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Marine Drugs, Volume 20, Issue 12

December 2022 - 61 articles

Cover Story: Marine macroalgae (seaweeds) are considered an untapped source of healthy natural metabolites, and their market demand is rapidly increasing. In order to thrive under changing environmental conditions, intertidal macroalgae have developed chemical defense mechanisms, including the synthesis of a wide variety of unique bioactive compounds that can be used for human benefit. We present an original two-phase multitrophic aquaculture system, designed to direct seaweed metabolic responses to enhance the production of target antioxidant and photoprotective biomaterials. Our integrated cultivation plan offers a sustainable approach, with the potential to be adopted by emerging industries for food and health applications. View this paper
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Articles (61)

  • Review
  • Open Access
31 Citations
4,259 Views
22 Pages

Macroalgae Specialized Metabolites: Evidence for Their Anti-Inflammatory Health Benefits

  • Djenisa H. A. Rocha,
  • Diana C. G. A. Pinto and
  • Artur M. S. Silva

19 December 2022

Inflammation is an organism’s response to chemical or physical injury. It is split into acute and chronic inflammation and is the last, most significant cause of death worldwide. Nowadays, according to the World Health Organization (WHO), the g...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,223 Views
15 Pages

Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads

  • Justin M. McNab,
  • Matthew T. Briggs,
  • Jane E. Williamson,
  • Peter Hoffmann,
  • Jorge Rodriguez and
  • Peter Karuso

19 December 2022

Tetrodotoxin (TTX) is a potent marine neurotoxin that occurs in several Australian phyla, including pufferfish, toadfish, gobies, and the blue-ringed octopus. These animals are partially immune, and TTX is known to bioaccumulate and subject to trophi...

  • Article
  • Open Access
5 Citations
5,238 Views
18 Pages

Complexes of Cu–Polysaccharide of a Marine Red Microalga Produce Spikes with Antimicrobial Activity

  • Nofar Yehuda,
  • Levi A. Gheber,
  • Ariel Kushmaro and
  • Shoshana (Mails) Arad

19 December 2022

Metal–polysaccharides have recently raised significant interest due to their multifunctional bioactivities. The antimicrobial activity of a complex of Cu2O with the sulfated polysaccharide (PS) of the marine red microalga Porphyridium sp. was p...

  • Article
  • Open Access
17 Citations
3,539 Views
18 Pages

Polyphenolic Compounds Isolated from Marine Algae Attenuate the Replication of SARS-CoV-2 in the Host Cell through a Multi-Target Approach of 3CLpro and PLpro

  • D. P. Nagahawatta,
  • N. M. Liyanage,
  • Jun-Geon Je,
  • H. H. A. C. K. Jayawardhana,
  • Thilina U. Jayawardena,
  • Seong-Hun Jeong,
  • Hyung-Jun Kwon,
  • Cheol Soo Choi and
  • You-Jin Jeon

19 December 2022

A global health concern has emerged as a response to the recent SARS-CoV-2 pandemic. The identification and inhibition of drug targets of SARS-CoV-2 is a decisive obligation of scientists. In addition to the cell entry mechanism, SARS-CoV-2 expresses...

  • Article
  • Open Access
12 Citations
4,919 Views
16 Pages

Fillet Fish Fortified with Algal Extracts of Codium tomentosum and Actinotrichia fragilis, as a Potential Antibacterial and Antioxidant Food Supplement

  • Mohamed S. M. Abd El Hafez,
  • Sarah H. Rashedy,
  • Neveen M. Abdelmotilib,
  • Hala E. Abou El-Hassayeb,
  • João Cotas and
  • Leonel Pereira

17 December 2022

With respect to the potential natural resources in the marine environment, marine macroalgae or seaweeds are recognized to have health impacts. Two marine algae that are found in the Red Sea, Codium tomentosum (Green algae) and Actinotrichia fragilis...

  • Review
  • Open Access
43 Citations
5,441 Views
16 Pages

Antidiabetic Properties of Chitosan and Its Derivatives

  • Huei-Ping Tzeng,
  • Shing-Hwa Liu and
  • Meng-Tsan Chiang

17 December 2022

Diabetes mellitus is a chronic metabolic disorder. In addition to taking medication, adjusting the composition of the diet is also considered one of the effective methods to control the levels of blood glucose. Chitosan and its derivatives are natura...

  • Article
  • Open Access
12 Citations
3,032 Views
13 Pages

A Novel κ-Carrageenase from Marine Bacterium Rhodopirellula sallentina SM41: Heterologous Expression, Biochemical Characterization and Salt-Tolerance Mechanism Investigation

  • Yong-Hui Zhang,
  • Yi-Ying Chen,
  • Xiao-Yan Zhuang,
  • Qiong Xiao,
  • Jun Chen,
  • Fu-Quan Chen,
  • Qiu-Ming Yang,
  • Hui-Fen Weng,
  • Bai-Shan Fang and
  • An-Feng Xiao

16 December 2022

κ-carrageenases are members of the glycoside hydrolase family 16 (GH16) that hydrolyze sulfated galactans in red algae, known as κ-carrageenans. In this study, a novel κ-carrageenase gene from the marine bacterium Rhodopirellula sal...

  • Feature Paper
  • Review
  • Open Access
29 Citations
5,719 Views
14 Pages

Chitosan-Based Carbon Dots with Applied Aspects: New Frontiers of International Interest in a Material of Marine Origin

  • Angel M. Villalba-Rodríguez,
  • Reyna Berenice González-González,
  • Manuel Martínez-Ruiz,
  • Elda A. Flores-Contreras,
  • María Fernanda Cárdenas-Alcaide,
  • Hafiz M. N. Iqbal and
  • Roberto Parra-Saldívar

16 December 2022

Carbon dots (CDs) have attracted significant research attention worldwide due to their unique properties and advantageous attributes, such as superior optical properties, biocompatibility, easy surface functionalization, and more. Moreover, biomass-d...

  • Article
  • Open Access
27 Citations
6,386 Views
13 Pages

Functional Properties of Dunaliella salina and Its Positive Effect on Probiotics

  • Ivana Hyrslova,
  • Gabriela Krausova,
  • Iva Mrvikova,
  • Barbora Stankova,
  • Tomas Branyik,
  • Hana Malinska,
  • Martina Huttl,
  • Antonin Kana and
  • Ivo Doskocil

15 December 2022

The unicellular green microalga Dunaliella is a potential source of a wide range of nutritionally important compounds applicable to the food industry. The aim of this study was to assess the effect of Dunaliella salina dried biomass on the growth and...

  • Article
  • Open Access
10 Citations
3,854 Views
26 Pages

14 December 2022

Aurantiochytrium is a heterotrophic marine microalga that has potential industrial applications. The main objectives of this study were to isolate an Aurantiochytrium strain from Sand Cay (Son Ca) Island, Vietnam, optimize its culture conditions, det...

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Mar. Drugs - ISSN 1660-3397