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Molecules, Volume 19, Issue 9

September 2014 - 145 articles

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Articles (145)

  • Review
  • Open Access
45 Citations
11,596 Views
46 Pages

22 September 2014

This review deals with olefin carbonylation catalysed by Pd(II)-phosphine complexes in protic solvents. In particular, the results obtained in the carbonylation with ethene are reviewed. After a short description of the basic concepts relevant to thi...

  • Article
  • Open Access
112 Citations
13,836 Views
18 Pages

Comparative Studies on Polyphenolic Composition, Antioxidant and Antimicrobial Activities of Schisandra chinensis Leaves and Fruits

  • Andrei Mocan,
  • Gianina Crișan,
  • Laurian Vlase,
  • Ovidiu Crișan,
  • Dan Cristian Vodnar,
  • Oana Raita,
  • Ana-Maria Gheldiu,
  • Anca Toiu,
  • Radu Oprean and
  • Ioan Tilea

22 September 2014

The aim of this paper was to evaluate the antioxidant and antimicrobial activities and the polyphenolic content of Schisandra chinensis (Turcz.) Baill. leaves and fruits. The leaves are an important source of flavonoids (35.10 ± 1.23 mg RE/g plant ma...

  • Article
  • Open Access
48 Citations
8,250 Views
16 Pages

Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

  • Morgana V. De Araújo,
  • Patricia S. O. De Souza,
  • Aline C. De Queiroz,
  • Carolina B. B. Da Matta,
  • Anderson Brandão Leite,
  • Amanda Evelyn Da Silva,
  • José A. A. De França,
  • Tania M. S. Silva,
  • Celso A. Camara and
  • Magna S. Alexandre-Moreira

22 September 2014

A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions. The title compounds were evaluated for antileishmanial...

  • Article
  • Open Access
7 Citations
7,479 Views
16 Pages

Rapid Identification of Coumarins from Micromelum falcatum by UPLC-HRMS/MS and Targeted Isolation of Three New Derivatives

  • Eirini Kouloura,
  • Eirini Danika,
  • Sothea Kim,
  • Mélanie Hoerlé,
  • Muriel Cuendet,
  • Maria Halabalaki and
  • Leandros A. Skaltsounis

19 September 2014

Micromelum falcatum, a medicinal plant of the Rutaceae family, has been used in the Traditional Chinese Medicine (TCM) mainly against colds and rheumatoid arthritis. Despite its traditional use the association of its constituents with possible anti-i...

  • Review
  • Open Access
52 Citations
10,645 Views
17 Pages

New Uses for Old Drugs: The Tale of Artemisinin Derivatives in the Elimination of Schistosomiasis Japonica in China

  • Yi-Xin Liu,
  • Wei Wu,
  • Yue-Jin Liang,
  • Zu-Liang Jie,
  • Hui Wang,
  • Wei Wang and
  • Yi-Xin Huang

19 September 2014

Artemisinin (qinghaosu), extracted from the Chinese herb Artemisia annua L. in 1972, and its three major derivatives—artemether, artesunate and dihydroartemisinin—were firstly identified as antimalarials and found active against all species of the ma...

  • Review
  • Open Access
29 Citations
8,326 Views
13 Pages

19 September 2014

Titanium dioxide nanotubes (TNT) have mainly been used in dye sensitized solar cells, essentially because of a higher transport rate of electrons from the adsorbed photo-excited dye to the Ti electrode onto which TNT instead of TiO2 nanoparticles (TN...

  • Article
  • Open Access
5 Citations
6,809 Views
15 Pages

The Plant Decapeptide OSIP108 Can Alleviate Mitochondrial Dysfunction Induced by Cisplatin in Human Cells

  • Pieter Spincemaille,
  • Hamed Alborzinia,
  • Jeroen Dekervel,
  • Petra Windmolders,
  • Jos Van Pelt,
  • David Cassiman,
  • Olivier Cheneval,
  • David J. Craik,
  • Julia Schur and
  • Ingo Ott
  • + 3 authors

19 September 2014

We investigated the effect of the Arabidopsis thaliana-derived decapeptide OSIP108 on human cell tolerance to the chemotherapeutic agent cisplatin (Cp), which induces apoptosis and mitochondrial dysfunction. We found that OSIP108 increases the tolera...

  • Review
  • Open Access
29 Citations
13,350 Views
29 Pages

18 September 2014

Regular exercise contributes to healthy aging and the prevention of chronic disease. Recent research has focused on the development of molecules, such as resveratrol, that activate similar metabolic and stress response pathways as exercise training....

  • Article
  • Open Access
9 Citations
9,287 Views
13 Pages

Effect of Standardized Cranberry Extract on the Activity and Expression of Selected Biotransformation Enzymes in Rat Liver and Intestine

  • Hana Bártíková,
  • Iva Boušová,
  • Pavla Jedličková,
  • Kateřina Lněničková,
  • Lenka Skálová and
  • Barbora Szotáková

18 September 2014

The use of dietary supplements containing cranberry extract is a common way to prevent urinary tract infections. As consumption of these supplements containing a mixture of concentrated anthocyanins and proanthocyanidins has increased, interest in th...

  • Article
  • Open Access
11 Citations
9,688 Views
18 Pages

18 September 2014

We report a multi-scale simulation study of the photocycle of the rhodopsins. The quasi-atomistic representation (“united atoms” UA) of retinal is combined with a minimalist coarse grained (CG, one-bead-per amino acid) representation of the protein,...

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Molecules - ISSN 1420-3049