Biodegradable Polymer Platforms for Long-Acting Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 March 2026 | Viewed by 79
Special Issue Editors
Interests: biodegradable polymers; controlled delivery; nanomaterials; medical devices
Special Issues, Collections and Topics in MDPI journals
Interests: biodegradable implants; long-acting drug delivery; controlled drug delivery; multipurpose prevention technologies; parenteral formulations; personalized medicine
Special Issue Information
Dear Colleagues,
This Special Issue will highlight the latest advancements and emerging trends in biodegradable polymer platforms for long-acting drug delivery, a field that is transforming chronic disease management and patient care. Biodegradable polymer platforms offer a user-independent alternative to frequent dosing, enabling the sustained and controlled release of therapeutic agents over an extended duration, and thereby improving medication adherence and clinical outcomes. This Special Issue will explore the design, synthesis, and characterization of novel natural and synthetic biodegradable polymers and their copolymers, as well as innovative drug incorporation techniques tailored to meet patients’ specific therapeutic needs.
We invite original research, comprehensive reviews, and innovative perspectives focused on the design, synthesis, characterization, and application of natural or synthetic biodegradable polymers for long-acting drug delivery. Manuscripts may address cutting-edge formulation strategies, mechanistic studies on drug release (including diffusion, erosion, and hybrid approaches), and the influence of polymer composition and degradation kinetics on therapeutic outcomes. Submissions highlighting new manufacturing technologies for the scalable production of injectable depots, in situ forming gels, microparticles, nanoparticles, implants, and other minimally invasive delivery systems are encouraged.
Topics of interest also include combination therapies, advances in encapsulation methods, the assessment of biocompatibility and safety, regulatory considerations, and the clinical translation of these platforms. We especially welcome studies exploring personalized medicine strategies, pharmacokinetics, and real-world applications of long-acting biodegradable delivery systems. This Special Issue aims to provide a comprehensive platform for researchers and clinicians in pharmaceutics, polymer science, and biomedical engineering to share insights that will advance and inspire innovation in long-acting biodegradable drug delivery. Submissions are now open. We look forward to receiving your contributions.
Dr. Leah M. Johnson
Dr. Archana Krovi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- sustained release systems
- long-acting drug delivery
- controlled drug delivery
- biodegradable polymers
- long-acting injectables
- injectable depots
- nanoparticles and microparticles
- long-acting implants
- polymer–drug conjugates
- parenteral formulations
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