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13 Results Found

  • Article
  • Open Access
9 Citations
4,757 Views
16 Pages

Torularhodin is a fungus-derived carotenoid, and the lack of downstream processing of torularhodin is still a challenge for its large-scale production. To support the industrial production of torularhodin, this work initially evaluated the efficiency...

  • Article
  • Open Access
7 Citations
2,780 Views
11 Pages

Study on the Cellular Anti-Inflammatory Effect of Torularhodin Produced by Sporidiobolus pararoseus ZQHL Isolated from Vinegar Fungus

  • Chang Liu,
  • Mei Han,
  • Fuqiang Lv,
  • Yaobin Gao,
  • Xiaoyun Wang,
  • Xujiao Zhang,
  • Yahui Guo,
  • Yuliang Cheng and
  • He Qian

2 February 2023

The red stretcher bacterium Sporidiobolus pararoseus is a high producer of carotenoids such as torularhodin, but its presence in vinegar has not been detected. Moreover, torularhodin has several biological activities, but its effect on the LPS-induce...

  • Article
  • Open Access
403 Views
21 Pages

A Novel Rhodotorula evergladensis CXCN-6 Rich in Torularhodin and PUFAs with Potent Antioxidant and Anti-Inflammatory Activities

  • Chaiwoo Park,
  • Myeongsam Park,
  • Tingting Li,
  • Chunxiao Shen,
  • Zuxuan Zheng,
  • Yitong Ge,
  • Xuanyan Jin,
  • Maolin Wei,
  • Jaehwan Choi and
  • Jae Sung Hwang
  • + 1 author

27 November 2025

Carotenoids and microbial lipids are valuable bioactive compounds with potent antioxidant and anti-inflammatory properties. Microbial biosynthesis provides a sustainable alternative to conventional plant extraction and chemical synthesis. Here, we re...

  • Article
  • Open Access
15 Citations
3,953 Views
21 Pages

27 September 2022

Torularhodin is a β-carotene-like compound from Sporidiobolus pararoseus, and its protective effect against high-fat diet (HFD)-induced hepatic dyslipidemia and inflammation was investigated. Compared to mice of C57BL/6J fed on HFD, the addition...

  • Review
  • Open Access
81 Citations
8,463 Views
19 Pages

Biotechnological Production of Carotenoids Using Low Cost-Substrates Is Influenced by Cultivation Parameters: A Review

  • Willen Silva Igreja,
  • Felipe de Andrade Maia,
  • Alessandra Santos Lopes and
  • Renan Campos Chisté

17 August 2021

Carotenoids are natural lipophilic pigments mainly found in plants, but also found in some animals and can be synthesized by fungi, some bacteria, algae, and aphids. These pigments are used in food industries as natural replacements for artificial co...

  • Feature Paper
  • Article
  • Open Access
15 Citations
3,670 Views
12 Pages

14 December 2021

In recent years, there has been an increase in the search for novel raw materials for the production of natural carotenoids. Among yeasts, Rhodotorula species have the ability to synthesize carotenoids, mainly β-carotene, torulene, and torularho...

  • Article
  • Open Access
25 Citations
4,786 Views
16 Pages

Identification, Quantification and Kinetic Study of Carotenoids and Lipids in Rhodotorula toruloides CBS 14 Cultivated on Wheat Straw Hydrolysate

  • Yashaswini Nagavara Nagaraj,
  • Viktoriia Burkina,
  • Laura Okmane,
  • Johanna Blomqvist,
  • Alexander Rapoport,
  • Mats Sandgren,
  • Jana Pickova,
  • Sabine Sampels and
  • Volkmar Passoth

Production of carotenoids and lipids by Rhodotorula toruloides CBS 14 cultivated on wheat straw hydrolysate was investigated. An ultra-high-performance liquid chromatography (UHPLC) method for carotenoid quantification was developed and validated. Sa...

  • Communication
  • Open Access
15 Citations
3,843 Views
8 Pages

In order to contribute to the elucidation of the biological role of carotenoids, the cellular response to hydrogen peroxide was analyzed in the red yeast R. mucilaginosa. For that, the wild strain C2.5t1, that produces β-carotene, torulene, and...

  • Article
  • Open Access
8 Citations
2,807 Views
16 Pages

Synergistic Effects of Stirring and Aeration Rate on Carotenoid Production in Yeast Rhodotorula toruloides CCT 7815 Envisioning Their Application as Soap Additives

  • Renata M. M. G. P. Ribeiro,
  • Bruno W. Picão,
  • Daniele O. Gonçalves,
  • Mateus Scontri,
  • Vitor T. Mazziero,
  • Cassamo U. Mussagy,
  • Vijaya Raghavan,
  • Carolina Astudillo-Castro,
  • Andrés Córdova and
  • Marcel O. Cerri
  • + 1 author

The production of carotenoids by microbial organisms has gained significant interest due to the growing demand for natural products. Among the non-model oleaginous red yeasts, Rhodotorula toruloides stands out as an appealing host for natural caroten...

  • Article
  • Open Access
2 Citations
3,415 Views
14 Pages

In this study, the wild-type Rhodotorula mucilaginosa GDMCC 2.30 and its high carotenoid-producing mutant JH-R23, which was screened from the space mutation breeding treated wild type, were used as materials. Through whole-genome sequencing and reseq...

  • Article
  • Open Access
21 Citations
6,543 Views
12 Pages

9 November 2018

Black yeasts are a highly specified group of fungi, which are characterized by a high resistance against stress factors. There are several factors enabling the cells to survive harsh environmental conditions. One aspect is the pigmentation, the melan...

  • Article
  • Open Access
20 Citations
4,911 Views
23 Pages

Bioreactor Co-Cultivation of High Lipid and Carotenoid Producing Yeast Rhodotorula kratochvilovae and Several Microalgae under Stress

  • Martin Szotkowski,
  • Jiří Holub,
  • Samuel Šimanský,
  • Klára Hubačová,
  • Pavlína Sikorová,
  • Veronika Mariničová,
  • Andrea Němcová and
  • Ivana Márová

The co-cultivation of red yeasts and microalgae works with the idea of the natural transport of gases. The microalgae produce oxygen, which stimulates yeast growth, while CO2 produced by yeast is beneficial for algae growth. Both microorganisms can t...

  • Article
  • Open Access
12 Views
24 Pages
Biology2026, 15(1), 60;https://doi.org/10.3390/biology15010060 
(registering DOI)

29 December 2025

The oleaginous yeast Rhodotorula glutinis is a promising industrial host for the simultaneous production of lipids and carotenoids, yet the transcriptional regulation governing carbon flux toward these metabolites is poorly understood. As a foundatio...