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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microfluidic Assembly of Nanocomplexes for Drug and Gene Delivery

edited by Tiago Albertini Balbino and

Ismail Eş

submission deadline 31 Dec 2025 | Viewed by 290 | Submission Open

Keywords: microfluidics; nanocomplex assembly; drug delivery; gene delivery; polymer nanoparticle; lipid nanoparticle; process optimization; mRNA vaccine delivery

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Application of PLGA Nanoparticles in Cancer Therapy

edited by

Daniele Rubert Nogueira-Librelotto

submission deadline 31 Dec 2025 | Viewed by 285 | Submission Open

Keywords: PLGA nanoparticles; cancer therapy; drug delivery; biocompatibility; controlled release; targeted therapy; theranostics; formulation strategies

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Functional Polymers for Targeted Therapeutics and Gene Delivery

edited by Łukasz Sieroń and

Emanuela Fabiola Craparo

submission deadline 31 Dec 2025 | Viewed by 272 | Submission Open

Keywords: polymer; nanoparticle; nucleic acid delivery; targeted therapy; targeted delivery; gene therapy

(This special issue belongs to the Section Gene and Cell Therapy)

Nano-Drug Delivery Systems: Tackling Cancer Metabolism and Drug Resistance

edited by

Odília Queirós

submission deadline 31 Dec 2025 | Viewed by 270 | Submission Open

Keywords: nano-drug delivery systems; tumor microenvironment; cancer metabolism; metabolic reprogramming; drug resistance; targeted therapy; combination therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances and Challenges in Nanomedicine: Translating Nanotechnology into Therapeutics for Cancer, Neurodegenerative, and Infectious Diseases

edited by

Giovanna Della Porta

and

Erwin Pavel Lamparelli

submission deadline 31 Dec 2025 | Viewed by 264 | Submission Open

Keywords: nanomedicine; targeted delivery; gene therapies; immunotherapies; cancer; infectious diseases; neurological disorders

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Multifunctional Hydrogels for Controlled Release of Bioactive Molecules

edited by

Diana C. Silva

Ana Paula Serro

and

Maria Vivero-Lopez

submission deadline 31 Dec 2025 | Viewed by 247 | Submission Open

Keywords: multifunctional hydrogels; biodegradable hydrogels; antimicrobial hydrogels; smart hydrogels; stimuli-responsive hydrogels; therapeutic hydrogels; nanogels; drug delivery; local drug delivery; controlled release; drug carriers; bioactive molecules; bioactive materials; biocompatible materials; hydrogel characterization; ex vivo and in vivo evaluation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Design of Hydrogels for Drug Delivery

edited by

Luis Morales-Quintana

and

Bustos Daniel

submission deadline 31 Dec 2025 | Viewed by 213 | Submission Open

Keywords: drug delivery; controlled release; smart hydrogels; computational modelling of hydrogels; molecular simulations of hydrogels; bioresponsive systems; hydrogel fabrication techniques

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Biopolymer Nanoparticles for Targeted Therapy in Cardiovascular Diseases

edited by Lino Sánchez-Segura and Silvio Zaina

submission deadline 31 Dec 2025 | Viewed by 190 | Submission Open

Keywords: nanoparticles; biopolymers; drug-load; drug delivery; target; cardiovascular disease; therapy

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Nanocarriers and Delivery Systems for Next-Generation Nanomedicine Therapies

edited by

Wei Huang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 173 | Submission Open

Keywords: nanocarriers; targeted delivery systems; stimuli-responsive materials; co-delivery systems; theranostic nanoplatforms; clinical translation

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Model-Informed Precision Dosing in Drug Development and Clinical Practice

edited by

Zhigang Wang

and

Bingfang Yan

submission deadline 31 Dec 2025 | Viewed by 168 | Submission Open

Keywords: model-informed precision dosing (MIPD); efficacy PKPD indexes; pharmacokinetics; pharmacodynamics; PKPD modeling and simulation; dosing algorithms; nomograms; drug development; therapeutic drug monitoring (TDM); dosing adjustments; special populations; nonlinear mixed-effects modeling (NONMEM); PK/PD models; drug– drug interactions; pediatrics; pregnancy; oral bioavailability; modelling and simulation; population pharmacokinetics

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Electrospun Fibers, Tissue Engineering, and Drug Delivery: Strategies and Potential Solutions for a Complex Issue

edited by Adrienn Kazsoki and

Constantinos Voniatis

submission deadline 31 Dec 2025 | Viewed by 166 | Submission Open

Keywords: electrospinning; fibrous mesh; drug delivery systems; biodegradable membranes; nanofibers; potential drug candidates for nanofibrous dosage forms

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Recent Advances in Drug Delivery Using AI and Machine Learning

edited by

Glen S. Kwon

Hugh D. C. Smyth

, Chinmay S. Potnis and Rebeca T. Stiepel

submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open

Keywords: nanoparticle drug delivery; artificial intelligence (AI); machine learning (ML); predictive modelling; targeted drug delivery; nanomedicine; excipient optimization; personalized drug formulations; computational drug design; AI-driven drug development

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advanced Research on Transdermal Drug Delivery

edited by

and

submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open

Keywords: transdermal drug delivery; skin drug delivery; percutaneous drug delivery; topical drug delivery; microneedles; patches; hydrogels; creams

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Development of Oncolytic Viruses as Platforms for Drug Delivery to Cancers

edited by

Alberto Reale

and

Jennifer Altomonte

submission deadline 31 Dec 2025 | Viewed by 147 | Submission Open

Keywords: oncolytic viruses; cancer; targeted drug delivery; immunotherapy; gene therapy; tumor microenvironment

(This special issue belongs to the Section Gene and Cell Therapy)

Microfluidics-Driven Formulations: Exploring Liposomes and Emulsions for Drug Delivery

edited by Naresh Yandrapalli and

Maria Camilla Bergonzi

submission deadline 31 Dec 2025 | Viewed by 130 | Submission Open

Keywords: microfluidics; drug delivery systems; liposomes; emulsions; synthetic cells; personalized medicine; multi-drug therapy; scalable manufacturing; micro-/nano-carriers; material science; pharmaceutical innovation; engineering solutions

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Innovative Therapeutic Delivery Strategies for Brain Tumors: Overcoming Barriers and Modulating the Tumor Microenvironment

edited by

and

submission deadline 31 Dec 2025 | Viewed by 117 | Submission Open

Keywords: brain tumors; drug delivery; blood– brain barrier; immunotherapy; gene therapy; tumor microenvironment; nanoparticles

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Paediatric and Neonatal Specific Dosage Forms and Administration

edited by

Smita Salunke

and Fiona O'Brien

submission deadline 31 Dec 2025 | Viewed by 110 | Submission Open

Keywords: excipients safety; non-oral drug delivery; oral drug delivery; paediatric dosage forms; neonatal dosage forms; drug administration; age-appropriate formulations

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Innovative Drug Delivery Strategies Across Biological Barriers: From Organ-on-a-Chip Models to Nanopharmaceuticals

edited by

Franciska Erdő

Amir Fahmi

and

Romána Zelkó

submission deadline 31 Dec 2025 | Viewed by 106 | Submission Open

Keywords: drug delivery systems; biological barriers; blood– brain barrier (BBB); organ-on-a-chip; lab-on-a-chip; nanopharmaceuticals; 3D printing in pharmaceutics; targeted delivery; transdermal delivery; nasal drug delivery; ocular drug delivery; pulmonary delivery; gene therapy; nanocarriers; personalized medicine; bioavailability enhancement; transporter-mediated drug delivery; in vitro models; barrier modeling; patient-centric formulations

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Overcoming Biological Barriers: Novel Strategies in Drug Delivery

edited by

Bárbara Sánchez-Dengra

and

Isabel Gonzalez-Alvarez

submission deadline 31 Dec 2025 | Viewed by 102 | Submission Open

Keywords: biological barriers; drug delivery systems; permeability

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Modern Formulation and Applications of Probiotics

edited by

Ildikó Bácskay

and Dávid Sinka

submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open

Keywords: probiotics; nanoformulation; microencapsulation; targeted delivery; next-generation probiotics; synbiotics; gut– brain axis; personalized medicine

(This special issue belongs to the Section Biologics and Biosimilars)

Innovations in Ungual and Dermal Drug Delivery Systems for Localized Therapies

edited by

Letícia Scherer Koester

and

Helder Teixeira

submission deadline 31 Dec 2025 | Viewed by 79 | Submission Open

Keywords: nano-based formulations; hydrogel-based formulations; 3D-printed formulations; films; biocompatibility; ungual; dermal; in vitro release testing (IVRT); in vitro permeation testing (IVPT)

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances and Challenges in Nasal Formulation Developments, 3rd Edition

edited by

Daisuke Inoue

submission deadline 31 Dec 2025 | Viewed by 77 | Submission Open

Keywords: nasal formulations; intranasal dissolution and permeation; mucosal absorption; excipients for nasal formulations; in vitro dissolution system; in vivo nasal dissolution and absorption

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Recent Advances in 3D Printing of Pharmaceutical Dosage Forms

edited by

Mladena Lalic-Popovic

and Veljko Krstonošić

submission deadline 31 Dec 2025 | Viewed by 77 | Submission Open

Keywords: drug delivery; 3D printing; additive manufacturing; personalized medicine; pharmaceutical excipients; polymers; biopolymers; hot melt extrusion (HME); fused deposition modeling (FDM); selective laser sintering (SLS)

(This special issue belongs to the Section Physical Pharmacy and Formulation)

The Integration of Novel Approaches in Laboratory Medicine into Precision Pharmacotherapy

edited by

Gellért Balázs Karvaly

submission deadline 31 Dec 2025 | Viewed by 75 | Submission Open

Keywords: therapeutic drug monitoring; pharmacokinetics; pharmacodynamics; bioinformatics; clinical chemistry; mass spectrometry; immunology; clinical genetics; antiinfectives; artificial intelligence

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Carbon Dot-Based Drug Delivery Systems for Targeted Therapy

edited by

Rosana Badía

and

Alfonso Fernández-González

submission deadline 31 Dec 2025 | Viewed by 68 | Submission Open

Keywords: carbon dots (CDs); drug delivery systems; targeted therapy; nanocarriers; controlled release; intracellular delivery; nanomedicine; gene delivery; fluorescent nanomaterials; bioimaging; stimuli-responsive release; smart drug carriers

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders

edited by

Ramona Meanti

and Chiara Lucchi

submission deadline 31 Dec 2025 | Viewed by 60 | Submission Open

Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection

(This special issue belongs to the Section Gene and Cell Therapy)

Natural Product Pharmaceuticals, 2nd Edition

edited by

Maria Rosaria Lauro

submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open

Keywords: pre-formulation and formulation studies; natural compounds; herbal extracts; chemical– physical and technological studies; extraction methods; stability and stabilization; in vitro and in vivo biological activities; pharmacokinetics and pharmacological studies; analytical techniques

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Micro- and Nanotechnology Empowering Combination Therapy of Cancer and Chronic Diseases

edited by

Rui Xue Zhang

submission deadline 31 Dec 2025 | Viewed by 41 | Submission Open

Keywords: nanotechnology; drug delivery; computer-aided design; nanomedicine; hydrogel; long-acting injectable; controlled drug release; combination therapy; bioavailability; biological barrier

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Innovative Approaches in Skin Formulation Development and Characterization: Scientific Foundations for Regulatory Transformation

edited by

Snezana Savic

and

Ivana Pantelić

submission deadline 31 Dec 2025 | Viewed by 35 | Submission Open

Keywords: regulatory-driven formulation development; topical products; transdermal drugs; nano/microstructured delivery systems; characterization techniques; skin models; in vitro studies; in vivo studies; in silico modeling; AI

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Innovative Nanomaterials and Metal Complexes as a Platform for Targeted Therapeutics

edited by Željko Prijović

submission deadline 31 Dec 2025 | Viewed by 30 | Submission Open

Keywords: targeted therapeutics; nanomaterials; metal complexes; drug delivery; biocompatibility; stimuli-responsive; multifunctional nanosystems; clinical translation

(This special issue belongs to the Section Drug Targeting and Design)

Inhaled Medicines: Past, Present and Future

edited by

Vivek Gupta

submission deadline 31 Dec 2025 | Viewed by 19 | Submission Open

Keywords: inhalation; nasal delivery; inhaled delivery; pulmonary; OINDP; lung diseases

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Advances in Nanoparticle-Driven Approaches for Targeted Brain Drug Delivery

edited by

Snezana Savic

and Tanja Ilić

submission deadline 31 Dec 2025 | Viewed by 17 | Submission Open

Keywords: brain-related disorders; nanotechnology; multifunctional nanoparticles; targeted drug delivery; receptor-mediated transport; carrier-mediated transport; nose-to-brain delivery; meningeal lymphatic reverse pathway; blood– brain barrier disruption

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances in Nanoparticle-Based Therapeutics: From Extracellular Vesicles to Metal Nanocarriers for Cancer Therapy

edited by Eleni K. Efthimiadou

submission deadline 31 Dec 2025 | Viewed by 15 | Submission Open

Keywords: nanoparticle; extracellular vesicle; metal-based nanotechnology; drug delivery; cancer

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advances in Drug Targeting Chemistry and Magnetic Fluid Dynamics for Enhanced Therapeutic Efficacy

edited by

Abbas Sharifi

submission deadline 1 Jan 2026 | Viewed by 24 | Submission Open

Keywords: magnetic nanoparticles; drug targeting; nanomedicine; magnetic drug delivery; surface functionalization; magnetic fluid dynamics; targeted therapy; theranostics

(This special issue belongs to the Section Drug Targeting and Design)

3D Printing—Current Pharmaceutical Applications and Future Directions

edited by Ivana M. Cotabarren,

Sanjay Garg

and Loreana C. Gallo

submission deadline 10 Jan 2026 | 4 articles | Viewed by 3988 | Submission Open

Keywords: 3D printing; pharmaceutical products; 3D printers; personalized drug delivery; additive manufacturing; new materials for 3D printing

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Smart Materials for Advanced Drug Delivery Systems and Pharmaceutical Applications

edited by

Milena A. Vega

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1594 | Submission Open

Keywords: smart materials; drug delivery systems; pharmaceutical applications; responsive materials; hydrogels; functionalized nanoparticles; targeted drug release; biological stimuli

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Ocular Drug Delivery System

edited by

Xin Fan

and

Elena Sánchez-López

submission deadline 20 Jan 2026 | Viewed by 106 | Submission Open

Keywords: drug delivery; nanoparticles; controlled release; hydrogels; liposomes; microneedle arrays

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Pharmacokinetics of Targeted Anti-Cancer Drugs

edited by

Marios Spanakis

and Retheesh S. Thankan

submission deadline 20 Jan 2026 | Viewed by 78 | Submission Open

Keywords: pharmacokinetics; targeted anti-cancer drugs; in vivo models of PK studies; personalized medicine; drug design

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Magnetic Materials for Biomedical Applications

edited by

Carlos O. Amorim

submission deadline 20 Jan 2026 | Viewed by 76 | Submission Open

Keywords: magnetic materials; magnetic nanoparticles; nanomedicine; nanotechnology; theranostics; drug delivery systems; magnetic gels; magnetic hyperthermia; magnetic imaging

(This special issue belongs to the Section Drug Delivery and Controlled Release)

3D Bioprinting: Current Advances and Future Directions in Drug Delivery

edited by

Hyun-Ouk Kim

and

Hyungseok Lee

submission deadline 20 Jan 2026 | Viewed by 75 | Submission Open

Keywords: 3D bioprinting; drug delivery; bioink development; tissue engineering; controlled release systems

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Biocompatible Liposomes for Drug Delivery

edited by

Katona Gábor

and Anita Bogdanov

submission deadline 20 Jan 2026 | Viewed by 69 | Submission Open

Keywords: liposome; biocompatible liposomes; drug delivery system; anti-cancer therapy; anti-inflammatory therapy; antibiotics

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Novel Technologies and Challenges for the Delivery of Biomacromolecular Drugs

edited by

Wenhao Wang

Junhuang Jiang

and

Zhengwei Huang

submission deadline 20 Jan 2026 | Viewed by 54 | Submission Open

Keywords: drug delivery; biomacromolecular drug; drug stability; controlled release

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Nanoparticles for Glioblastoma Therapy

edited by Shambhavi Pandey and

Benjamí Oller-Salvia

submission deadline 20 Jan 2026 | Viewed by 46 | Submission Open

Keywords: nanoparticles; blood– brain barrier; gene delivery; glioblastoma; cancer stem cells; biomaterials

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Microbial Infections and Wound Healing: Medicinal-Chemistry and Technological Based Approaches, 2nd Edition

edited by

Ivana Cacciatore

and

Lisa Marinelli

submission deadline 20 Jan 2026 | Viewed by 38 | Submission Open

Keywords: antimicrobial agents; small molecule therapeutics; drug repurposing; antimicrobial peptides (AMPs); drug delivery systems; nanotechnology; wound dressings; polymers; smart biomaterials; 3D bioprinting; electrospun fibers; biotechnology; bioengineering

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Multifunctional Nanoparticles: Diagnostics, Therapy, and Beyond

edited by

Karla Santacruz-Gomez

and Seong Hoon Jeong

submission deadline 20 Jan 2026 | Viewed by 37 | Submission Open

Keywords: multifunctional nanoparticles; theranostic nanoplatforms; stimuli-responsive drug delivery; nanoparticle-based biomedical imaging; early disease detection with nanotechnology; real-time biomarker monitoring

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advanced Nanoencapsulation Platforms for Bioactive Compounds and Drugs in Pain Therapy

edited by

Lígia N.M. Ribeiro

submission deadline 20 Jan 2026 | Viewed by 29 | Submission Open

Keywords: nanoencapsulation; pain therapy; bioactive compounds; drug delivery; nanoformulations; sustained release; chronic pain; neuropathic pain; nanomedicine; targeted delivery

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Prodrug Strategies for Enhancing Drug Stability and Pharmacokinetics

edited by

Federico Zappaterra

and

Pier Paolo Giovannini

submission deadline 30 Jan 2026 | Viewed by 451 | Submission Open

Keywords: prodrug development; drug solubility enhancement; pharmacokinetic optimization; bioavailability improvement; innovative drug design; green biocatalytic approaches

(This special issue belongs to the Section Drug Targeting and Design)

Advances in Dendritic Cell-Based Delivery Systems

edited by Jacqueline Oliva-Ramírez and

Christian Lehmann

submission deadline 30 Jan 2026 | Viewed by 173 | Submission Open

Keywords: dendritic cells; cancer immunotherapy; targeted therapy; personalized medicine; tumor microenvironment; vaccine formulations; combination therapies; metabolic reprogramming

(This special issue belongs to the Section Drug Targeting and Design)

GLP-1 Receptor Agonists: Current Understanding and Emerging Therapeutic Horizons

edited by

Maria Bogdan

submission deadline 30 Jan 2026 | Viewed by 53 | Submission Open

Keywords: GLP-1 receptor agonists; nanotechnology; pharmacokinetics; delivery systems; advanced therapies; adherence; drug repurposing

(This special issue belongs to the Section Clinical Pharmaceutics)

Cyclodextrins and Their Pharmaceutical Applications

edited by

Thorsteinn Loftsson

and Renata Maria Văruț

submission deadline 31 Jan 2026 | 7 articles | Viewed by 12087 | Submission Open

Keywords: cyclodextrin complexes; drug delivery systems; pharmaceutical applications; solubility enhancement; therapeutic efficacy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Displaying special issue 301-350 on page 7 of 10.

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