Emerging and Rare Fungal Pathogens in a Changing World

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 10 July 2026 | Viewed by 419

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Guest Editor
Dipartimento di Scienze di Laboratorio ed Ematologiche, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
Interests: medical mycology; antifungal resistance; fungal typing; MALDI-TOF MS; FTIR
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Special Issue Information

Dear Colleagues,

Over the past two decades, the frequency and diversity of invasive fungal infections have risen markedly, reflecting profound changes in global health and patient demographics. The growing population of individuals with compromised immunity, including recipients of solid-organ or bone marrow transplants, patients undergoing major surgery, and those affected by AIDS, malignancies, or immunosuppressive therapies, has provided fertile ground for opportunistic fungal pathogens. An expanding spectrum of emerging and rare yeasts and molds is changing the landscape of fungal infections. Many of these organisms exhibit intrinsic resistance to standard antifungal therapies, complicating clinical management and emphasizing the need for accurate identification and tailored treatment and surveillance strategies. This Special Issue will explore the most innovative aspects of diagnostics, epidemiology, molecular mechanisms, and therapeutics surrounding emerging or rare fungal pathogens.

In an era of increasing medical complexity and global environmental change, it is my honor to warmly invite colleagues in the scientific community to submit original articles, reviews, and clinical cases related to emerging or rare fungal infections in humans.

Dr. Elena De Carolis
Guest Editor

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Keywords

  • emerging fungal pathogens
  • antifungal resistance
  • advances in fungal diagnosis

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Published Papers (1 paper)

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Research

23 pages, 2065 KB  
Article
Seasonal Turnover in Bat Skin Mycobiota: Contrasting Fungal Communities Between Hibernation and Reproduction in Greater Mouse-Eared Bats (Myotis myotis)
by Rafał Ogórek, Jakub Suchodolski, Justyna Borzęcka and Tomasz Kokurewicz
Pathogens 2026, 15(1), 83; https://doi.org/10.3390/pathogens15010083 - 12 Jan 2026
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Abstract
The skin of bats hosts diverse microbial communities, yet most research has focused on bacteria or single fungal pathogens such as Pseudogymnoascus destructans. Here, we present the first direct comparison of culturable skin mycobiota in the greater mouse-eared bat (Myotis myotis [...] Read more.
The skin of bats hosts diverse microbial communities, yet most research has focused on bacteria or single fungal pathogens such as Pseudogymnoascus destructans. Here, we present the first direct comparison of culturable skin mycobiota in the greater mouse-eared bat (Myotis myotis) between hibernation and the reproductive season. Swabs collected from hibernating bats in the Nietoperek reserve and from maternity colonies in Lipy yielded 41 fungal species, including 27 that represent new records for M. myotis. Winter assemblages were less diverse but strongly dominated by Penicillium (>90% of isolates), while summer maternity roosts supported broader communities shaped by environmental exposure and plant-associated fungi. Despite seasonal turnover, a small set of taxa, including Aspergillus fumigatus, Mucor fragilis, and Pseudogymnoascus pannorum, persisted across both seasons, indicating the presence of a limited core mycobiota. Richness was higher on wing membranes than on tail membranes, whereas biometric variables such as sex, age, body mass, and forearm length showed only weak and inconsistent associations with fungal diversity. These findings demonstrate that seasonal filtering is likely one of the main factors determining the skin mycobiota in M. myotis. Additionally, we expand the known fungal diversity of this species, and emphasize its role as a reservoir of environmental, opportunistic, and pathogenic fungi. Full article
(This article belongs to the Special Issue Emerging and Rare Fungal Pathogens in a Changing World)
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