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Marine Drugs, Volume 19, Issue 6

June 2021 - 69 articles

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Cover Story: The Mariana Trench sediment strain Dermacoccus abyssi MT1.1T is known to produce novel phenazines called dermacozines. In our recent article alongside the compound isolation of the unprecedented dermacozine N and the new dermacozines O and P, we describe their challenging structure elucidation arising from their polycyclic nature being supported with various statistical and computational chemistry methods. The example of the dermacozines shows, that despite the mesmerizing depth of the hadal zone a vividly coloured life is thriving there. The vast majority of natural products—with potential applications from opto-electronics through biosensing chemistry up to medicinal chemistry—so far have not yet been explored. View this paper

Articles (69)

  • Review
  • Open Access
15 Citations
4,836 Views
22 Pages

Microbial Oligosaccharides with Biomedical Applications

  • Jian-Lin Xu,
  • Zhi-Feng Liu,
  • Xiao-Wei Zhang,
  • Hai-Li Liu and
  • Yong Wang

21 June 2021

Microbial oligosaccharides have been regarded as one of the most appealing natural products attributable to their potent and selective bioactivities, such as antimicrobial activity, inhibition of α-glucosidases and lipase, interference of cellular re...

  • Article
  • Open Access
12 Citations
3,829 Views
14 Pages

Distribution of the Water-Soluble Astaxanthin Binding Carotenoprotein (AstaP) in Scenedesmaceae

  • Hiroki Toyoshima,
  • Ami Miyata,
  • Risako Yoshida,
  • Taichiro Ishige,
  • Shinichi Takaichi and
  • Shinji Kawasaki

20 June 2021

Photooxidative stress-inducible water-soluble astaxanthin-binding proteins, designated as AstaP, were identified in two Scenedesmaceae strains, Coelastrella astaxanthina Ki-4 and Scenedesmus obtusus Oki-4N; both strains were isolated under high light...

  • Article
  • Open Access
16 Citations
2,938 Views
10 Pages

19 June 2021

Four new chromones, phomochromenones D–G (1–4), along with four known analogues, diaporchromone A (5), diaporchromanone C (6), diaporchromanone D (7), and phomochromenone C (8), were isolated from the culture of Phomopsis asparagi DHS-48 from Chinese...

  • Article
  • Open Access
33 Citations
4,307 Views
16 Pages

Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction

  • Yinyan Yin,
  • Nuo Xu,
  • Yi Shi,
  • Bangyue Zhou,
  • Dongrui Sun,
  • Bixia Ma,
  • Zhengzhong Xu,
  • Jin Yang and
  • Chunmei Li

17 June 2021

Astaxanthin, originating from seafood, is a naturally occurring red carotenoid pigment. Previous studies have focused on its antioxidant properties; however, whether astaxanthin possesses a desired anti-inflammatory characteristic to regulate the den...

  • Article
  • Open Access
62 Citations
4,905 Views
18 Pages

17 June 2021

For utilizing the largest source of marine proteins, Antarctic krill (Euphausia superba) proteins were defatted and hydrolyzed separately using pepsin, alcalase, papain, trypsin, and netrase, and alcalase hydrolysate (EPAH) showed the highest DPPH ra...

  • Article
  • Open Access
29 Citations
4,988 Views
24 Pages

Agarose Stearate-Carbomer940 as Stabilizer and Rheology Modifier for Surfactant-Free Cosmetic Formulations

  • Qiong Xiao,
  • Guo Chen,
  • Yong-Hui Zhang,
  • Fu-Quan Chen,
  • Hui-Fen Weng and
  • An-Feng Xiao

16 June 2021

Some commonly used surfactants in cosmetic products raise concerns due to their skin-irritating effects and environmental contamination. Multifunctional, high-performance polymers are good alternatives to overcome these problems. In this study, agaro...

  • Review
  • Open Access
19 Citations
5,544 Views
21 Pages

Bridging Cyanobacteria to Neurodegenerative Diseases: A New Potential Source of Bioactive Compounds against Alzheimer’s Disease

  • Andrea Castaneda,
  • Ricardo Ferraz,
  • Mónica Vieira,
  • Isabel Cardoso,
  • Vitor Vasconcelos and
  • Rosário Martins

16 June 2021

Neurodegenerative diseases (NDs) represent a drawback in society given the ageing population. Dementias are the most prevalent NDs, with Alzheimer’s disease (AD) representing around 70% of all cases. The current pharmaceuticals for AD are symptomatic...

  • Review
  • Open Access
77 Citations
7,792 Views
15 Pages

16 June 2021

Marine biomass is a treasure trove of materials. Marine polysaccharides have the characteristics of biocompatibility, biodegradability, non-toxicity, low cost, and abundance. An enormous variety of polysaccharides can be extracted from marine organis...

  • Review
  • Open Access
118 Citations
17,083 Views
24 Pages

An Overview to the Health Benefits of Seaweeds Consumption

  • Silvia Lomartire,
  • João Carlos Marques and
  • Ana M. M. Gonçalves

15 June 2021

Currently, seaweeds are gaining major attention due to the benefits they give to our health. Recent studies demonstrate the high nutritional value of seaweeds and the powerful properties that seaweeds’ bioactive compounds provide. Species of class Ph...

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Mar. Drugs - ISSN 1660-3397Creative Common CC BY license