Topic Editors

Dr. Barbara De Filippis
Department of Pharmacy, University of G. d'Annunzio Chieti and Pescara, Chieti, Italy
Dr. Alessandra Ammazzalorso
Dipartimento di Farmacia, University of G. d'Annunzio Chieti and Pescara, Chieti, Italy
Dr. Marialuigia Fantacuzzi
Department of Pharmacy, University G. d’Annunzio of Chieti-Pescara, Via dei Vestini, 31, 66100 Chieti, Italy

Antitumor Activity of Natural Products and Related Compounds

Abstract submission deadline
31 May 2023
Manuscript submission deadline
31 August 2023
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Topic Information

Dear Colleagues,

Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is an ongoing effort.

Nature provides a wide range of compounds with a great variety of chemical scaffolds and distinct bioactivity profiles. Indeed, natural products are a rich source of bioactive molecules that, over the years, have found application in the treatment of many diseases, including cancer. Natural products have played an important role in chemotherapy and chemoprevention by providing antitumor drugs such as camptothecin, doxorubicin, paclitaxel, vinblastine, and vincristine, as well as understanding the cellular and molecular mechanisms underlying antitumor activity. Significant advances in natural source isolation and extraction techniques have enabled the identification of novel lead compounds as useful starting points for the generation of optimized molecules with enhanced therapeutic potential via semi-synthetic or synthetic processes.

The focus of this Topic is on natural substances derived from plants or animals, as well as their synthetic derivatives, which have been investigated for their ability to counteract cancer progression.

Dr. Barbara De Filippis
Dr. Alessandra Ammazzalorso
Dr. Marialuigia Fantacuzzi
Topic Editors


  • anticancer
  • antiproliferation
  • natural compounds
  • natural derivatives
  • drug discovery
  • bioactive natural products
  • synthetic compounds
  • medicinal chemistry
  • computational chemistry
  • biological activity
  • structure–activity relationship
  • structure-based drug design
  • target identification and validation

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
6.064 5.7 2011 15.8 Days 2100 CHF Submit
International Journal of Molecular Sciences
6.208 6.9 2000 15.9 Days 2300 CHF Submit
4.927 5.9 1996 14.2 Days 2300 CHF Submit
Scientia Pharmaceutica
- 5.3 1930 27.9 Days 1000 CHF Submit
6.575 5.8 2009 17.4 Days 2400 CHF Submit
Marine Drugs
6.085 8.1 2003 12.6 Days 2400 CHF Submit

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Published Papers

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