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17 Results Found

  • Article
  • Open Access
2,453 Views
11 Pages

Assessing the Impact of Simulated Color Vision Deficiency on Ophthalmologists’ Ability to Differentiate between Choroidal Melanoma and Choroidal Nevus

  • Yacoub A. Yousef,
  • Fawzieh Alkhatib,
  • Mutasem Elfalah,
  • Saif Aldeen AlRyalat,
  • Mona Mohammad,
  • Omar AlHabahbeh,
  • Reem AlJabari,
  • Sandrine Zweifel,
  • Ibrahim AlNawiaseh and
  • Robert Rejdak
  • + 1 author

20 June 2024

Background: Color vision deficiency (CVD) is an often-overlooked issue within the medical community, and its consequences remain insufficiently explored. We aim to evaluate how CVD affects diagnostic accuracy and distinguish between malignant choroid...

  • Case Report
  • Open Access
1,633 Views
8 Pages

Giant Choroidal Nevus—A Case Report

  • Nina Staneva Stoyanova,
  • Marin Atanassov,
  • Vesela Todorova Mitkova-Hristova,
  • Yordanka Basheva-Kraeva and
  • Maria Kraeva

28 March 2025

Background and Clinical Significance: Choroidal nevi are common benign growths originating from pigment cells in the fundus of the eye. They are typically up to 5 mm in diameter, asymptomatic, and incidentally discovered during routine ophthalmologic...

  • Review
  • Open Access
3 Citations
2,067 Views
19 Pages

Artificial Intelligence in Decoding Ocular Enigmas: A Literature Review of Choroidal Nevus and Choroidal Melanoma Assessment

  • Konstantina-Eleni Karamanli,
  • Eirini Maliagkani,
  • Petros Petrou,
  • Elpiniki Papageorgiou and
  • Ilias Georgalas

25 March 2025

This review examines the role of artificial intelligence (AI) in differentiating choroidal nevus (CN) from choroidal melanoma (CM), focusing on diagnosis, classification, segmentation, and prediction of malignant transformation. A literature search w...

  • Article
  • Open Access
810 Views
15 Pages

Longitudinal High-Resolution Imaging of Retinal Sequelae of a Choroidal Nevus

  • Kaitlyn A. Sapoznik,
  • Stephen A. Burns,
  • Todd D. Peabody,
  • Lucie Sawides,
  • Brittany R. Walker and
  • Thomas J. Gast

Background: Choroidal nevi are common, benign tumors. These tumors rarely cause adverse retinal sequalae, but when they do, they can lead to disruption of the outer retina and vision loss. In this paper, we used high-resolution retinal imaging modali...

  • Article
  • Open Access
8 Citations
6,099 Views
11 Pages

Assessing Choroidal Nevi, Melanomas and Indeterminate Melanocytic Lesions Using Multimodal Imaging—A Retrospective Chart Review

  • Fredy Geiger,
  • Sadiq Said,
  • Anahita Bajka,
  • Mario Damiano Toro,
  • Maximilian Robert Justus Wiest,
  • Marc Stahel,
  • Daniel Barthelmes and
  • Sandrine Anne Zweifel

11 February 2022

Using multimodal imaging, the literature proposed the following risk factors for choroidal nevus growth into melanoma: increased tumor thickness, subretinal fluid, decreased visual acuity, presence of orange pigment, ultrasound acoustic hollowness, a...

  • Review
  • Open Access
7 Citations
3,428 Views
11 Pages

Choroidal Neovascular Membranes in Retinal and Choroidal Tumors: Origins, Mechanisms, and Effects

  • Federico Di Staso,
  • Mariachiara Di Pippo and
  • Solmaz Abdolrahimzadeh

Choroidal neovascularizations are historically associated with exudative macular degeneration, nonetheless, they have been observed in nevus, melanoma, osteoma, and hemangioma involving the choroid and retina. This review aimed to elucidate the possi...

  • Article
  • Open Access
3 Citations
2,969 Views
14 Pages

Clinical and Multimodal Imaging Features of Choroidal Nevi in the Korean Population

  • Chul Hee Lee,
  • Hansang Lee,
  • Seung Min Lee,
  • Eun Young Choi,
  • Junwon Lee and
  • Min Kim

10 November 2022

Choroidal nevus is a precursor of choroidal melanoma. Multimodal imaging has become vital in predicting the malignant transformation of choroidal nevi. This single-center, retrospective study analyzed clinical characteristics and multimodal imaging f...

  • Article
  • Open Access
6 Citations
2,375 Views
11 Pages

Retromode Scanning Laser Ophthalmoscopy for Choroidal Nevi: A Preliminary Study

  • Claudia Azzolini,
  • Maura Di Nicola,
  • Francesco Pozzo Giuffrida,
  • Francesca Cappelli,
  • Claudia Bellina,
  • Francesco Viola and
  • Paolo Chelazzi

25 May 2023

The purpose of the present study was to document pathological findings on retromode imaging in choroidal nevi and evaluate its diagnostic validity, using the confocal scanning laser ophthalmoscope Nidek Mirante (cSLO). A total of 41 choroidal nevi fr...

  • Article
  • Open Access
1 Citations
1,242 Views
12 Pages

Intralesional Vessel Diameter Measured by Optical Coherence Tomography Angiography Could Improve the Differential Diagnosis of Small Melanocytic Choroidal Lesions

  • Laura Vigués-Jorba,
  • Daniel Lorenzo,
  • Cristina Pujadas,
  • Rahul Morwani,
  • Liria Yamamoto-Rodriguez,
  • Maria Baradad-Jurjo,
  • Lluis Arias,
  • Estefania Cobos,
  • Pere Garcia-Bru and
  • Juan-Francisco Santamaria
  • + 2 authors

7 June 2024

In this study, we aimed to identify the features of indeterminate choroidal melanocytic lesions visualized on optical coherence tomography angiography (OCTA) and to identify the predictors of growth. We retrospectively evaluated 86 patients with inde...

  • Article
  • Open Access
19 Citations
3,038 Views
14 Pages

Detecting Progression of Melanocytic Choroidal Tumors by Sequential Imaging: Is Ultrasonography Necessary?

  • Kelsey A. Roelofs,
  • Roderick O’Day,
  • Lamis Al Harby,
  • Gordon Hay,
  • Amit K. Arora,
  • Victoria M. L. Cohen,
  • Mandeep S. Sagoo and
  • Bertil E. Damato

10 July 2020

Purpose: To determine if ultrasonography is necessary to detect progression of choroidal melanocytic tumors undergoing sequential multi-modal imaging with color photography, autofluorescence (AF) and optical coherence tomography (OCT). Methods: All p...

  • Review
  • Open Access
8 Citations
9,261 Views
17 Pages

Fundus Autofluorescence Imaging in Patients with Choroidal Melanoma

  • Almut Bindewald-Wittich,
  • Frank G. Holz,
  • Thomas Ach,
  • Miltiadis Fiorentzis,
  • Nikolaos E. Bechrakis and
  • Gregor D. Willerding

2 April 2022

Choroidal melanocytic lesions require reliable and precise clinical examination and diagnosis to differentiate benign choroidal nevi from choroidal melanoma, as the latter may become life-threatening through metastatic disease. To come to an accurate...

  • Article
  • Open Access
6 Citations
1,936 Views
15 Pages

Quantitative Biomarkers Derived from a Novel, Contrast-Free Ultrasound, High-Definition Microvessel Imaging for Differentiating Choroidal Tumors

  • Shaheeda A. Adusei,
  • Soroosh Sabeti,
  • Nicholas B. Larson,
  • Lauren A. Dalvin,
  • Mostafa Fatemi and
  • Azra Alizad

17 January 2024

Angiogenesis has an essential role in the de novo evolution of choroidal melanoma as well as choroidal nevus transformation into melanoma. Differentiating early-stage melanoma from nevus is of high clinical importance; thus, imaging techniques that p...

  • Article
  • Open Access
5 Citations
3,959 Views
10 Pages

The Impact of Color Vision Deficiency on the Capability of Ophthalmologists to Diagnose Benign and Malignant Choroidal Tumors

  • Mutasem Elfalah,
  • Saif Aldeen AlRyalat,
  • Nakhleh E. Abu-Yaghi,
  • Mona Mohammad,
  • Ibrahim AlNawiaseh,
  • Deema Rayyan,
  • Moath Albliwi,
  • Mohammad Elfalah,
  • Fawaz AlSarairah and
  • Yacoub A. Yousef

6 April 2023

Background: Color vision deficiency (CVD) is an under-reported problem among medical personnel, and its impact is still not well characterized. We aim to assess the impact of CVD among ophthalmologists on the accuracy of diagnosing different benign a...

  • Article
  • Open Access
5 Citations
3,267 Views
15 Pages

Detecting Early Ocular Choroidal Melanoma Using Ultrasound Localization Microscopy

  • Biao Quan,
  • Xiangdong Liu,
  • Shuang Zhao,
  • Xiang Chen,
  • Xuan Zhang and
  • Zeyu Chen

Ocular choroidal melanoma (OCM) is the most common ocular primary malignant tumor in adults, and there is an increasing emphasis on its early detection and treatment worldwide. The main obstacle in early detection of OCM is its overlapping clinical f...

  • Article
  • Open Access
2 Citations
1,216 Views
11 Pages

Measurement of Melanocytic Choroidal Lesions: Ultrasound Versus Ultrawide-Field Fundus Imaging System

  • Maria C. Baradad-Jurjo,
  • Daniel Lorenzo,
  • Estel·la Rojas-Pineda,
  • Laura Vigués-Jorba,
  • Rahul Morwani,
  • Lluís Arias,
  • Pere Garcia-Bru,
  • Estefania Cobos,
  • Juan Francisco Santamaria and
  • Carmen Antia Rodríguez-Fernández
  • + 1 author

14 February 2025

Objectives: The aim of this study was to establish the concordance between conventional 20 Mhz ultrasonography and an ultrawide-field (UWF) imaging system (Optos® California) in the measurement of basal diameters of melanocytic choroidal tumors. Meth...

  • Article
  • Open Access
9 Citations
3,175 Views
17 Pages

The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition

  • Luca Hegedüs,
  • Elisabeth Livingstone,
  • Ágnes Bánkfalvi,
  • Jan Viehof,
  • Ágnes Enyedi,
  • Ágnes Bilecz,
  • Balázs Győrffy,
  • Marcell Baranyi,
  • Anna-Mária Tőkés and
  • Jeovanis Gil
  • + 9 authors

PMCA4 is a critical regulator of Ca2+ homeostasis in mammalian cells. While its biological and prognostic relevance in several cancer types has already been demonstrated, only preclinical investigations suggested a metastasis suppressor function in m...

  • Article
  • Open Access
5 Citations
3,158 Views
21 Pages

Congenital Tumors—Magnetic Resonance Imaging Findings with Focus on Rare Tumors

  • Piotr Kwasniewicz,
  • Julia Wieczorek-Pastusiak,
  • Anna Romaniuk-Doroszewska and
  • Monika Bekiesinska-Figatowska

20 December 2023

Congenital tumors are rare and, owing to this rarity, there is limited information on many of them. A total of 839 fetal and postnatal MRI studies performed in the first 3 months of life were retrospectively reviewed. They were performed with the use...