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Marine Drugs, Volume 17, Issue 1

January 2019 - 72 articles

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Cover Story: Novel methods were tested to culture the collagen-rich sponge Chondrosia reniformis in the proximity of floating fish cages. Attachment methods, plate materials, and plate orientation were compared. After three consecutive experiments, a culture protocol was established resulting in 86% survival and 170% growth for C. reniformis. Survival and growth of cultured explants near the fish farm polluted with organic waste was almost twice that at the pristine control site. This successful step towards production of sponge collagen in integrated aquacultures also reveals C. reniformis as a potential candidate for bioremediation of waters polluted with organic waste. View this paper.

Articles (72)

  • Article
  • Open Access
5 Citations
4,120 Views
13 Pages

21 January 2019

Chitooligosaccharides (CHOS) have gained increasing attention because of their important biological activities. Enhancing the efficiency of CHOS production essentially requires screening of novel chitosanase with unique characteristics. Therefore, a...

  • Article
  • Open Access
35 Citations
7,126 Views
18 Pages

21 January 2019

The effects of low molecular weight fucoidan (LMWF) in combination with high-stability fucoxanthin (HSFUCO) on cardiac function and the metabolic pathways of aging mice (Mus musculus) were investigated. We demonstrated that LMWF and HSFUCO could impr...

  • Article
  • Open Access
19 Citations
5,421 Views
12 Pages

21 January 2019

The red seaweed Pyropia yezoensis is an ideal research model for dissecting the molecular mechanisms underlying its robust acclimation to abiotic stresses in intertidal zones. Glycine betaine (GB) was an important osmolyte in maintaining osmotic bala...

  • Article
  • Open Access
24 Citations
5,775 Views
18 Pages

Venomics Reveals Venom Complexity of the Piscivorous Cone Snail, Conus tulipa

  • Mriga Dutt,
  • Sébastien Dutertre,
  • Ai-Hua Jin,
  • Vincent Lavergne,
  • Paul Francis Alewood and
  • Richard James Lewis

21 January 2019

The piscivorous cone snail Conus tulipa has evolved a net-hunting strategy, akin to the deadly Conus geographus, and is considered the second most dangerous cone snail to humans. Here, we present the first venomics study of C. tulipa venom using inte...

  • Article
  • Open Access
15 Citations
7,359 Views
15 Pages

Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore

  • Ji Fa Marshall Ong,
  • Hui Chin Goh,
  • Swee Cheng Lim,
  • Li Mei Pang,
  • Joyce Seow Fong Chin,
  • Koh Siang Tan,
  • Zhao-Xun Liang,
  • Liang Yang,
  • Evgenia Glukhov and
  • William H. Gerwick
  • + 1 author

21 January 2019

With 70% of the Earth’s surface covered in water, the marine ecosystem offers immense opportunities for drug discovery and development. Due to the decreasing rate of novel natural product discovery from terrestrial sources in recent years, many...

  • Article
  • Open Access
41 Citations
9,148 Views
25 Pages

19 January 2019

The fungi associated with marine algae are prolific sources of metabolites with high chemical diversity and bioactivity. In this study, we investigated culture-dependent fungal communities associated with the Baltic seaweed Fucus vesiculosus. Altoget...

  • Article
  • Open Access
23 Citations
5,609 Views
15 Pages

Microcarriers Based on Glycosaminoglycan-Like Marine Exopolysaccharide for TGF-β1 Long-Term Protection

  • Agata Zykwinska,
  • Mélanie Marquis,
  • Mathilde Godin,
  • Laëtitia Marchand,
  • Corinne Sinquin,
  • Catherine Garnier,
  • Camille Jonchère,
  • Claire Chédeville,
  • Catherine Le Visage and
  • Jérôme Guicheux
  • + 2 authors

19 January 2019

Articular cartilage is an avascular, non-innervated connective tissue with limited ability to regenerate. Articular degenerative processes arising from trauma, inflammation or due to aging are thus irreversible and may induce the loss of the joint fu...

  • Article
  • Open Access
16 Citations
4,947 Views
10 Pages

Activation of Human Dendritic Cells by Ascophyllan Purified from Ascophyllum nodosum

  • Wei Zhang,
  • Minseok Kwak,
  • Hae-Bin Park,
  • Takasi Okimura,
  • Tatsuya Oda,
  • Peter Chang-Whan Lee and
  • Jun-O Jin

19 January 2019

In our previous study, we showed that ascophyllan purified from Ascophyllum nodosum treatment promotes mouse dendritic cell (DC) activation in vivo, further induces an antigen-specific immune response and has anticancer effects in mice. However, the...

  • Article
  • Open Access
39 Citations
7,231 Views
11 Pages

Effect of Fermented Fish Oil on Fine Particulate Matter-Induced Skin Aging

  • Yu Jae Hyun,
  • Mei Jing Piao,
  • Kyoung Ah Kang,
  • Ao Xuan Zhen,
  • Pincha Devage Sameera Madushan Fernando,
  • Hee Kyoung Kang,
  • Yong Seok Ahn and
  • Jin Won Hyun

18 January 2019

Skin is exposed to various harmful environmental factors such as air pollution, which includes different types of particulate matter (PM). Atmospheric PM has harmful effects on humans through increasing the generation of reactive oxygen species (ROS)...

  • Article
  • Open Access
45 Citations
7,407 Views
23 Pages

In Vitro Antithrombotic Properties of Salmon (Salmo salar) Phospholipids in a Novel Food-Grade Extract

  • Alexandros Tsoupras,
  • Ronan Lordan,
  • Katie Shiels,
  • Sushanta Kumar Saha,
  • Constantina Nasopoulou and
  • Ioannis Zabetakis

18 January 2019

Marine and salmon polar lipids (PLs) extracted by conventional extractions with non-food-grade solvents (CE-salmon-PLs) possess antithrombotic bioactivities against platelet-activating factor (PAF) and thrombin. Similar effects of food-grade-extracte...

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