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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Product Leads for Managing Metabolic Diseases submission deadline 30 Jan 2027 | Viewed by 365 | Submission Open
Keywords: diabetes; metabolic syndrome; metabolic diseases; natural products; mechanisms; drug discovery
(This special issue belongs to the Section Natural Products Chemistry)
Featured Reviews in Bioorganic Chemistry submission deadline 30 Jan 2027 | Viewed by 298 | Submission Open
Keywords: bioorganic chemistry; enzyme inhibitors; biocatalysis; biosynthesis; immunochemical techniques; membrane chemistry; peptides chemistry
(This special issue belongs to the Section Bioorganic Chemistry)
Recent Progress in Small-Molecule Inhibitors: Novel Targets and Emerging Chemical Modalities
edited by and Nirmitee Mulgaonkar
submission deadline 30 Jan 2027 | Viewed by 14 | Submission Open
Keywords: small-molecule inhibitors; PROTAC; RIPTAC; immunomodulator; kinase inhibitors; molecular glue
(This special issue belongs to the Section Chemical Biology)
Bio-Based and Natural Compounds: A Sustainable Approach for an Environmental Transition submission deadline 31 Jan 2027 | 7 articles | Viewed by 12191 | Submission Open
Keywords: bio-based materials; green materials; environmental application; natural compounds; characterization; sustainability
(This special issue belongs to the Section Green Chemistry)
Natural-Based Sorbents for Water Remediation submission deadline 31 Jan 2027 | 4 articles | Viewed by 6530 | Submission Open
Keywords: natural sorbents; removal of organic or inorganic contaminants from water; physical and chemical characterization of the sorbent; kinetic and equilibrium sorptive tests; evaluation of thermodynamic and kinetic parameters; determination of the actual sorption mechanism
(This special issue belongs to the Section Physical Chemistry)
Natural Extracts for Pharmaceutical Applications
edited by
submission deadline 31 Jan 2027 | 4 articles | Viewed by 6336 | Submission Open
Keywords: natural compounds; phytochemicals; bioactive compounds; medicinal plants; phytopharmacology; antioxidant activity; anti-inflammatory; antimicrobial; antidiabetic; wound healing
(This special issue belongs to the Section Medicinal Chemistry)
Analytical Chemistry in Europe: Towards Sustainability and Quality of Life, 3rd Edition submission deadline 31 Jan 2027 | 4 articles | Viewed by 5919 | Submission Open
Keywords: analytical and bioanalytical methods; chemistry; drugs; toxic compounds; biomarkers; sample preparation; life quality; sustainability
(This special issue belongs to the Section Analytical Chemistry)
Inorganic Chemistry in Asia, 2nd Edition
edited by
submission deadline 31 Jan 2027 | 5 articles | Viewed by 5875 | Submission Open
Keywords: inorganic chemistry; coordination chemistry; organometallic chemistry; solid-state chemistry; bioinorganic chemistry; nuclear- and radiochemistry; theoretical calculation
(This special issue belongs to the Section Inorganic Chemistry)
Advances in Plant-Based Materials
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 5798 | Submission Open
Keywords: isolation; investigation; plant compounds; bioactive activity; extraction techniques; chromatographic techniques; electromigrational techniques
(This special issue belongs to the Section Natural Products Chemistry)
Pharmaceuticals in the Environment: Micropollutants and Degradation Dynamics
edited by Agnieszka Nowak and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 5573 | Submission Open
Keywords: pharmaceuticals; microorganisms; toxicity; micropollutants; biodegradation; biotransformation; advanced oxidation processes; analysis; intermediate identification; chromatography
(This special issue belongs to the Section Green Chemistry)
Bioactive Compounds in Food: Extraction and Characterization submission deadline 31 Jan 2027 | 4 articles | Viewed by 4909 | Submission Open
Keywords: bioactive compounds; food matrices; extraction techniques; green technologies; analytical characterization; structural elucidation; stability and bioavailability; functional food applications
(This special issue belongs to the Section Food Chemistry)
Quantum Chemistry in Modern Science: Chemical Bonding, Spectroscopy, and Beyond
edited by Isuru R. Ariyarathna
submission deadline 31 Jan 2027 | 4 articles | Viewed by 4816 | Submission Open
Keywords: quantum chemistry; ab initio multireference methods; coupled-cluster; density functional theory; spectroscopy; chemical bonding; transition metals; lanthanides; actinides
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Rational Design, Synthesis, and Evaluation of Small-Molecule Anticancer Agents
edited by and Ganga Reddy Velma
submission deadline 31 Jan 2027 | 3 articles | Viewed by 4780 | Submission Open
Keywords: drug design; medicinal chemistry; organic synthesis; total synthesis; multi-drug resistance; biological activity; anti-cancer; heterocyclic compounds; cytotoxicity; structure–activity relationship; molecular modeling
(This special issue belongs to the Section Medicinal Chemistry)
Carbon-Based Materials for Sustainable Chemistry: 3rd Edition
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 4429 | Submission Open
Keywords: carbon-based materials; carbon nanostructures; adsorption; sustainability
(This special issue belongs to the Section Materials Chemistry)
Applications of Natural Polymers in Biomedicine submission deadline 31 Jan 2027 | 3 articles | Viewed by 4214 | Submission Open
Keywords: polymer biomaterials; biopolymers; proteins; polysaccharides; gels; hydrogels; scaffolds; films
(This special issue belongs to the Section Medicinal Chemistry)
Lignin Valorization in Biorefineries
edited by Carlos Eduardo De Araújo Padilha, Everaldo Silvino Dos Santos and Domingos Fabiano de Santana Souza
submission deadline 31 Jan 2027 | 3 articles | Viewed by 3853 | Submission Open
Keywords: pretreatment; bioactive compounds; antioxidant properties; kraft lignin; extraction; thermochemical processes
(This special issue belongs to the Section Green Chemistry)
Review Papers in Materials Chemistry—2nd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 3376 | Submission Open
Keywords: materials chemistry; organic and inorganic materials; biomaterials; nanomaterials; hybrid materials; core-shell materials; thin films; self-assembling systems; tailored and unusual properties of materials
(This special issue belongs to the Section Materials Chemistry)
Corrosion Mechanisms and Protection Technologies of Metallic Materials Under Harsh Environments
edited by Baojun Dong, , Dezhi Zeng and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 3210 | Submission Open
Keywords: metal coating; non-metal coating; coating design and preparation; coating performance evaluation; corrosion mechanism in harsh environments
(This special issue belongs to the Section Materials Chemistry)
Porous Organic Materials: Design and Applications, 3rd Edition
edited by and Qi Chen
submission deadline 31 Jan 2027 | 2 articles | Viewed by 3132 | Submission Open
Keywords: topology design; synthesis; structure−function correlation; adsorption and separation; catalysis; energy storage and conversion; mass transportation; biological application
(This special issue belongs to the Section Materials Chemistry)
Selectivity and Theoretical Studies of Cycloaddition Reactions
edited by , and Ewa Dresler
submission deadline 31 Jan 2027 | 2 articles | Viewed by 3067 | Submission Open
Keywords: cycloaddition; selectivity; density functional theory (DFT); reaction mechanisms; catalysis; stereocontrol
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Extraction, Chromatography, and Mass Spectrometry Analysis of Food and Plant Biomolecules submission deadline 31 Jan 2027 | 1 articles | Viewed by 3031 | Submission Open
Keywords: liquid chromatography; gas chromatography; sample preparation; extraction; supercritical fluid extraction; solid-phase extraction; liquid–liquid extraction
(This special issue belongs to the Section Analytical Chemistry)
Natural and Sustainable Emulsions: Design, Stabilization, and Functional Applications submission deadline 31 Jan 2027 | 1 articles | Viewed by 2850 | Submission Open
Keywords: natural emulsifiers; pickering emulsions; biopolymer stabilization; microencapsulation; sustainable formulations; bio-based materials
(This special issue belongs to the Section Materials Chemistry)
Biopolymer-Based Materials: Preparation, Properties and Applications
edited by
submission deadline 31 Jan 2027 | 4 articles | Viewed by 2815 | Submission Open
Keywords: biopolymer; biopolymer based; material; preparation; processing; characterization; modification; physicochemical; mechanical; application; packaging; biomedical engineering; agriculture; environmental remediation
(This special issue belongs to the Section Green Chemistry)
Circular Economy: Agri-Food Byproducts as Source of Bioactive Compounds, 2nd Edition submission deadline 31 Jan 2027 | 4 articles | Viewed by 2742 | Submission Open
Keywords: agri-food byproducts; plant extracts; food extracts; essential oils; bioactive compounds; nutraceuticals; micromorphology; phytochemistry; health effects; eco-sustainability
(This special issue belongs to the Section Green Chemistry)
Ligand-Based Design and Optimization of Antibacterial Agents: From Structure to Activity submission deadline 31 Jan 2027 | 2 articles | Viewed by 2717 | Submission Open
Keywords: ligand-based drug design (LBDD); antibacterial agents; quantitative structure–activity relationship (QSAR); pharmacophore modeling; virtual screening; cheminformatics; molecular optimization
(This special issue belongs to the Section Medicinal Chemistry)
Development of Active Bio-Packaging Films for Food Industry with Natural Bioactive Compounds
edited by Renata Dobrucka
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2596 | Submission Open
Keywords: active packaging; natural compounds; biomaterials; biocomposites; natural polymers; polysaccharides; packaging materials
(This special issue belongs to the Section Materials Chemistry)
Modern Sample Preparation Approaches for Separation Science, 2nd Edition
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2541 | Submission Open
Keywords: sample preparation; enrichment techniques; sorption-based methods; virtual sample preparation; microextraction techniques; new analytical strategies; separation techniques
(This special issue belongs to the Section Analytical Chemistry)
Advances in European Materials Chemistry submission deadline 31 Jan 2027 | 2 articles | Viewed by 2449 | Submission Open
Keywords: carbon-based materials; nanomaterials; nuclear materials; luminescent materials; textile materials; biomaterials; interfaces in material systems; hybrid organic–inorganic materials; thin films and coatings; self-assembling systems; nanocomposites; thermal behavior; durability
(This special issue belongs to the Section Materials Chemistry)
Advances in Molecular Modeling in Chemistry, 3rd Edition
edited by
submission deadline 31 Jan 2027 | 3 articles | Viewed by 2436 | Submission Open
Keywords: molecular modeling; applications; quantum chemistry calculation; molecular dynamic simulation; Monte Carlo simulation; combined experimental and simulation studies
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Design of Chemically Recyclable Polymers in Sustainable Chemistry: A Minimalist Perspective
edited by Francesco Stellacci, Youwei Ma and Ping Yu
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2418 | Submission Open
Keywords: chemically recyclable polymers; sustainable polymers; biomass-based polymers; dynamic (covalent) bonds; minimalist sustainable design
(This special issue belongs to the Section Green Chemistry)
Hybrid and Hierarchical Zeolite-Based Platforms for Sustainable Remediation and Resource Recovery
edited by and
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2190 | Submission Open
Keywords: hybrid and hierarchical zeolite-based materials; environmental remediation technologies; PFAS and emerging persistent pollutants; water, air, and soil treatment; functional porous platforms; natural, synthetic, composite, and nano-zeolites; structure–contaminant interaction mechanisms; circular economy and sustainable applications
(This special issue belongs to the Section Materials Chemistry)
Unlocking the Potential of Agro-Forestry Residues: Biomolecules for Diverse Applications and Multifunctional Uses submission deadline 31 Jan 2027 | 3 articles | Viewed by 2032 | Submission Open
Keywords: waste management; recycling; lignin; tannins; cellulose; additives; eco-friendly materials; nanotechnology; sustainability; circular economy
(This special issue belongs to the Section Green Chemistry)
Recent Research on Photocatalysis for Energy Storage and Conversion submission deadline 31 Jan 2027 | 1 articles | Viewed by 1993 | Submission Open
Keywords: photocatalyst; photo/electrocatalyst; energy storage and conversion; photogenerated carrier; carbon neutrality; semiconductors
(This special issue belongs to the Section Photochemistry)
Nutritional Enhancement and Functional Innovation of Plant-Based Foods submission deadline 31 Jan 2027 | 1 articles | Viewed by 1962 | Submission Open
Keywords: plant-based foods; plant product bioavailability; vegan diet; nutritional enhancement; functional innovation; protein fortification; sustainable nutrition
(This special issue belongs to the Section Food Chemistry)
Green Valorization of Food By‑Products: Bioactive Molecules and Food‑Grade Delivery Systems submission deadline 31 Jan 2027 | 2 articles | Viewed by 1906 | Submission Open
Keywords: valorization; food; agro‑industrial by‑product; fruit; vegetable; botanical; delivery; encapsulation; extraction; characterization; cold pressing; pressurized liquids; ultrasound; microwave; supercritical; subcritical; phenolic; terpene; lipid; peptide; polysaccharide; purification; structure–activity relationship; bioefficacy; antioxidant; antimicrobial; anti‑inflammatory; spray‑dried microcapsule; complex coacervate; nanoemulsion; cyclodextrin inclusion complex; ionotropic gelation system; controlled release; nutraceutical; active packaging; circular‑bioeconomy metrics; shelf‑life; in silico
(This special issue belongs to the Section Food Chemistry)
Advanced Approaches for Analysis of Food Contaminants and Residues submission deadline 31 Jan 2027 | 1 articles | Viewed by 1885 | Submission Open
Keywords: allergens in foods; antibiotics in food products; endocrine-disrupting substances; food additives; food contact materials; mycotoxins; pesticides; polyaromatic hydrocarbons (PAH); process-induced changes and oxidation products
(This special issue belongs to the Section Analytical Chemistry)
Advances in Porphyrinoid-Based Functional Materials submission deadline 31 Jan 2027 | 1 articles | Viewed by 1854 | Submission Open
Keywords: porphyrinoids; synthetic approaches; functional materials; medicine; environment; energy; sensing; catalysis
(This special issue belongs to the Section Organic Chemistry)
Advanced Analytical Techniques for the Detection and Quantification of Emerging Contaminants, 2nd Edition submission deadline 31 Jan 2027 | 2 articles | Viewed by 1833 | Submission Open
Keywords: extraction protocols; method development; determination of emerging contaminants; fate and transformation of contaminants; environmental monitoring; advanced separation techniques; high-resolution mass spectrometry; identification workflows
(This special issue belongs to the Section Analytical Chemistry)
Computational Design of Nanomaterials for Environmental and Biomedical Applications submission deadline 31 Jan 2027 | 1 articles | Viewed by 1714 | Submission Open
Keywords: computational nanomaterials design; molecular modeling and simulation; machine learning in materials science; environmental remediation nanomaterials; nanomedicine and drug delivery; biocompatibility and safety assessment; quantum chemistry and multiscale modeling; sustainable nanotechnology
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Natural Products: Isolation, Analysis and Biological Activity, 3rd Edition submission deadline 31 Jan 2027 | 3 articles | Viewed by 1615 | Submission Open
Keywords: essential oils; plant extracts; biological activities; antiproliferative activity; enzymatic inhibitor activity; phytotoxic activity; bioactive compounds in natural products; secondary metabolites; structure–activity relationships; antimicrobial activity; phytopathogens
(This special issue belongs to the Section Natural Products Chemistry)
Recent Advances on Biomass Conversion and CO2 Valorization: Steeping Towards a Circular Economy, 2nd Edition
edited by and Eva Castillejos-Lopéz
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1486 | Submission Open
Keywords: CO2 valorization; biomass conversion; catalysis
(This special issue belongs to the Section Green Chemistry)
Application of Vibrational Spectroscopy Coupled with Chemometric Tools submission deadline 31 Jan 2027 | 2 articles | Viewed by 1480 | Submission Open
Keywords: vibrational spectroscopy; chemometrics; quantitative analysis; qualitative analysis; NIR spectroscopy; IR spectroscopy; Raman spectroscopy
(This special issue belongs to the Section Analytical Chemistry)
Green Chemistry Approaches to Analysis and Environmental Remediation—2nd Edition
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 1412 | Submission Open
Keywords: chromatography; mass spectrometry; extraction; green analytical chemistry; emerging contaminants
(This special issue belongs to the Section Analytical Chemistry)
Essential Oils: Chemical Characterization, Bioactivity and Innovative Applications
edited by and Florin Imbrea
submission deadline 31 Jan 2027 | 2 articles | Viewed by 1171 | Submission Open
Keywords: essential oils; phytochemistry; green extraction technologies; bioactivity; antimicrobial activity; antibiofilm activity; antimicrobial resistance; antioxidant activity; nanoencapsulation; molecular docking; therapeutic potential; alternative medicine; functional foods; food preservation; biopesticides; sustainable agriculture; natural bioactive compounds; novel delivery systems
(This special issue belongs to the Section Natural Products Chemistry)
Chemical and Functional Characterization of Novel Plant Proteins
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 986 | Submission Open
Keywords: novel plant proteins; chemical characterization; functional properties; protein structure–function relationships; extraction and modification techniques; techno-functional behavior; protein digestibility and bioactivity; sustainable protein sources
(This special issue belongs to the Section Food Chemistry)
Microbe Metabolites as Functional and Bioactive Components in Food
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 977 | Submission Open
Keywords: microbial metabolites; functional food; bioactive compounds; fermentation; gut microbiota; single-cell protein; microbial lipids; natural pigments; probiotics
Production of Artemisia and Its Pharmacology vs. Artemisinin
edited by and Yuliang Wang
submission deadline 31 Jan 2027 | 1 articles | Viewed by 975 | Submission Open
Keywords: Artemisia annua; Artemisia afra; synergism; infectious and chronic diseases; phytochemistry; artemisinin biosynthesis
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Optoelectronic Functional Materials: From Fundamental Innovation to Cutting-Edge Applications
edited by Fuquan Bai
submission deadline 31 Jan 2027 | 1 articles | Viewed by 871 | Submission Open
Keywords: design; synthesis; characterization; application; theoretical; optoelectronic functional material; perovskite solar cell; 2D material; graphene; TMDs; heterostructure; photodetector; flexible electronics; sensor; quantum dot; LED
(This special issue belongs to the Section Materials Chemistry)
Natural Products Chemistry in the Americas
edited by Margarete Zanardo Gomes, and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 839 | Submission Open
Keywords: natural products chemistry; bioactive compounds; extraction techniques; biological applications; biodiversity in the Americas; sustainable bioprospecting; pharmaceutical potential
(This special issue belongs to the Section Natural Products Chemistry)
Biochemically Active Natural and Semisynthetic Products: Extraction, Characterization, and Application—2nd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 824 | Submission Open
Keywords: natural and semisynthetic products; extraction, isolation, and purification; identification and structural elucidation; biological properties; multidisciplinary applications
(This special issue belongs to the Section Natural Products Chemistry)
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