Genes, Lifestyle and Non-communicable Diseases

Dear Colleagues,

The completion of human genome sequencing and the introduction of high-throughout ‘omic’ technologies have allowed a better understanding of lifestyle–gene interactions, which vary between genotypes, with the ultimate goal of developing personalised nutrition strategies for optimal health and disease prevention.

Humans are affected by both lifestyle and genetic factors; both factors must be considered equally to maintain the normal health condition of an individual. Previous studies were mostly directed at either the effects of lifestyle factors alone or solely genes; none have focused on both together. Recently, gene–nutrient and gene–physical activity interactions have been investigated. Nutrition and physical activity may impact health outcomes by directly affecting gene expression in critical metabolic pathways. Improved health outcomes can be achieved if nutritional requirements are individually tailored, taking into consideration the genetic make-up, life stage, dietary preferences, physical activity levels, and health status of an individual. This area of scientific research necessitates a better understanding of the mechanisms of nutrient-dependent interactions at the genetic, molecular, protein, and metabolic profile levels.

This Special Issue, “Genes, Lifestyle and Non-Communicable Diseases”, welcomes manuscripts detailing human and animal studies focused on the roles of lifestyle (diet and physical activity) and genetic factors in non-communicable diseases, such as cardiovascular disease, diabetes, and obesity, as well as in vitro studies aimed at elucidating the potential molecular mechanisms of genetic associations and lifestyle–gene interactions. Experimental papers, up-to-date review articles, and commentaries will all be considered.

Prof. Dr. Karani S. S Vimaleswaran
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.