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Review

Microbial Oligosaccharides with Biomedical Applications

by 1,2,3,†, 1,2,†, 1, 1,* and 1,*
1
Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China
2
University of Chinese Academy of Sciences, Beijing 100039, China
3
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Hitoshi Sashiwa
Mar. Drugs 2021, 19(6), 350; https://doi.org/10.3390/md19060350
Received: 21 May 2021 / Revised: 9 June 2021 / Accepted: 16 June 2021 / Published: 21 June 2021
Microbial oligosaccharides have been regarded as one of the most appealing natural products attributable to their potent and selective bioactivities, such as antimicrobial activity, inhibition of α-glucosidases and lipase, interference of cellular recognition and signal transduction, and disruption of cell wall biosynthesis. Accordingly, a handful of bioactive oligosaccharides have been developed for the treatment of bacterial infections and type II diabetes mellitus. Given that naturally occurring oligosaccharides have increasingly gained recognition in recent years, a comprehensive review is needed. The current review highlights the chemical structures, biological activities and divergent biosynthetic origins of three subgroups of oligomers including the acarviosine-containing oligosaccharides, saccharomicins, and orthosomycins. View Full-Text
Keywords: microbial oligosaccharide; aminooligosaccharide; saccharomicin; orthosomycin; chemical structure; biomedical applications; biosynthesis microbial oligosaccharide; aminooligosaccharide; saccharomicin; orthosomycin; chemical structure; biomedical applications; biosynthesis
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MDPI and ACS Style

Xu, J.-L.; Liu, Z.-F.; Zhang, X.-W.; Liu, H.-L.; Wang, Y. Microbial Oligosaccharides with Biomedical Applications. Mar. Drugs 2021, 19, 350. https://doi.org/10.3390/md19060350

AMA Style

Xu J-L, Liu Z-F, Zhang X-W, Liu H-L, Wang Y. Microbial Oligosaccharides with Biomedical Applications. Marine Drugs. 2021; 19(6):350. https://doi.org/10.3390/md19060350

Chicago/Turabian Style

Xu, Jian-Lin, Zhi-Feng Liu, Xiao-Wei Zhang, Hai-Li Liu, and Yong Wang. 2021. "Microbial Oligosaccharides with Biomedical Applications" Marine Drugs 19, no. 6: 350. https://doi.org/10.3390/md19060350

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