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Bio-Based and Natural Compounds: A Sustainable Approach for an Environmental Transition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 1009

Special Issue Editors


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Guest Editor
School of Science and Technology, Chemistry Division, University of Camerino, 62032 Camerino, Italy
Interests: environmental chemistry; environmental remediation; photocatalysis; metal nanoparticles; nanomaterials; sensors; SERS; DSSC; porphyrins; dyes; graphene; organic and inorganic pollutants; natural compounds
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
School of Science and Technology, Chemistry Division, University of Camerino, 62032 Camerino, Italy
Interests: environmental chemistry; environmental remediation; photocatalysis in water treatment; metal nanoparticles; natural compounds’ characterization; nanomaterials; optical sensors; SERS; porphyrins; graphene; organic and inorganic pollutants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Currently, the need to address environmental challenges has become increasingly clear and important.

Our planet is facing a great threat, with solutions that are innovative, courageous, green, and having a low environmental impact being required. A promising and important solution concerns the development and adoption of bio-based and biodegradable products.

New materials and processes will need to avoid the use of high-environmental-impact compounds and non-biodegradable materials, such as plastic. The replacement of conventional products with bio-based materials/compounds will be necessary in the long term.

For example, organic molecules derived from renewable biomass sources, such as organic, agricultural or forestry wastes, are known as bio-based chemicals; these eco-friendly alternatives to traditional petroleum-based chemicals can find applications in a wide range of sectors: green chemistry, environmental remediation, manufacturing, personal care, packaging, agriculture and as biofuels.

Finally, the application of bio-based compounds can facilitate the creation of a circular economy through the continuous recycling of renewable resources.

In this context, we welcome the submissions of manuscript to this Special Issue that aim to collect contributions on bio-based and sustainable materials with different applications, alternative natural chemical compounds and their characterization, and bio-based compounds and materials used in environmental applications.

Dr. Marco Zannotti
Dr. Rita Giovannetti
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bio-based materials
  • green materials
  • environmental application
  • natural compounds
  • characterization
  • sustainability

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Published Papers (2 papers)

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Research

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30 pages, 3245 KB  
Article
The Effect of Organic Materials on the Response of the Soil Microbiome to Bisphenol A
by Magdalena Zaborowska, Jadwiga Wyszkowska, Mirosława Słaba, Agata Borowik, Jan Kucharski and Przemysław Bernat
Molecules 2025, 30(19), 3868; https://doi.org/10.3390/molecules30193868 - 24 Sep 2025
Abstract
In view of the increasing environmental pollution caused by bisphenol A (BPA), understanding its impact on the microbiological properties of soil, which play a key role in maintaining soil fertility and consequently ecosystem stability, is particularly important. Therefore, the aim of this study [...] Read more.
In view of the increasing environmental pollution caused by bisphenol A (BPA), understanding its impact on the microbiological properties of soil, which play a key role in maintaining soil fertility and consequently ecosystem stability, is particularly important. Therefore, the aim of this study was to assess the sensitivity of the soil microbiome to this xenobiotic and to evaluate the potential of organic materials such as starch (St), grass compost (Co), and fermented bark (B) to restore the balance of soil cultivated with Zea mays. The negative effects of BPA on the abundance, diversity, and structure of bacterial and fungal communities in soil contaminated with 500 and 1000 mg kg−1 d.m. of soil were confirmed. Changes in the phospholipid profile, including phosphatidylethanolamine (PE), phosphatidylcholine (PC), phosphatidylglycerol (PG), and ergosterol (E), were also assessed. BPA applied at 1000 mg kg−1 d.m. of soil inhibited the proliferation of organotrophic bacteria and actinomycetes, while stimulating fungal growth. This xenobiotic’s impact is also reflected by a decrease in PC and PG levels in soil under BPA pressure. Through amplification of the V3-V4 16S rRNA region (for bacteria) and the ITS1 region (for fungi), the dominant bacterial phylum Proteobacteria was identified, with genera including Cellulosimicrobium, Caulobacter, Rhodanobacter, Sphingomonas, Mucilaginibacter, and Pseudomonas. Among fungi, Ascomycota dominated, primarily represented by the genus Penicillium. Of all the organic materials tested for mitigating BPA’s negative effects, grass compost was identified as the most promising, not only restoring soil homeostasis but also enhancing the growth and development of Zea mays cultivated in BPA-contaminated soil. Full article
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Review

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27 pages, 1053 KB  
Review
Critical Review Regarding the Application of Plant Extracts as Eco-Friendly Corrosion Inhibitors—A Sustainable Interdisciplinary Approach
by Catalin Alexandru Barbu, Irina Fierascu, Augustin Semenescu and Cosmin M. Cotrut
Molecules 2025, 30(18), 3722; https://doi.org/10.3390/molecules30183722 - 12 Sep 2025
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Abstract
Corrosion remains a persistent and costly issue across multiple industrial domains, including infrastructure, transportation, and marine operations. The deterioration of metals and alloys under corrosive conditions results in significant financial losses and poses considerable environmental and safety risks. Although traditional corrosion inhibitors demonstrate [...] Read more.
Corrosion remains a persistent and costly issue across multiple industrial domains, including infrastructure, transportation, and marine operations. The deterioration of metals and alloys under corrosive conditions results in significant financial losses and poses considerable environmental and safety risks. Although traditional corrosion inhibitors demonstrate high efficacy, they often contain toxic, synthetic compounds that endanger both human health and ecological systems. The increasing global focus on environmental responsibility and green chemistry has intensified the demand for alternative, non-toxic corrosion mitigation strategies. This review examines the use of plant extracts obtained through various processing methods as “environmentally friendly”, responsible corrosion inhibitors. This analysis underscores the capacity of plant-based compounds to counteract material degradation across diverse applications, from technologically advanced industrial systems to the preservation of cultural heritage. Through an interdisciplinary perspective, this review evaluates the viability of botanical approaches as sustainable substitutes for conventional inhibitors, contributing to a broader understanding of their potential across distinct fields. Full article
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