Access
22 Citations
11,718 Views
7 Pages

14 September 2021

While we know that the pandemic and its social isolation, loss of school experiences, increased screen use, and financial stress have likely had a psychological impact upon children and teens, little research has been done directly with youth to asse...

  • Article
  • Open Access
4 Citations
4,181 Views
8 Pages

Childhood Obesity and Maternal Personality Traits: A New Point of View on Obesity Behavioural Aspects

  • Francesco Precenzano,
  • Daniela Smirni,
  • Luigi Vetri,
  • Pierluigi Marzuillo,
  • Valentina Lanzara,
  • Ilaria Bitetti,
  • Margherita Siciliano,
  • Emanuele Miraglia del Giudice,
  • Maria Esposito and
  • Marco Carotenuto
  • + 1 author

1 September 2021

The epidemic spread of childhood obesity in Western society has interested many researchers, who agree in defining it as a multifactorial disease in which not only eating habits and sedentary lifestyle play a role, but also genetic predisposition. Th...

  • Case Report
  • Open Access
5 Citations
3,964 Views
7 Pages

Brugada Pattern in a Child with Severe SARS-CoV-2 Related Multisystem Inflammatory Syndrome

  • Angelica De Nigris,
  • Angela Pepe,
  • Giangiacomo Di Nardo,
  • Antonietta Giannattasio,
  • Annamaria Pagano,
  • Carolina D’Anna,
  • Stefania Muzzica,
  • Selvaggia Lenta,
  • Giovanni Maria Di Marco and
  • Vincenzo Tipo

1 September 2021

This report presents the first case of Brugada pattern complicated by a supraventricular arrhythmia in a child with SARS-CoV-2 related Multisystem Inflammatory Syndrome in Children (MIS-C). A 7-year-old boy came to our Emergency Department with 7 day...

  • Case Report
  • Open Access
3 Citations
4,429 Views
9 Pages

1 September 2021

Every year, there are over 3300 ingestions of button batteries, mostly by young children. Initial presentation of button battery ingestion may be nonspecific, with a delay in diagnosis and removal resulting in increased risk of complications. We pres...

  • Article
  • Open Access
5 Citations
3,865 Views
10 Pages

Comparison of Sympathetic Skin Response (SSR) between Electrical and Acoustic Stimuli in a Healthy Pediatric Population

  • Sara Cavaliere,
  • Giovanna Bertini,
  • Cesarina Cossu,
  • Maria Bastianelli,
  • Simonetta Gabbanini,
  • Cristina Mei and
  • Silvia Lori

1 September 2021

Data in the literature report that latency and morphology in the cutaneous sympathetic skin response (SSR) do not change according to the type of stimulus delivered, unlike the amplitude which shows greater values in relation to the intensity of the...

  • Opinion
  • Open Access
21 Citations
22,760 Views
4 Pages

COVID 19 Vaccine for Adolescents. Concern about Myocarditis and Pericarditis

  • Giuseppe Calcaterra,
  • Jawahar Lal Mehta,
  • Cesare de Gregorio,
  • Gianfranco Butera,
  • Paola Neroni,
  • Vassilios Fanos and
  • Pier Paolo Bassareo

1 September 2021

The alarming onset of some cases of myocarditis and pericarditis following the administration of Pfizer–BioNTech and Moderna COVID-19 mRNA-based vaccines in adolescent males has recently been highlighted. All occurred after the second dose of the vac...

  • Case Report
  • Open Access
3,446 Views
4 Pages

Acute Hepatitis B and Unusual Follow-Up in a 16-Year-Old Boy: Case Report

  • Carlo Bieńkowski,
  • Monika Kowalczyk,
  • Magdalena Pluta and
  • Maria Pokorska-Śpiewak

1 September 2021

In this case report, we present a 16-year-old Ukrainian boy with acute hepatitis B. He had not been previously vaccinated against hepatitis B. Possible sources of infection included: a tattoo made at home, a finger cut made with hairdresser scissors...

  • Article
  • Open Access
1 Citations
3,265 Views
9 Pages

10 August 2021

Background: There are non-invasive methods of correcting genu valgum (GV), but to date, there is no method to evaluate mechanotherapeutic intervention that does not restrict child’s natural movements while the process is on-going so that timely decis...

  • Article
  • Open Access
6 Citations
22,039 Views
5 Pages

9 August 2021

Background: Perineal groove is a very rare congenital malformation that usually occurs in females. It has been described as a wet, un-epithelialized mucus tissue extending from the posterior vaginal fourchette to the anterior anal opening. It is gene...

  • Case Report
  • Open Access
4 Citations
2,463 Views
7 Pages

7 August 2021

Common variable immunodeficiency (CVID) is a primary immune deficit (PID) mainly characterized by hypogammaglobulinemia. In addition to increased susceptibility to infections and several immune-mediated manifestations, patients with CVID frequently d...

  • Article
  • Open Access
5 Citations
2,862 Views
13 Pages

Gallbladder Interleukins in Children with Calculous Cholecystitis

  • Arina Deņisova,
  • Māra Pilmane,
  • Arnis Eņģelis and
  • Aigars Pētersons

5 August 2021

Calculous cholecystitis connects to inflammation and various complications. It is a common disease in the paediatric population, yet it is still uncertain how inflammation factors are involved in its morphopathogenesis. Twenty calculous cholecystitis...

  • Case Report
  • Open Access
3,714 Views
7 Pages

4 August 2021

Background: Anemia is common in patients with nephrotic syndrome (NS) for various reasons. Furthermore, anemia can occur in patients with chronic kidney disease (CKD) predominantly owing to inappropriately low erythropoietin (EPO) production relative...

  • Article
  • Open Access
3 Citations
4,346 Views
13 Pages

3 August 2021

Background: Attention deficit hyperactivity disorder is the most common childhood psychiatric disorder. Current treatment strategies do not provide a convincing improvement on overall functioning, and further, reciprocity between ADHD and attachment...

  • Viewpoint
  • Open Access
10 Citations
13,439 Views
10 Pages

Does Methylphenidate Work in Children and Adolescents with Attention Deficit Hyperactivity Disorder?

  • Johanne Pereira Ribeiro,
  • Emma Jasmine Arthur,
  • Christian Gluud,
  • Erik Simonsen and
  • Ole Jakob Storebø

1 August 2021

Objective: Attention deficit hyperactivity disorder (ADHD) is a common psychiatric disorder diagnosed in increasing proportions of children and adolescents. The psychostimulant methylphenidate has been considered the first-line pharmacological treatm...

  • Case Report
  • Open Access
10 Citations
7,165 Views
6 Pages

Acquired Zinc Deficiency Mimicking Acrodermatitis Enteropathica in a Breast-Fed Premature Infant

  • Giovanna D’Amico,
  • Corinne De Laet,
  • Guillaume Smits,
  • Deborah Salik,
  • Guillaume Deprez,
  • Catheline Vilain,
  • Pascale Perlot and
  • Alfredo Vicinanza

1 August 2021

We present a case of a transient acquired zinc deficiency in a breast-fed, 4-month-old-male prematurely born infant, with acrodermatitis enteropathica-like symptoms such as crusted, eroded, erythemato-squamous eruption in periorificial and acral patt...

  • Article
  • Open Access
11 Citations
5,175 Views
13 Pages

The Utility of Pharmacogenetic-Guided Psychotropic Medication Selection for Pediatric Patients: A Retrospective Study

  • Merlin Ariefdjohan,
  • Yee Ming Lee,
  • Danielle L. Stutzman,
  • Sean LeNoue and
  • Marianne Z. Wamboldt

28 July 2021

Background: To describe trends and clinical experiences in applying commercial pharmacogenetic testing among pediatric patients with neuropsychiatric disorders. Methods: Demographic and clinical data of patients receiving GeneSight® testing from Janu...

  • Case Report
  • Open Access
7 Citations
3,004 Views
5 Pages

IgA Vasculitis Complicated by Both CMV Reactivation and Tuberculosis

  • Małgorzata Mizerska-Wasiak,
  • Maria Winiarska,
  • Karolina Nogal,
  • Karolina Cichoń-Kawa,
  • Małgorzata Pańczyk-Tomaszewska and
  • Jadwiga Małdyk

22 July 2021

Immunoglobulin A (IgA) vasculitis is the most common systemic vasculitis in the pediatric population. We present the case of a patient with IgA vasculitis with nephritis who developed cytomegalovirus (CMV) infection followed by Mycobacterium tubercul...

  • Review
  • Open Access
31 Citations
36,379 Views
15 Pages

14 July 2021

A growing number of children and adolescents play video games (VGs) for long amounts of time. The current outbreak of the Coronavirus pandemic has significantly reduced outdoor activities and direct interpersonal relationships. Therefore, a higher us...

  • Article
  • Open Access
10 Citations
4,693 Views
18 Pages

Oncological Children and Well-Being: Occupational Performance and HRQOL Change after Fine Motor Skills Stimulation Activities

  • Livia Taverna,
  • Martina Bellavere,
  • Marta Tremolada,
  • Lietta Santinelli,
  • Nicola Rudelli,
  • Michele Mainardi,
  • Graziano Onder,
  • Maria Caterina Putti,
  • Alessandra Biffi and
  • Barbara Tosetto

Cancer children experience long periods of hospitalization, which are associated with limited performance in several developmental domains and participation restrictions in age appropriate occupations. Fine motor abilities represent building blocks i...

  • Review
  • Open Access
28 Citations
6,227 Views
20 Pages

Innate Immunity in Children and the Role of ACE2 Expression in SARS-CoV-2 Infection

  • Mario Dioguardi,
  • Angela Pia Cazzolla,
  • Claudia Arena,
  • Diego Sovereto,
  • Giorgia Apollonia Caloro,
  • Antonio Dioguardi,
  • Vito Crincoli,
  • Luigi Laino,
  • Giuseppe Troiano and
  • Lorenzo Lo Muzio

COVID-19 (Coronavirus Disease 2019) is an emerging viral disease caused by the coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which leads to severe respiratory infections in humans. The first reports came in December 2019 f...

  • Communication
  • Open Access
7 Citations
3,127 Views
7 Pages

Metabolically Unhealthy Phenotype: A Key Factor in Determining “Pediatric” Frailty

  • Valeria Calcaterra,
  • Hellas Cena,
  • Annamaria Ruggieri,
  • Gianvincenzo Zuccotti,
  • Annalisa De Silvestri,
  • Gianni Bonalumi and
  • Gloria Pelizzo

Frailty (FI) and metabolic syndrome (MS) are each associated with adverse health outcomes. A relationship between FI and MS has previously been described in adults. We considered the prevalence of a metabolically unhealthy phenotype (MUP) in malnouri...

  • Case Report
  • Open Access
7 Citations
5,535 Views
10 Pages

Safe and Effective Treatment of Intracranial Infantile Hemangiomas with Beta-Blockers

  • Aoife Naughton,
  • Ariel Yuhan Ong and
  • Goran Darius Hildebrand

Infantile hemangiomas are common benign vascular tumors but are rarely found in an intracranial location. Our literature review identified 41 reported cases. There is no general consensus on management of these rare lesions and until recently, treatm...

  • Case Report
  • Open Access
3 Citations
3,786 Views
6 Pages

Atypically Protracted Course of Liver Involvement in Kawasaki Disease. Case Report and Literature Review

  • Pamela Paglia,
  • Lucia Nazzaro,
  • Anna Giulia Elena De Anseris,
  • Milena Lettieri,
  • Rossella Colantuono,
  • Maria Chiara Rocco,
  • Maria Anna Siano,
  • Nicola Biffaro and
  • Pietro VAJRO

Hypertransaminasemia in patients with Kawasaki disease (KD) is reported to be transient. Here, we describe a child with an atypically protracted course of liver tests abnormalities and review the inherent literature. The patient was hospitalized at a...

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Pediatr. Rep. - ISSN 2036-7503