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Application of Immunoassays and Immunosensors for Food Safety: Recent Developments...
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Application of Immunoassays and Immunosensors for Food Safety: Recent Developments and Future Trends

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Biotechnology".

Deadline for manuscript submissions: 10 May 2026 | Viewed by 619

Special Issue Editors

Dr. Yang Lu

E-Mail Website
Guest Editor
State Key Laboratory for Food Nutrition and Safety, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China
Interests: nanoparticle; magnetic particles; microfluidic chips; MERS; fluorescence detection; deep learning
Special Issues, Collections and Topics in MDPI journals
Dr. Yinqiang Xia

E-Mail Website
Guest Editor
College of Food Science and Engineering, Northwest A&F University, Yangling 712100, China
Interests: food safety testing; biosensing; biomimetic material design
Dr. Xiaojun Bian

E-Mail Website
Guest Editor
College of Food Science & Technology, Shanghai Ocean University, Shanghai 201306, China
Interests: optical and electrochemical sensors; detection; food safety
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Immunoassays and immunosensors play critical roles in food safety and quality. These developments have allowed for the detection of food contaminants to be more efficient, less expensive, and portable. There are some promising techniques that may help to further these developments, including the use of new bioreceptors such as nanoantibodies, peptides, nanoenzymes, and microfluidic chips. In addition, deep learning has also been used to evaluate this field. These are interesting topics that we hope to discuss in this Special Issue.

This Special Issue, entitled “Application of Immunoassays and Immunosensors for Food Safety: Recent Developments and Future Trends”, aims to curate novel advances in the development and application of immunoassays and immunosensors in food safety detection. Topics of interest include, but are not limited to, the following:

  • Development of immunoassays for food safety;
  • Development of immunosensors for food safety;
  • Noval bioreceptors for fabricating immunoassays and immunosensors;
  • AI with immunoassays and immunosensors for food safety detection.

Dr. Yang Lu
Dr. Yinqiang Xia
Dr. Xiaojun Bian
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunoassays
  • immunosensors
  • food safety
  • biosensors bioreceptors
  • AI

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Published Papers (1 paper)

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Research

16 pages, 2238 KB  
Article
Highly Sensitive Lateral Flow Immunoassay for Clenbuterol and Structurally Similar Beta2-Agonists in Meat
by Elena A. Zvereva, Olga D. Hendrickson, Dmitriy V. Sotnikov, Anatoly V. Zherdev, Xinxin Xu, Chuanlai Xu and Boris B. Dzantiev
Foods 2025, 14(23), 3982; https://doi.org/10.3390/foods14233982 - 21 Nov 2025
Viewed by 361
Abstract
Beta-agonists are growth promoters sparking considerable interest in animal husbandry. However, their numerous negative effects on health have led to a number of restrictions on their presence in agricultural products, which differ depending on the type of preparation and food. In this regard, [...] Read more.
Beta-agonists are growth promoters sparking considerable interest in animal husbandry. However, their numerous negative effects on health have led to a number of restrictions on their presence in agricultural products, which differ depending on the type of preparation and food. In this regard, there is a demand for methods of their mass, rapid, and easy control with strict, focused selectivity. In this paper, a lateral flow immunoassay (LFIA) with clenbuterol (CLE), a priority β2-agonist for food safety, as the main target compound is proposed. The LFIA is based on indirect labeling of specific antibodies by gold nanoparticles via anti-species antibodies. The development of the LFIA involved optimizing the concentrations of immunoreagents and the composition of the reaction mixture (buffer type and pH, ionic strength, detergents, and additional components). In qualitative (visual) mode, the LFIA detects up to 1.0 ng/mL of CLE. In quantitative mode, the detection limit reaches 0.02 ng/mL, surpassing previously described colorimetric LFIAs. The selectivity of the obtained and used monoclonal antibodies allows for the group-specific detection of CLE and structurally close (the presence of a trimethyl residue, similar charge distribution in the benzene ring) common β2-agonists—salbutamol and mabuterol—distinguishing them from other β-agonists, including the widely used β1-agonist ractopamine, which differs in application and biological activity. The assay time is 15 min. The application of the LFIA for meat samples demonstrated that the CLE recovery ranged between 86% and 104%. The obtained results confirm the effectiveness and competitive potential of the developed assay for screening meat products outside of laboratories. Full article
(This article belongs to the Special Issue Application of Immunoassays and Immunosensors for Food Safety: Recent Developments and Future Trends)
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