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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into the Pathogenesis, Immunology and Treatment of Human Babesiosis and Other Erythrocytic Pathogens

edited by

Luis A. Marcos

and

Dana G. Mordue

submission deadline 20 Jun 2025 | 4 articles | Viewed by 6139 | Submission Open

Keywords: piroplasms; Babesia species; erythrocytic pathogens; human babesiosis; host response; diagnosis; epidemiology; management

(This special issue belongs to the Section Parasitic Pathogens)

New Insights into Viral Pathogenesis, Host Immune Responses and Immunotherapies

edited by

Dawei Zhou

, Taiwei Li and

Theresa Chang

submission deadline 20 Jun 2025 | 2 articles | Viewed by 5020 | Submission Open

Keywords: virus-host interaction; viral replication; viral pathogenesis; host immune responses; antiviral immunotherapies

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

New Insights into Rickettsia and Related Organisms

edited by

Alison Luce-Fedrow

and Kristin E. Mullins

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3577 | Submission Open

Keywords: Rickettsia; Orientia; Ehrlichia; Anaplasma; Coxiella; Borrelia; Bartonella; Babesia

(This special issue belongs to the Section Bacterial Pathogens)

The Remaining Threat of Magnaporthe oryzae

edited by Martha C. Giraldo

submission deadline 20 Jun 2025 | 1 articles | Viewed by 3351 | Submission Open

Keywords: Magnaporthe oryzae; molecular mechanisms; signaling pathway; plant-pathogen interactions; blast; rice blast; pathogenecity

(This special issue belongs to the Section Fungal Pathogens)

Updates on Animal Papillomaviruses

edited by

Francesca De Falco

and Franco Roperto

submission deadline 20 Jun 2025 | 2 articles | Viewed by 3075 | Submission Open

Keywords: papillomavirus; trans-species transmission; environmental contamination

(This special issue belongs to the Section Viral Pathogens)

Recent Advances in Taeniasis and Cysticercosis

edited by

Hector H. Garcia

, Christina M. Coyle, Gagandeep Singh and

Oscar H. Del Brutto

submission deadline 30 Jun 2025 | 10 articles | Viewed by 32522 | Submission Open

Keywords: Taenia solium; taeniasis; cysticercosis; neurocysticercosis; epilepsy; nervous system; central nervous system; diagnostics

(This special issue belongs to the Section Parasitic Pathogens)

Role of Microorganisms in Breast Cancer

edited by

María Leonor Fernández-Murga

and

Antonio Llombart-Cussac

submission deadline 30 Jun 2025 | 9 articles | Viewed by 31611 | Submission Open

Keywords: Microorganism; Pathogens; Microbiota and dysbiosis; Antibiotics; Estrobolome; Probiotics; Multidrug resistance and microbiota; Breast milk bacteriome; Cathelicidin antimicrobial protein in breast cancer; Inflammation and dysbiosis and breast cancer

Arthropod-Borne Flavivirus Infections: One-Health Approaches in Epidemiology, Pathogenesis, Diagnosis, Prevention, and Treatment

edited by

Irena Tabain

and

Vladimir Savic

submission deadline 30 Jun 2025 | 6 articles | Viewed by 14415 | Submission Open

Keywords: flavivirus; epidemiology; arboviruses; one health; arthropod vector

(This special issue belongs to the Section Viral Pathogens)

An Update on Fungal Infections

edited by

María del Rocío Reyes Montes

and

Esperanza Duarte-Escalante

submission deadline 30 Jun 2025 | 7 articles | Viewed by 14243 | Submission Open

Keywords: fungal infections; host– parasite interaction; pathogenesis; epidemiology; climate change; diagnosis; treatment

(This special issue belongs to the Section Fungal Pathogens)

Oncolytic Mechanisms of Viruses: Effect on Tumor Cells and Role of the Tumor Microenvironment

edited by

and

submission deadline 30 Jun 2025 | 5 articles | Viewed by 13461 | Submission Open

Keywords: Viral oncolysis; Oncolytic Viruses (OVs); Mesenchymal to Epithelial Transition (MET); Tumor virotherapy; Immune system; Tumor microenvironment (TME)

(This special issue belongs to the Section Viral Pathogens)

Pathogenesis Mechanisms and Antimicrobial Strategies against Multidrug-Resistant Pathogens

edited by

Nikolaos Spernovasilis

and

Constantinos Tsioutis

submission deadline 30 Jun 2025 | 5 articles | Viewed by 11588 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial treatment; bacteriophages; drug development; efflux; enzymes; immunology; infection control; monoclonal antibodies; multi-drug resistance; nanoparticles; pathogenesis; pathophysiology; target

(This special issue belongs to the Section Bacterial Pathogens)

Leishmaniasis: Current Status and Future Perspectives

edited by

Maria do Socorro Pires Cruz

and

Flávia de Oliveira Cardoso

submission deadline 30 Jun 2025 | 1 articles | Viewed by 4964 | Submission Open

Keywords: leishmaniasis; control; therapy; epidemiology; vector; genetics; immunotherapy; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Multidrug-Resistant Bacteria in Wildlife: A “One Health” Approach to Surveillance, Transmission and Control

edited by

María Teresa Tejedor-Junco

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4159 | Submission Open

Keywords: multidrug resistance; wildlife; “ One Health”

(This special issue belongs to the Section Bacterial Pathogens)

Salmonella: A Global Health Threat and Food Safety Challenge

edited by

Chyer Kim

and

Yangjin Jung

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2839 | Submission Open

Keywords: salmonellosis; virulence; surveillance; climate change; and prevention

(This special issue belongs to the Section Bacterial Pathogens)

Emergence and Re-Emergence of Animal Viral Diseases

edited by

Zaheer Ahmed

submission deadline 30 Jun 2025 | 3 articles | Viewed by 2762 | Submission Open

Keywords: animal viral diseases; virus emergence; molecular characterization; novel assays; whole-genome sequencing (WGS); foreign animal diseases; disease surveillance and monitoring; pathogen evolution; diagnostic innovations; epidemiological trends

(This special issue belongs to the Section Emerging Pathogens)

Rare Fungal Infection Studies

edited by

Rebecca A. Drummond

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2584 | Submission Open

Keywords: rare; fungal infections; fungal pathogenesis; anti-fungal therapies; fungal case study; hospital report

(This special issue belongs to the Section Fungal Pathogens)

Molecular Biology of Papillomaviruses

edited by

Thomas Melendy

and Kavi Mehta

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2160 | Submission Open

Keywords: HPV; papillomavirus; viral replication; viral transcription; episomal maintenance; DNA damage response; viral amplification; differentiation-dependent amplification; viral life cycle; HPV host– pathogen interactions; genetic instability; genome maintenance

(This special issue belongs to the Section Viral Pathogens)

Fungal Pathogenicity Factors: 2nd Edition

edited by

Xin Guan

and Xiaoli Chang

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1721 | Submission Open

Keywords: pathogenicity factor; effectors; mycotoxins; pathogenesis; fungicides; plant; innate immunity; vascular bundle; stress responses; plant– pathogen interaction

(This special issue belongs to the Section Fungal Pathogens)

Current Research on Bacillus anthracis Infection

edited by Viviana Manzulli and

Domenico Galante

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1427 | Submission Open

Keywords: Bacillus anthracis; epidemiology; pathogenesis; diagnostics; genomics

(This special issue belongs to the Section Bacterial Pathogens)

Thinking Out-of-the-Box: Innovative Approaches for the Treatment of Biofilm-Related Infections

edited by

Débora C. Coraça-Huber

and

Christopher Spiegel

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1282 | Submission Open

Keywords: biofilm; immune system; implant; PJI; holistic approach; antibiotic-boosting activity

(This special issue belongs to the Section Bacterial Pathogens)

Sepsis and Group A Streptococcus

edited by Vaclava Adamkova and

Helena Brodská

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1062 | Submission Open

Keywords: streptococcus pyogenes; invasive infections; bacteriaemia; sepsis; biomarkers; antimicrobial resistance; pathogenesis; virulence factors

(This special issue belongs to the Section Bacterial Pathogens)

HTLV: Celebrating the 45th Anniversary Since Its Discovery

edited by

Eduardo Gotuzzo

submission deadline 30 Jun 2025 | Viewed by 1057 | Submission Open

Keywords: HTLV; retrovirus; oncogenic; malignancy

(This special issue belongs to the Section Viral Pathogens)

Zoonotic Streptococci

edited by

Zongfu Wu

submission deadline 30 Jun 2025 | 1 articles | Viewed by 953 | Submission Open

Keywords: zoonotic streptococci; pathogenesis; antibiotic resistance; vaccine; diagnosis; epidemiology

(This special issue belongs to the Section Bacterial Pathogens)

Biomarkers for Early Detection of Viral Infections: Current Status and Challenges

edited by

Danijela Miljanovic

Ana Banko

and

Ivana Lazarevic

submission deadline 30 Jun 2025 | Viewed by 413 | Submission Open

Keywords: viral detection; biomarkers; nucleic acid (DNA; RNA); viral proteins; antibodies; host response; NGS; omics approach

(This special issue belongs to the Section Viral Pathogens)

New Insights on Parasites as Bioindicators

edited by Jaqueline Bianque de Oliveira and Müller Ribeiro Andrade

submission deadline 30 Jun 2025 | Viewed by 327 | Submission Open

Keywords: parasitic ecology; habitat change; bioindicators; emerging infectious diseases; zoonoses; wildlife; One Health

(This special issue belongs to the Section Parasitic Pathogens)

Periodontal Pathogens—Virulence, Infection, and Host Response

edited by Kiyoshi Nishikawa and Yoshiaki Hasegawa

submission deadline 30 Jun 2025 | Viewed by 268 | Submission Open

Keywords: periodontitis; pathogen; virulence; host response; dysbiosis

Viruses and Bacteria from Wastewater submission deadline 30 Jun 2025 | Viewed by 242 | Submission Open

Keywords: anti-microbial resistance; wastewater epidemiology; parasites; viruses; bacteria

Neuroinfectious Diseases

edited by Kiran Thakur and Christina M. Coyle

submission deadline 30 Jun 2025 | Viewed by 192 | Submission Open

Keywords: neurotropic infections; viral encephalitis; bacterial meningitis; tropical neurological infections

Viral Hepatitis Among Specific Populations: Epidemiology, Transmission, Treatment, and Prevention

edited by

Aldemir B. Oliveira-Filho

submission deadline 30 Jun 2025 | Viewed by 185 | Submission Open

Keywords: epidemiology; diagnosis; prevention; control; access and care strategies

(This special issue belongs to the Section Viral Pathogens)

Candida albicans Virulence and Therapeutic Strategies

edited by

Maria Elisa Rodrigues

and Liliana Fernandes

submission deadline 30 Jun 2025 | Viewed by 166 | Submission Open

Keywords: Candida albicans; virulence factors; biofilm; antimicrobial resistance; therapeutic strategies; host interactions

(This special issue belongs to the Section Fungal Pathogens)

Epigenetic Regulation During Viral Infections and Latency

edited by

Prasun K. Datta

and

Manish K. Gupta

submission deadline 30 Jun 2025 | Viewed by 137 | Submission Open

Keywords: epigenetics; viral infections; DNA methylation; histone modification; cross-talk between metabolism and epigenetics; novel therapeutics

(This special issue belongs to the Section Viral Pathogens)

Rat Lungworm Disease—Second Edition

edited by

Susan Jarvi

submission deadline 30 Jun 2025 | Viewed by 116 | Submission Open

Keywords: Angiostrongylus cantonensis; rat lungworm; neuroangiostrongyliasis; accidental hosts; parasitic nematode

Oral Microbiome and Human Systemic Health

edited by

Milena Radunovic

and

Natalia Di Pietro

submission deadline 13 Jul 2025 | 12 articles | Viewed by 28135 | Submission Open

Keywords: oral microbiome; systemic health; microorganisms; chronic diseases; immune responses

Understanding Microbial Keratitis: Basic Science, Epidemiology, Diagnosis and Management

edited by

Chameen Samarawickrama

, Vannessa Leung, Yashar Seyed Razavi and Samantha Bobba

submission deadline 13 Jul 2025 | 1 articles | Viewed by 1626 | Submission Open

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Detection of Indoor Fungi: Part II

edited by

Donát Magyar

submission deadline 15 Jul 2025 | 5 articles | Viewed by 10225 | Submission Open

Keywords: molds; fungi; indoor environment; indoor air quality and molds; mycotoxins; fungal MVOCs; fungal allergens; pathogenic fungi in the indoor environment; biodeterioration by fungi in the indoor environment; aeromycology; fungal diversity

(This special issue belongs to the Section Fungal Pathogens)

Exploring the Epidemiology, Pathogenicity, and Therapeutic Options of Staphylococcus spp.: 2nd Edition

edited by

Francesca Paola Nocera

and

Patrizia Nebbia

submission deadline 15 Jul 2025 | 3 articles | Viewed by 4627 | Submission Open

Keywords: Staphylococcus spp.; transmission; pathogenesis of infections; antibiotic resistance; methicillin resistance; therapy; zoonotic diseases; One Health

(This special issue belongs to the Section Bacterial Pathogens)

Leveraging Technological Advancement for Pandemic Preparedness

edited by Kai Sen Tan,

Chee Keng MOK

Yaw Shin Ooi

, Chee Wah Tan,

Mookkan Prabakaran

, Dahai Luo and Poying Chia

submission deadline 15 Jul 2025 | Viewed by 1046 | Submission Open

Keywords: pandemic preparedness; disease X; technological platforms; treatment and prevention; viral infectious diseases

(This special issue belongs to the Section Viral Pathogens)

Acanthamoeba Infections

edited by Rubén L. Rodríguez-Expósito and

Ines Sifaoui

submission deadline 15 Jul 2025 | 1 articles | Viewed by 987 | Submission Open

Keywords: Acanthamoeba ; mechanism of action; programmed cell death; in vivo research on Acanthamoeba infections; chemotherapy advances

(This special issue belongs to the Section Parasitic Pathogens)

The Host-Pathogen Interaction in Cystic Fibrosis

edited by

Angela Sandri

, Caterina Signoretto and

Laura Veschetti

submission deadline 15 Jul 2025 | Viewed by 352 | Submission Open

Keywords: cystic fibrosis; respiratory infection; host– pathogen interaction; CFTR; immune system

Molecular and Cellular Research on Targets for Antimalarial Therapy Development

edited by Sanjay Arvind Desai

submission deadline 15 Jul 2025 | Viewed by 273 | Submission Open

Keywords: malaria; molecular biology; cellular biology; antimalarial drug discovery and development; malaria vaccines

(This special issue belongs to the Section Parasitic Pathogens)

Advances in Chlamydia-Related Diseases

edited by

Katalin Burián

submission deadline 15 Jul 2025 | Viewed by 133 | Submission Open

Keywords: chlamydia; pathomechanism; host interaction; host-specific immunity; in vitro persistence model; epidemiology; treatment; vaccination

Parasites: Epidemiology, Treatment and Control: 2nd Edition

edited by

Ali Raza

and

Andrew Richard Williams

submission deadline 20 Jul 2025 | 5 articles | Viewed by 9326 | Submission Open

Keywords: endoparasites; ectoparasites; zoonoses; epidemiology; treatment; control

(This special issue belongs to the Section Parasitic Pathogens)

Emerging and Re-Emerging Bacterial Infections

edited by

William S. Lawrence

submission deadline 20 Jul 2025 | 3 articles | Viewed by 6571 | Submission Open

Keywords: bacteria; human infection; emerging infections; pathogenesis; mutation; virulence; animal model of infection; antibiotic-resistance; immunity; therapeutics

(This special issue belongs to the Section Emerging Pathogens)

Staphylococcus aureus: From Immunity to Vaccine Development

edited by Irshad Ahmed Hajam and April Aralar

submission deadline 20 Jul 2025 | Viewed by 306 | Submission Open

Keywords: S. aureus; host biology; pathobiont interactions; clinical research

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

HIV/AIDS: Epidemiology, Drug Resistance, Treatment and Prevention

edited by Marta Pingarilho, Mafalda N. S. Miranda and

Ana Barroso Abecasis

submission deadline 31 Jul 2025 | 5 articles | Viewed by 9687 | Submission Open

Keywords: epidemiology of HIV; HIV drug resistance; HIV transmission; HIV treatment; HIV prevention

(This special issue belongs to the Section Emerging Pathogens)

Hand–Foot–Mouth Disease

edited by

Kow-Tong Chen

submission deadline 31 Jul 2025 | 2 articles | Viewed by 3643 | Submission Open

Keywords: hand– foot– mouth disease; Coxsackie virus; epidemiology; pathogenesis; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Remaining Challenges of HBV Infection: Pathogenesis, Immune Response, Diagnosis and Therapeutic Strategies

edited by

Ivana Lazarevic

submission deadline 31 Jul 2025 | 3 articles | Viewed by 3326 | Submission Open

Keywords: HBV; pathogenesis; immune response; clinical management; diagnostic methods; new biomarkers; antiviral therapy; new antiviral strategies; vaccines and prevention

(This special issue belongs to the Section Viral Pathogens)

Exploring Natural Products as Antiparasitic Agents: Efficacy Against Parasites of Veterinary and Public Health Significance

edited by

Agustín Olmedo-Juárez

and

Elke Von Son-De Fernex

submission deadline 31 Jul 2025 | 2 articles | Viewed by 3054 | Submission Open

Keywords: plant extracts; phytochemicals; fungi; parasites; anthelmintics; secondary metabolites; natural compounds; ethnoveterinary

(This special issue belongs to the Section Parasitic Pathogens)

Host-Pathogen Interactions During Pathogenic Human Coronavirus Infection: 2nd Edition

edited by

Masfique Mehedi

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2330 | Submission Open

Keywords: COVID-19; spike; mRNA; goblet cell; viremia; pneumonia; convalescent; antibody; transmission

(This special issue belongs to the Section Viral Pathogens)

Focus on Cervicovaginal Health: Microbiome, Sexually Transmitted Infections, and Beneficial Microbes: 2nd Edition

edited by

Antonella Marangoni

and

Claudio Foschi

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2086 | Submission Open

Keywords: vaginal microbiome; vaginal metabolome; lactobacilli; host– pathogen interactions; sexually transmitted infections; Chlamydia; gonorrhea; vaginal dysbiosis; vulvovaginal candidiasis; animal models

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

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