Table of Contents
Sensors, Volume 20, Issue 10 (May-2 2020) – 261 articles
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Cover Story (view full-size image) Diffuse optical tomography is a non-invasive photonics-based imaging technology suited to [...] Read more. Diffuse optical tomography is a non-invasive photonics-based imaging technology suited to functional brain imaging. Recent developments have proven the possibility to integrate time-resolved detectors inside the probe, in direct contact with the tissue under investigation, maximizing light harvesting and reducing system complexity. We have developed a system based on 8 probe-hosted SiPM detectors and 6 light injection fibers. Using 2 wavelengths permits quantifying both oxy- and deoxy-hemoglobin concentration evolution in the tissue. An automatic switch enables a complete tomographic acquisition to be performed in less than one second. The system was challenged against two in vivo tests: arm cuff occlusion and motor cortex brain activation. The results show that the tomographic system makes it possible to follow the evolution of brain activation over time with a 1 s resolution. View this paper.