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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Alkyne Chemistry
edited by Ruimao Hua
submission deadline 25 Nov 2026 | 9 articles | Viewed by 39041 | Submission Open
Keywords: alkyne annulation; carbocycle synthesis; heterocycle synthesis; atom-economic reaction; synthesis methodology
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Materials Chemistry
edited by , and Mu-Ping Nieh
submission deadline 30 Nov 2026 | 15 articles | Viewed by 30930 | Submission Open
Keywords: materials chemistry; synthetic procedures; characterization procedures; nanomaterials and nanocomposites; biologically oriented materials and biomaterials; materials of natural origin; hybrid composites; mechanical properties; long-term durability
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules—Recent Advances in Computational and Theoretical Chemistry
edited by
submission deadline 30 Nov 2026 | 15 articles | Viewed by 20794 | Submission Open
Keywords: computational chemistry; quantum chemistry; density functional theory; molecular design; reaction mechanism; chemical bonding; non-covalent interactions; molecular docking
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Heterophase Polymerization and Functional Polymer Microspheres/Microcapsules
edited by Chengyou Kan and Wei Deng
submission deadline 30 Nov 2026 | 6 articles | Viewed by 19306 | Submission Open
Keywords: emulsion polymerization; mini emulsion polymerization; dispersion polymerization; suspension polymerization; encapsulation; functionalization; polymer microspheres; microcapsules; characterization; morphology control; structure–property relationship; polymer nanocomposite; application
(This special issue belongs to the Section Materials Chemistry)
Plant Volatile Organic Compounds: Extraction, Characterization and Biological Activities submission deadline 30 Nov 2026 | 7 articles | Viewed by 16263 | Submission Open
Keywords: plant volatile organic compounds; biosynthesis and emission; essential oils; biological activities; green extraction; omics technologies; circular bioeconomy
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Compounds for Brain Ischemia and Neurodegenerative Disease—3rd Edition
edited by and Dalia Marija Kopustinskiene
submission deadline 30 Nov 2026 | 8 articles | Viewed by 12166 | Submission Open
Keywords: brain; neuroprotection; neurodegenerative diseases; ischemia; mitochondria; oxidative stress; inflammation; bioactive compounds
(This special issue belongs to the Section Medicinal Chemistry)
Functional Heterocyclic Compounds with Outstanding Biological Activities submission deadline 30 Nov 2026 | 5 articles | Viewed by 11635 | Submission Open
Keywords: pharmaceutical chemistry; bioactive heterocyclic compounds; antitumor extracts; plant extract–synthetic substances associations; biocompatibility; nontoxicity
(This special issue belongs to the Section Medicinal Chemistry)
Active Ingredients in Functional Foods and Their Impact on Health, 2nd Edition submission deadline 30 Nov 2026 | 7 articles | Viewed by 11088 | Submission Open
Keywords: functional foods; active ingredients; bioactive compounds; health impact; nutraceuticals; dietary patterns; personalized nutrition
(This special issue belongs to the Section Food Chemistry)
Re-Valorization of Waste and Food Co-Products submission deadline 30 Nov 2026 | 9 articles | Viewed by 10454 | Submission Open
Keywords: by-products; valorization; reutilization; zero waste; application of functional ingredients; circular economy
(This special issue belongs to the Section Green Chemistry)
Phytochemistry, Antioxidants, and Anti-Diabetes
edited by , Gordana Rusak and
submission deadline 30 Nov 2026 | 3 articles | Viewed by 8947 | Submission Open
Keywords: bioactive compounds; natural antioxidants; plant extracts; functional foods; nutraceuticals; diabetes
(This special issue belongs to the Section Natural Products Chemistry)
Feature Papers in Applied Chemistry: 4th Edition
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 7446 | Submission Open
Keywords: applied chemistry; new molecules/materials; analytical methods and techniques; electrochemistry and catalysis; new materials and medicines
(This special issue belongs to the Section Applied Chemistry)
A Themed Issue in Honor of the 20th Anniversary of the Mexican Academy of Organic Chemistry (AMQO)
edited by Ivan Romero-Estudillo, , Alicia Boto and
submission deadline 30 Nov 2026 | 7 articles | Viewed by 7327 | Submission Open
Keywords: organic chemistry; chemistry process; chemistry; chemical science; science in Mexico
(This special issue belongs to the Section Organic Chemistry)
Exclusive Feature Papers on Molecular Structure, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 7149 | Submission Open
Keywords: molecular structure; chemical bonding; molecular clusters; molecular similarity; protein structure prediction; quantum chemistry; spectroscopy; molecular dynamics simulations
(This special issue belongs to the Section Molecular Structure)
Applications of EPR Spectroscopy in Various Fields of Scientific Research submission deadline 30 Nov 2026 | 4 articles | Viewed by 6864 | Submission Open
Keywords: EPR spectroscopy; free radicals; paramagnetic species; dosimetry; food technology; archeology; environmental; catalysis
(This special issue belongs to the Section Analytical Chemistry)
Chemical Composition and Biological Evaluation of Essential Oils submission deadline 30 Nov 2026 | 5 articles | Viewed by 6724 | Submission Open
Keywords: essential oils; biological evaluation; chemical composition; therapies; natural products
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Food Compounds and Their Health Benefits submission deadline 30 Nov 2026 | 6 articles | Viewed by 6705 | Submission Open
Keywords: polyphenolic compounds; bioactive compound; natural products; food safety; phytochemicals; carotenoids; LC-MS/MS techniques; HPLC-DAD-MS; fruits, vegetables, and mushrooms; antioxidant compounds; functional food; prebiotics; health benefits
(This special issue belongs to the Section Food Chemistry)
Macromolecular Chemistry in Europe, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 6041 | Submission Open
Keywords: macromolecules; synthesis and polymerization; polymer architectures; properties and structure; functional materials
(This special issue belongs to the Section Macromolecular Chemistry)
Treatment and Analysis of PFAS in Environmental Pollution
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 5681 | Submission Open
Keywords: PFAS; total fluorine; treatment; environmental samples
(This special issue belongs to the Section Green Chemistry)
Current Emerging Trends of Extraction and Encapsulation in Food, 2nd Edition submission deadline 30 Nov 2026 | 5 articles | Viewed by 5511 | Submission Open
Keywords: extraction; encapsulation; drying; emulsion; targeted delivery; stability; bioactive compounds; nonthermal technologies; bioavailability; functional foods
(This special issue belongs to the Section Food Chemistry)
Emerging Contaminants and Their Transformation Products in the Environment: Advanced Analytical Methods for Assessing Ecological and Human Health Impacts
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 4952 | Submission Open
Keywords: emerging contaminants; transformation products; analytical methods; ecological impact; human health risk; contaminant fate; environmental monitoring
(This special issue belongs to the Section Analytical Chemistry)
Review Papers in Physical Chemistry
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 4866 | Submission Open
Keywords: physical chemistry; spectroscopy; quantum chemistry; surface chemistry; molecular dynamics simulations
(This special issue belongs to the Section Physical Chemistry)
The 30th Anniversary of Molecules—Recent Advances in Nanochemistry
edited by
submission deadline 30 Nov 2026 | 5 articles | Viewed by 4848 | Submission Open
Keywords: nanochemistry; nanoscale materials; nanocrystals; nanostructures; nanotubes; nanofabrication; nanomedicine; metal nanoparticles
(This special issue belongs to the Section Nanochemistry)
Phenolic Compounds: Chemistry and Health Benefits submission deadline 30 Nov 2026 | 10 articles | Viewed by 4784 | Submission Open
Keywords: phenolic compounds; polyphenols; antioxidant activity; bioactivity; extraction techniques; chemical characterization; stability; bioavailability; functional foods
(This special issue belongs to the Section Natural Products Chemistry)
Heterocycles in Medicinal Chemistry, 4th Edition
edited by
submission deadline 30 Nov 2026 | 6 articles | Viewed by 4765 | Submission Open
Keywords: drugs; heterocycles; pharmacophore; drug design; computer study; synthesis; analysis; natural compounds; carbohydrates; physicochemical properties; ADMET; biological screening; chemical biology; biological chemistry; biomaterials
(This special issue belongs to the Section Medicinal Chemistry)
Chemical Biology in Asia—Second Edition
edited by and
submission deadline 30 Nov 2026 | 2 articles | Viewed by 4733 | Submission Open
Keywords: chemical biology; drug discovery; bioorganic chemistry; enzymology; synthetic biology; analytical tools
(This special issue belongs to the Section Chemical Biology)
Design and Synthesis of Novel Adsorbents for Pollutant Removal, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 4379 | Submission Open
Keywords: wastewater treatment; adsorbents; sustainable materials; adsorption mechanisms; surface chemistry; selective adsorption
(This special issue belongs to the Section Physical Chemistry)
Innovative Strategies for the Extraction, Processing, and Encapsulation of Food Bioactive Compounds
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 3632 | Submission Open
Keywords: bioactive compounds; extraction techniques; green and sustainable approaches; processing technologies; encapsulation systems; stability and bioavailability; food chemistry and nanotechnology; functional food applications
(This special issue belongs to the Section Food Chemistry)
Advances in Biomaterials: Preparation, Properties and Applications in Biomedicine and Tissue Engineering
edited by and
submission deadline 30 Nov 2026 | 3 articles | Viewed by 3632 | Submission Open
Keywords: biomaterials; decellularized extracellular matrix; tissue engineering; biomedicine; dECM scaffold; bioink; hydrogels
(This special issue belongs to the Section Materials Chemistry)
Effect of Natural Products in the Cancer Therapy Mechanism—2nd Edition
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 3607 | Submission Open
Keywords: anticancer activities; therapeutic potential of plants; phytochemicals; natural products; apoptosis; metastasis; angiogenesis; molecular mechanisms; alkaloids; terpenoids; polyphenols
(This special issue belongs to the Section Chemical Biology)
Chemical Composition and Functional Properties of Food By-Products
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 3469 | Submission Open
Keywords: food by-products; chemical composition; functional properties; antioxidant activity; sustainable food processing
(This special issue belongs to the Section Food Chemistry)
Advances in Electrochemical Reactions, Mechanisms and Sensing Applications submission deadline 30 Nov 2026 | 2 articles | Viewed by 3460 | Submission Open
Keywords: electrochemical reactions; reaction mechanisms; electrocatalysis; electrochemical sensing; organic and organometallic compounds; analytical electrochemistry
(This special issue belongs to the Section Electrochemistry)
Natural Bioactive Compounds: Antioxidant Properties and Associated Biological Activities
edited by
submission deadline 30 Nov 2026 | 5 articles | Viewed by 3415 | Submission Open
Keywords: natural compounds; bioactive compounds; antioxidant activity; biological activities; chemical analysis; structure-function relationships; advanced extraction methods
(This special issue belongs to the Section Natural Products Chemistry)
New Advances in Radiopharmaceutical Sciences, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 3 articles | Viewed by 3208 | Submission Open
Keywords: radiopharmacy/radiopharmaceuticals; radiochemistry; radionuclide therapy; theranostics; PET; SPECT; tadiolabeling techniques; radionuclide production; nuclear medicine
(This special issue belongs to the Section Medicinal Chemistry)
Recent Progress in Environmental Analytical Chemistry submission deadline 30 Nov 2026 | 3 articles | Viewed by 3119 | Submission Open
Keywords: environmental monitoring; water, air and soil pollution; pollution analysis; environmental toxicity; analytical chemistry; chemometrics; method development for analysis of environmental compartments; method validation
(This special issue belongs to the Section Analytical Chemistry)
Analyses and Applications of Phenolic Compounds in Food—3rd Edition submission deadline 30 Nov 2026 | 3 articles | Viewed by 2961 | Submission Open
Keywords: phenolics; extraction; identification; applications in food matrix
(This special issue belongs to the Section Food Chemistry)
Application of Analytical Methods in Food, Drug, and Natural Products Research: 3rd Edition submission deadline 30 Nov 2026 | 4 articles | Viewed by 2952 | Submission Open
Keywords: food characterization; food quality check; natural products’ characterization; natural products’ properties; novel analytical methods in food/natural products analysis; drugs characterization; drugs quality check
(This special issue belongs to the Section Analytical Chemistry)
Essential Oils and Their Derivatives: Characterization, Biological Activity and Application
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 2899 | Submission Open
Keywords: essential oils; aromatic plants; natural products; bioactive compounds; biological activities; pharmacology of volatiles; structure elucidation; isolation techniques
(This special issue belongs to the Section Natural Products Chemistry)
Current Research in Wine Chemistry and Analysis submission deadline 30 Nov 2026 | 2 articles | Viewed by 2824 | Submission Open
Keywords: wine chemistry; analytical methods; sensory properties; phenolic compounds; fermentation chemistry
(This special issue belongs to the Section Food Chemistry)
Advances in Amylases, 2nd Edition
edited by
submission deadline 30 Nov 2026 | 4 articles | Viewed by 2774 | Submission Open
Keywords: enzyme; alpha-amylase enzyme; starch and glycogen; gut microbiome oriented study
(This special issue belongs to the Section Bioorganic Chemistry)
Algal Biomolecules for Food and Pharmaceutical Innovations: Extraction, Characterization and Applications
edited by Renu Geetha Bai
submission deadline 30 Nov 2026 | 1 articles | Viewed by 2641 | Submission Open
Keywords: algal biotechnology; biomass valorization; bioavailability evaluations; advanced extraction and purification techniques; functional and nutraceutical properties
(This special issue belongs to the Section Natural Products Chemistry)
New Achievements and Challenges in Food Chemistry, 2nd Edition
edited by and Qiuming Chen
submission deadline 30 Nov 2026 | 3 articles | Viewed by 2581 | Submission Open
Keywords: food processing innovations; alternative proteins; bioactive compounds; food safety; food storage; flavor chemistry; food enzyme design; AI-assisted technologies; novel analytical methods
(This special issue belongs to the Section Food Chemistry)
Physical–Chemical Interactions and Composition–Structure–Property Modifications During Food Processing submission deadline 30 Nov 2026 | 1 articles | Viewed by 2508 | Submission Open
Keywords: structure; food; thermal properties; chemical composition
(This special issue belongs to the Section Food Chemistry)
Plasmonic Metal Nanoparticles: From Synthesis to Major Applications
edited by
submission deadline 30 Nov 2026 | 1 articles | Viewed by 2499 | Submission Open
Keywords: metal nanoparticles and nanoclusters; plasmonic metal nanoparticles; metal nanocomposites; shape-selected synthesis; size-selected synthesis; functional properties; high-resolution electron microscopy; surface plasmon resonance; interfacial properties; surface modification; catalysis; plasmonics; surface-enhanced Raman scattering; biomedical sensing; environmental sensing
(This special issue belongs to the Section Physical Chemistry)
Advances in Organic Materials for Energy, Optoelectronics, and Electronics submission deadline 30 Nov 2026 | 2 articles | Viewed by 2290 | Submission Open
Keywords: organic semiconductors; perovskites; solar cells; LEDs; lasers; microcavities; photodetectors; optoelectronics
(This special issue belongs to the Section Applied Chemistry)
Bioactive Phytochemicals from Plants: Pharmacological and Therapeutic Applications submission deadline 30 Nov 2026 | 3 articles | Viewed by 2154 | Submission Open
Keywords: bioactive phytochemicals; medicinal plants; natural products; pharmacological activity; therapeutic applications; antioxidant compounds
(This special issue belongs to the Section Natural Products Chemistry)
Pharmacological Bioassays of Secondary Metabolites of Medicinal Plants submission deadline 30 Nov 2026 | 1 articles | Viewed by 2060 | Submission Open
Keywords: pharmacology of medicinal plants; pharmacology of natural products; medicinal plants; mechanisms of action (cardiovascular, nervous system, digestive, etc.); active principles in diseases (Parkinson's, cancer, ulcers, etc.); isolation and bioassays of medicinal plant extracts
(This special issue belongs to the Section Natural Products Chemistry)
Antibacterial Agents from Natural Source, 3rd Edition submission deadline 30 Nov 2026 | 1 articles | Viewed by 2038 | Submission Open
Keywords: natural products; antibacterial activity; anti-virulence; bioactive molecules; mechanisms and applications; biological activity; drug development; antibacterial peptides
(This special issue belongs to the Section Natural Products Chemistry)
Bioactive Natural Products: Isolation, Modification, and Therapeutic Potential submission deadline 30 Nov 2026 | 1 articles | Viewed by 1901 | Submission Open
Keywords: bioactive natural products; extraction; isolation; chemical modification; pharmacological activity; structure–activity relationships; bioavailability; therapeutic potential
(This special issue belongs to the Section Natural Products Chemistry)
Molecular Modeling: Advancements and Applications, 4th Edition
edited by
submission deadline 30 Nov 2026 | 3 articles | Viewed by 1648 | Submission Open
Keywords: quantum mechanics; molecular mechanics (MM); molecular dynamics (MD); semi-empirical calculations; ab initio methods; post-Hartree–Fock methods; density functional theory (DFT); software development; achieving chemical accuracy; thermochemistry and reactivity; interaction energy; covalent bonding and non-covalent interactions; large molecular systems; IR, Raman, and NMR; drug design; nanomaterials and nanotechnology; material sciences
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Zeolites and Related Nanoporous Materials: Green Supports for Molecules
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 1572 | Submission Open
Keywords: porous materials; zeolites; selective catalysts; zeolite-like materials; molecule selectivity
(This special issue belongs to the Section Materials Chemistry)
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