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Molecules, Volume 25, Issue 12

June-2 2020 - 235 articles

Cover Story: Oxime ligation represents a form of post solid-phase diversification that is highly suited to optimizing antagonists against therapeutically relevant protein–protein interactions (PPIs). Using as examples the tumor susceptibility gene 101 (Tsg101), protein tyrosine phosphatases (PTPases), and the polo-like kinase 1 (Plk1), we demonstrate how this technique provides a facile and empirical means of identifying protein–peptide interactions that may substantially increase binding affinities and selectivity. View this paper.
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Articles (235)

  • Feature Paper
  • Article
  • Open Access
17 Citations
4,456 Views
12 Pages

26 June 2020

Spider silks present extraordinary mechanical properties, which have attracted the attention of material scientists in recent decades. In particular, the strength and the toughness of these protein-based materials outperform the ones of many man-made...

  • Communication
  • Open Access
12 Citations
3,170 Views
10 Pages

26 June 2020

We use dip-pen nanolithography to accurately pattern Ni(OH)2 nanoclusters on a metachemical surface with an exceptionally large surface area. The distance between the nanoclusters can be manipulated to control the oxygen-evolution reaction current an...

  • Article
  • Open Access
6 Citations
4,960 Views
16 Pages

PbS Quantum Dots Decorating TiO2 Nanocrystals: Synthesis, Topology, and Optical Properties of the Colloidal Hybrid Architecture

  • Carlo Nazareno Dibenedetto,
  • Teresa Sibillano,
  • Rosaria Brescia,
  • Mirko Prato,
  • Leonardo Triggiani,
  • Cinzia Giannini,
  • Annamaria Panniello,
  • Michela Corricelli,
  • Roberto Comparelli and
  • Chiara Ingrosso
  • + 5 authors

26 June 2020

Fabrication of heterostructures by merging two or more materials in a single object. The domains at the nanoscale represent a viable strategy to purposely address materials’ properties for applications in several fields such as catalysis, biome...

  • Feature Paper
  • Review
  • Open Access
31 Citations
6,417 Views
22 Pages

Anion and Cation Dynamics in Polyhydroborate Salts: NMR Studies

  • Alexander V. Skripov,
  • Alexei V. Soloninin,
  • Olga A. Babanova and
  • Roman V. Skoryunov

26 June 2020

Polyhydroborate salts represent the important class of energy materials attracting significant recent attention. Some of these salts exhibit promising hydrogen storage properties and/or high ionic conductivities favorable for applications as solid el...

  • Article
  • Open Access
30 Citations
6,165 Views
16 Pages

26 June 2020

The importance of monitoring bioactive substances as food features to address sample classification and authentication is increasing. In this work, targeted liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) polyphenolic and...

  • Communication
  • Open Access
13 Citations
4,698 Views
15 Pages

26 June 2020

Viruses can be spread from one person to another; therefore, they may cause disorders in many people, sometimes leading to epidemics and even pandemics. New, previously unstudied viruses and some specific mutant or recombinant variants of known virus...

  • Article
  • Open Access
25 Citations
4,034 Views
15 Pages

Tannin-Rich Plants as Natural Manipulators of Rumen Fermentation in the Livestock Industry

  • G. M. Fagundes,
  • G. Benetel,
  • K. C. Santos,
  • K. C. Welter,
  • F. A. Melo,
  • J. P. Muir and
  • I. C. S. Bueno

26 June 2020

Condensed tannins (CTs) are plant anti-herbivore compounds with antimicrobial activity that can be used in ruminant diets as ruminal microbiome manipulators. However, not all CTs from fodder legumes are bioactive due to their wide structural diversit...

  • Communication
  • Open Access
19 Citations
5,176 Views
13 Pages

Hybrid Quinoline-Sulfonamide Complexes (M2+) Derivatives with Antimicrobial Activity

  • Dumitrela Diaconu,
  • Violeta Mangalagiu,
  • Dorina Amariucai-Mantu,
  • Vasilichia Antoci,
  • Cristian Levente Giuroiu and
  • Ionel I. Mangalagiu

26 June 2020

Two new series of hybrid quinoline-sulfonamide complexes (M2+: Zn2+, Cu2+, Co2+ and Cd2+) derivatives (QSC) were designed, synthesized and tested for their antimicrobial activity. The synthesis is straightforward and efficient, involving two steps: a...

  • Article
  • Open Access
49 Citations
9,669 Views
14 Pages

The Effect of Growth Medium Strength on Minimum Inhibitory Concentrations of Tannins and Tannin Extracts against E. coli

  • Sara Štumpf,
  • Gregor Hostnik,
  • Mateja Primožič,
  • Maja Leitgeb,
  • Juha-Pekka Salminen and
  • Urban Bren

26 June 2020

In this study the effect of growth medium strength on the minimum inhibitory concentration (MIC) of different tannins and tannin extracts against Escherichia coli was systematically investigated for the first time. Three pure compounds (vescalagin, c...

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Molecules - ISSN 1420-3049