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Marine Drugs, Volume 19, Issue 7

2021 July - 51 articles

Cover Story: An extract of Astrosclera willeyana, a calcareous demosponge, was selected for chemical study since it inhibited the ubiquitin ligase activity of the immunomodulatory protein, Cbl-b. Six bromopyrrole alkaloids from the ageliferin family, along with four N-methyladenine-containing agelasine diterpenoids, were subsequently isolated and identified by spectroscopic means. All of the isolated compounds had Cbl-b inhibitory activities, and four had new structures. View this paper
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Articles (51)

  • Article
  • Open Access
46 Citations
4,216 Views
18 Pages

MMP-9 and IL-1β as Targets for Diatoxanthin and Related Microalgal Pigments: Potential Chemopreventive and Photoprotective Agents

  • Luigi Pistelli,
  • Clementina Sansone,
  • Arianna Smerilli,
  • Marco Festa,
  • Douglas M. Noonan,
  • Adriana Albini and
  • Christophe Brunet

22 June 2021

Photochemoprevention can be a valuable approach to counteract the damaging effects of environmental stressors (e.g., UV radiations) on the skin. Pigments are bioactive molecules, greatly attractive for biotechnological purposes, and with promising ap...

(This article belongs to the Special Issue Antiphotoaging and Photoprotective Compounds from Marine Organisms)

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Mar. Drugs - ISSN 1660-3397