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Innovations in Neonatal and Early Childhood Nutrition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".

Deadline for manuscript submissions: 15 December 2026 | Viewed by 3068

Editors


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Guest Editor
Health Sciences Department, Ursinus College, Collegeville, PA 19426, USA
Interests: nutrition; diet quality; diet patterns

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Guest Editor Assistant
Nationwide Children’s Hospital, Columbus, OH 43205, USA
Interests: nutrition; pancreas; gastroenterology; body composition; growth

Special Issue Information

Dear Colleagues,

It is clear that adequate nutrition in the first 1000 days of life provides the foundation for lifelong health. It represents a critical time and window of opportunity to build a child’s future. This Special Issue focuses on the period after birth through early childhood. One of the areas in neonatal nutrition that requires additional data is supplementation, particularly in preterm infants. There is substantial evidence for the benefits of breastfeeding, but understanding breastfeeding practices and access to breastfeeding are needed to support breastfeeding persons. How children are fed may be as important as what they are fed; therefore, the relationships between feeding practices and outcomes related to eating behavior and dietary intake are of interest. Other topics of interest include the following: complementary foods, diet patterns, parental nutrition perceptions, early life nutrition in specific disease states, and external factors influencing diet patterns among young children (e.g., nutrition children (e.g., nutrition security). Nutrition researchers, especially dietitians, pediatricians, neonatologists, and psychologists, are invited to submit original research articles, reviews, and commentaries that provide insight into novel and understudied aspects of nutrition from infancy through early childhood.

Dr. Alyssa Tindall
Guest Editor

Dr. Rosara Bass
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neonatal nutrition
  • neonatal growth
  • childhood nutrition
  • child dietary patterns
  • child diet quality

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Published Papers (2 papers)

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13 pages, 1965 KB  
Article
Nutritional Management for Infants with Cystic Fibrosis Born with Meconium Ileus: A 15-Year Review
by Susan Gemma, Anne Rice, Rosara Bass, Mariah Eisner and Katelyn Krivchenia
Nutrients 2026, 18(15), 2463; https://doi.org/10.3390/nu18152463 - 28 Jul 2026
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Abstract
Background/Objectives: Meconium ileus (MI) related to cystic fibrosis (CF) presents unique nutrition challenges for newborns. The aim of this study was to present a descriptive case series reviewing the management practice and clinical outcomes of infants with CF and MI at a [...] Read more.
Background/Objectives: Meconium ileus (MI) related to cystic fibrosis (CF) presents unique nutrition challenges for newborns. The aim of this study was to present a descriptive case series reviewing the management practice and clinical outcomes of infants with CF and MI at a large, quaternary care center. Methods: A retrospective analysis examined patients born with CF and MI over fifteen years at a large pediatric hospital in the Midwest. Patient demographics, prenatal imaging data, newborn screening results, stool studies, sweat chloride and details of the clinical course were obtained through the electronic medical record (EMR). Outcomes including length of stay (LOS), timing of surgery, and duration of total parenteral nutrition (TPN) needs were compared between infants with and without a surgical ostomy. Associations of MI severity with CF genotype, stool elastase, and prenatal imaging findings were evaluated. Results: A total of 30 neonates (21 female, 9 male) were included. Surgery was required in 26 infants, with 18 requiring ostomy placement. There were no significant correlations between CF genotype, stool elastase, or prenatal imaging findings with need for ostomy placement. Compared to those without ostomy placed, infants with ostomies had significantly longer median [IQR] LOS (71 [61, 105] vs. 22 [16, 32] days; difference 49, 95% CI 34–77) and duration of TPN (52 [41, 74] vs. 8 [6, 12] days; difference 43, 95% CI 25–62) (p < 0.001 for both). Conclusions: This work highlights the complex medical needs of these infants, requiring prolonged hospitalization and TPN for adequate nutrition. We share our institution’s approach to the nutritional management infants with CF and MI, with a focus on collaboration needed with the multidisciplinary team. Full article
(This article belongs to the Special Issue Innovations in Neonatal and Early Childhood Nutrition)
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25 pages, 650 KB  
Systematic Review
The Relationship Between Children’s Diet and Risk Factors for Cardiovascular Disease
by Claire Butorac, Vadin Bruot, Zane Johnson and Sibylle Kranz
Nutrients 2026, 18(1), 166; https://doi.org/10.3390/nu18010166 - 4 Jan 2026
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Abstract
Background/Objectives The number of children with cardiovascular disease (CVD) risk factors is increasing in the United States. This review summarizes the current knowledge on the relationship between children’s diets and CVD risk factors in children aged 2–18 years. Methods: A systematic literature [...] Read more.
Background/Objectives The number of children with cardiovascular disease (CVD) risk factors is increasing in the United States. This review summarizes the current knowledge on the relationship between children’s diets and CVD risk factors in children aged 2–18 years. Methods: A systematic literature review was conducted using Covidence (PROSPERO registration CRD42024604406) in the three databases PubMed Central, Web of Science, and Embase to include publications published in English between January 2014 and December 2024 that contained the outcome measures total cholesterol, LDL, HDL, triglycerides, and blood pressure. Two independent researchers conducted title, abstract, and full-text screenings; a tiebreaker was used to resolve any conflicts. Risk of bias was assessed using the quality assessment forms included in the Covidence software. Results: Eighty-five studies met the inclusion criteria, and the results were stratified by age group to organize results in a logical manner and increase transparency. Many studies have reported significant relationships, particularly with blood pressure and HDL, but others have found no statistically significant relationships. Conclusions: While a plethora of studies investigating the relationship between diet and CVD risk factors in children are available, the large heterogeneity between the diet factors, diet assessment, outcome measurement methodology, and outcome variable selection varied greatly, affecting the ability to arrive at conclusive results and recommendations. It would be beneficial to develop universally accepted research standards that can be applied to future studies to reduce ambiguity in the understanding of the effect of diet on CVD risk. Full article
(This article belongs to the Special Issue Innovations in Neonatal and Early Childhood Nutrition)
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