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International Journal of Molecular Sciences, Volume 23, Issue 22

November-2 2022 - 835 articles

Cover Story: Huge amounts of toxic chemicals are discharged into aquatic systems each year, causing serious environmental problems. Advanced oxidative processes are increasingly being adopted in water remediation because reactive oxygen species, generated in situ by appropriate catalysts, efficiently decompose toxic pollutants into non-toxic CO2 and H2O. Our work demonstrated that supramolecular engineering approaches to metalloporphyrin-based nanostructures can control various structural modifications, including a large porous surface area, high thermodynamic stability, and specific morphology. Sn(IV)porphyrin-based nanostructures featuring Pd(II)-coordinated supramolecular arrays showed high photocatalytic degradation efficiency under visible-light irradiation for acid orange dye. View this paper
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Articles (835)

  • Article
  • Open Access
1 Citations
2,753 Views
16 Pages

21 November 2022

Chromatin architecture is orchestrated, and plays crucial roles during the developmental process by regulating gene expression. In embryonic stem cells (ESCs), three types of chromatin states, including active, repressive and poised states, were prev...

  • Article
  • Open Access
14 Citations
3,063 Views
23 Pages

Hispolon Cyclodextrin Complexes and Their Inclusion in Liposomes for Enhanced Delivery in Melanoma Cell Lines

  • Ishwor Poudel,
  • Manjusha Annaji,
  • Fajar Setyo Wibowo,
  • Robert D. Arnold,
  • Oladiran Fasina,
  • Brian Via,
  • Vijaya Rangari,
  • Maria Soledad Peresin,
  • Forrest Smith and
  • Muralikrishnan Dhanasekaran
  • + 2 authors

21 November 2022

Hispolon, a phenolic pigment isolated from the mushroom species Phellinus linteus, has been investigated for anti-inflammatory, antioxidant, and anticancer properties; however, low solubility and poor bioavailability have limited its potential clinic...

  • Article
  • Open Access
13 Citations
3,530 Views
12 Pages

21 November 2022

Electrochemical CO2 reduction (CO2RR) to produce high value-added chemicals or fuels is a promising technology to address the greenhouse effect and energy challenges. Formate is a desirable product of CO2RR with great economic value. Here, nitrogen-d...

  • Article
  • Open Access
10 Citations
3,392 Views
27 Pages

Genome-Scale Investigation of GARP Family Genes Reveals Their Pivotal Roles in Nutrient Stress Resistance in Allotetraploid Rapeseed

  • Ying-Peng Hua,
  • Peng-Jia Wu,
  • Tian-Yu Zhang,
  • Hai-Li Song,
  • Yi-Fan Zhang,
  • Jun-Fan Chen,
  • Cai-Peng Yue,
  • Jin-Yong Huang,
  • Tao Sun and
  • Ting Zhou

21 November 2022

The GARP genes are plant-specific transcription factors (TFs) and play key roles in regulating plant development and abiotic stress resistance. However, few systematic analyses of GARPs have been reported in allotetraploid rapeseed (Brassica napus L....

  • Article
  • Open Access
6 Citations
3,055 Views
20 Pages

New TMA (4,6,4′-Trimethyl angelicin) Analogues as Anti-Inflammatory Agents in the Treatment of Cystic Fibrosis Lung Disease

  • Chiara Tupini,
  • Adriana Chilin,
  • Alice Rossi,
  • Ida De Fino,
  • Alessandra Bragonzi,
  • Elisabetta D’Aversa,
  • Lucia Carmela Cosenza,
  • Christian Vaccarin,
  • Gianni Sacchetti and
  • Monica Borgatti
  • + 6 authors

21 November 2022

A series of new-generation TMA (4,6,4′-trimethyl angelicin) analogues was projected and synthetized in order to ameliorate anti-inflammatory activity, with reduced or absent toxicity. Since the NF-κB transcription factor (TF) plays a crit...

  • Review
  • Open Access
5 Citations
3,471 Views
29 Pages

The Four Homeostasis Knights: In Balance upon Post-Translational Modifications

  • Stefania Pieroni,
  • Marilena Castelli,
  • Danilo Piobbico,
  • Simona Ferracchiato,
  • Damiano Scopetti,
  • Nicola Di-Iacovo,
  • Maria Agnese Della-Fazia and
  • Giuseppe Servillo

21 November 2022

A cancer outcome is a multifactorial event that comes from both exogenous injuries and an endogenous predisposing background. The healthy state is guaranteed by the fine-tuning of genes controlling cell proliferation, differentiation, and development...

  • Article
  • Open Access
5 Citations
3,674 Views
19 Pages

Utility of a Molecular Signature for Predicting Recurrence and Progression in Non-Muscle-Invasive Bladder Cancer Patients: Comparison with the EORTC, CUETO and 2021 EAU Risk Groups

  • Xuan-Mei Piao,
  • Seon-Kyu Kim,
  • Young Joon Byun,
  • Chuang-Ming Zheng,
  • Ho Won Kang,
  • Won Tae Kim,
  • Yong-June Kim,
  • Sang-Cheol Lee,
  • Wun-Jae Kim and
  • Sung-Kwon Moon
  • + 2 authors

21 November 2022

To evaluate the utility of different risk assessments in non-muscle-invasive bladder cancer (NMIBC) patients, a total of 178 NMIBC patients from Chungbuk National University Hospital (CBNUH) were enrolled, and the predictive value of the molecular si...

  • Article
  • Open Access
9 Citations
3,066 Views
15 Pages

Characterization of Mitochondrial Alterations in Aicardi–Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes

  • Francesca Dragoni,
  • Jessica Garau,
  • Daisy Sproviero,
  • Simona Orcesi,
  • Costanza Varesio,
  • Silvia De Siervi,
  • Stella Gagliardi,
  • Cristina Cereda and
  • Orietta Pansarasa

21 November 2022

Aicardi–Goutières syndrome (AGS) is a rare encephalopathy characterized by neurological and immunological features. Mitochondrial dysfunctions may lead to mitochondrial DNA (mtDNA) release and consequent immune system activation. We inve...

  • Communication
  • Open Access
7 Citations
4,051 Views
15 Pages

Salivary microRNA and Metabolic Profiles in a Mouse Model of Subchronic and Mild Social Defeat Stress

  • Yuta Yoshida,
  • Yuhei Yajima,
  • Kina Kawakami,
  • Shin-ichi Nakamura,
  • Takamitsu Tsukahara,
  • Katsutaka Oishi and
  • Atsushi Toyoda

21 November 2022

Identification of early biomarkers of stress is important for preventing mood and anxiety disorders. Saliva is an easy-to-collect and non-invasive diagnostic target. The aim of this study was to characterize the changes in salivary whole microRNAs (m...

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Int. J. Mol. Sci. - ISSN 1422-0067