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Pathophysiology, Volume 30, Issue 2

June 2023 - 15 articles

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Articles (15)

  • Article
  • Open Access
3 Citations
2,523 Views
15 Pages

Elevated Levels of Serum Biomarkers Associated with Damage to the CNS Neurons and Endothelial Cells Are Linked with Changes in Brain Connectivity in Breast Cancer Patients with Vestibulo-Atactic Syndrome

  • Alexandra Nikolaeva,
  • Maria Pospelova,
  • Varvara Krasnikova,
  • Albina Makhanova,
  • Samvel Tonyan,
  • Yurii Krasnopeev,
  • Evgeniya Kayumova,
  • Elena Vasilieva,
  • Aleksandr Efimtsev and
  • Anatoliy Levchuk
  • + 3 authors

Vestibulo-atactic syndrome (VAS), which represents a combination of motor and vestibular disorders, can be manifested as a clinical complication of breast cancer treatment and has a significant impact on patients’ quality of life. The identific...

  • Article
  • Open Access
1,855 Views
12 Pages

Antioxidant protection is one of the key reactions of cardiomyocytes (CMCs) in response to myocardial damage of various origins. The thioredoxin interacting protein (TXNIP) is an inhibitor of thioredoxin (TXN). Over the recent few years, TXNIP has re...

  • Systematic Review
  • Open Access
12 Citations
4,392 Views
15 Pages

Risk Factors and Clinical Characteristics of Acute Kidney Injury in Patients with COVID-19: A Systematic Review and Meta-Analysis

  • Amal Arifi Hidayat,
  • Vania Azalia Gunawan,
  • Firda Rachmawati Iragama,
  • Rizky Alfiansyah,
  • Decsa Medika Hertanto,
  • Artaria Tjempakasari and
  • Mochammad Thaha

Acute kidney injury (AKI) is associated with a worse prognosis in coronavirus disease 2019 (COVID-19) patients. Identification of AKI, particularly in COVID-19 patients, is important for improving patients’ management. The study aims to assess...

  • Article
  • Open Access
2 Citations
2,410 Views
14 Pages

Trends in Drug Tests among Children: A 22-Year Retrospective Analysis

  • Carolina Ochoa,
  • Phillip C. S. R. Kilgore,
  • Nadejda Korneeva,
  • Eric Clifford,
  • Steven A. Conrad,
  • Marjan Trutschl,
  • Jacquelyn M. Bowers,
  • Thomas Arnold and
  • Urska Cvek

There are several pathophysiological outcomes associated with substance abuse including metabolic disbalance, neurodegeneration, and disordered redox. Drug use in pregnant women is a topic of great concern due to developmental harm which may occur du...

  • Article
  • Open Access
1,954 Views
10 Pages

Cerebral Circulation and Brain Temperature during an Ultra-Short Session of Dry Immersion in Young Subjects

  • Liudmila Gerasimova-Meigal,
  • Alexander Meigal,
  • Maria Gerasimova,
  • Anna Sklyarova and
  • Ekaterina Sirotinina

The primary aim of the study was to assess cerebral circulation in healthy young subjects during an ultra-short (45 min) session of ground-based microgravity modeled by “dry” immersion (DI), with the help of a multifunctional Laser Dopple...

  • Article
  • Open Access
6 Citations
3,517 Views
10 Pages

In addition to mandibular advancement devices, dental expansion appliances are an important clinical approach for achieving an increased intra-oral space that promotes airflow and lessens the frequency or severity of apneic events in patients diagnos...

  • Article
  • Open Access
11 Citations
3,191 Views
13 Pages

Duration of SARS-CoV-2 RNA Shedding Is Significantly Influenced by Disease Severity, Bilateral Pulmonary Infiltrates, Antibiotic Treatment, and Diabetic Status: Consideration for Isolation Period

  • Muhammad Vitanata Arfijanto,
  • Tri Pudy Asmarawati,
  • Bramantono Bramantono,
  • Musofa Rusli,
  • Brian Eka Rachman,
  • Bagus Aulia Mahdi,
  • Nasronudin Nasronudin and
  • Usman Hadi

Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) ribonucleic acid (RNA) shedding is an important parameter for determining the optimal length of isolation period required for coronavirus disease 2019 (COVID-19) patients. However, the...

  • Article
  • Open Access
3 Citations
2,318 Views
12 Pages

Advantages of Multiposition Scanning in Echocardiographic Assessment of the Severity of Discordant Aortic Stenosis

  • Elena Zelikovna Golukhova,
  • Inessa Viktorovna Slivneva,
  • Inga Yur’evna Farulova,
  • Ivan Ivanovich Skopin,
  • Damir Ildarovich Marapov,
  • Dar’ya Vladimirovna Murysova,
  • Yuliya Dmitrievna Pirushkina and
  • Irina Vasilyevna Volkovskaya

Aim of the study: The aim of this study was to perform a comparative analysis of severity of discordant aortic stenosis (AS) assessment using multiposition scanning and the standard apical window. Materials and Methods: All patients (n = 104) underwe...

  • Review
  • Open Access
29 Citations
13,188 Views
19 Pages

In recent years, the elderly has become a rapidly growing proportion of the world’s population as life expectancy is extending. Immunosenescence and inflammaging contribute to the increased risk of chronic non-communicable and acute infectious...

  • Article
  • Open Access
4,165 Views
11 Pages

Methamphetamine and Designer Stimulants Modulate Tonic Human Cerebrovascular Smooth Muscle Contractility: Relevance to Drug-Induced Neurovascular Stress

  • Nicole Hall,
  • Nhi Dao,
  • Cameron Hewett,
  • Sara Oberle,
  • Andrew Minagar,
  • Kariann Lamon,
  • Carey Ford,
  • Bruce E. Blough,
  • J. Steven Alexander and
  • Kevin S. Murnane

To avoid criminal prosecution, clandestine chemists produce designer stimulants that mimic the pharmacological and psychoactive effects of conventional stimulants, such as methamphetamine. Following persistent or high-dose exposure, both acute vasoco...

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