Special Issue "Marine Biotoxins"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (16 October 2021).
Interests: natural toxins from marine and terrestrial organisms; voltage-gated ion channels; nicotinic acetylcholine receptors; cholinesterases; IP3 receptors; cell signaling; synaptic transmission
Special Issues and Collections in MDPI journals
Special Issue in Molecules: Natural Bioactive Molecules and Toxins from Marine and Terrestrial Origin
Marine environments are known to contain microorganisms such as bacteria, cyanobacteria, dinoflagellates, diatoms, and fungi. When environmental conditions are favorable for their massive proliferation (increase in temperature, richness in nutrients, salinity, luminosity, etc.), these unicellular microorganisms may manifest their potential toxicity by producing marine biotoxins and contaminating invertebrate and vertebrate marine organisms through the food web. Undeniably, these marine biotoxins may constitute a risk for human consumers of contaminated shellfish and fish. Also, the vectorial transfer of marine biotoxins to crabs, fish, birds, and marine mammals constitutes a menace for wildlife. Most marine biotoxins belong to different families of organic molecules, with diverse and rich chemical structures, and new marine biotoxins of organic and protein nature are being described. The vast family of marine biotoxins act on different targets including subtypes of voltage-gated sodium ion channels, potassium or calcium channels, ionotropic receptors—like glutamate receptors (AMPA, Kainate, and NMDA receptors), nicotinic acetylcholine receptors, γ-aminobutyric acid (GABAA receptors)—and G protein-coupled receptors. Therefore, important efforts are being made to decipher the cellular and molecular signaling pathways used by marine biotoxins to exert their toxic activity.
This special issue of Marine Drugs is open to original research articles and reviews dealing with marine biotoxins and the following subjects:
- Identification of new and emergent marine biotoxins
- Marine biotoxins from identified bacteria, cyanobacteria, fungi, dinoflagellates, and diatoms
- Characterization of new biotoxin chemical structures
- Biosynthetic pathways involved in biotoxin production
- Cellular and molecular signaling pathways implicated in marine biotoxin action
- Pharmacology and structure–activity relationship
- Bio-distribution, metabolism, acute and chronic toxicity in animal models
- Molecular modeling of marine biotoxins with their putative receptors
- Potential therapeutic uses of marine biotoxins
Prof. Dr. Jordi Molgó
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Marine biotoxins
- Molecular target(s)
- Signaling pathways
- Molecular modeling
- Therapeutic potential