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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biopolymers for Drug Delivery Systems, 2nd Edition
edited by and Petra Arany
submission deadline 31 Jan 2027 | Viewed by 226 | Submission Open
Keywords: drug delivery systems; biopolymers; personalized medication; nanoparticle; hydrogel; 3D printing
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances of Nanomaterials in Electrochemistry
edited by Najeeb Lashari
submission deadline 31 Jan 2027 | Viewed by 220 | Submission Open
Keywords: nanomaterials; electrochemistry; nanostructured electrodes; electrocatalysis; energy storage; batteries; supercapacitors; electrochemical sensors; nanocomposites; two-dimensional materials; transition metal oxides; carbon nanomaterials; conductive polymers; interface engineering; charge transport; photoelectrochemistry; green energy technologies; surface chemistry; nano-electrocatalysts; advanced functional materials
(This special issue belongs to the Section Nanochemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems—2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 216 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipid capsules
(This special issue belongs to the Section Food Chemistry)
Phenolic Compounds from Foods: Extraction, Characterization, and Biological Activity submission deadline 31 Jan 2027 | Viewed by 212 | Submission Open
Keywords: phenolic compounds; food extracts; extraction techniques; chemical characterization; biological activity; antioxidant properties
(This special issue belongs to the Section Food Chemistry)
Chemical Characterisation and Biological Evaluation of Bioactive Extracts and Functional Ingredients from Agro-Food By-Products
edited by Anca Becze
submission deadline 31 Jan 2027 | Viewed by 204 | Submission Open
Keywords: agro-food by-products; compositional profiling; bioactive compounds; extraction and valorisation; functional food ingredients; antioxidant and antimicrobial activity
(This special issue belongs to the Section Food Chemistry)
Carbon-Based Nanomaterials and Their Applications
edited by Naveen Kumar Reddy Bogireddy, Juan Horacio Pacheco-Sánchez and Claudia Rosario Muro-Urista
submission deadline 31 Jan 2027 | Viewed by 204 | Submission Open
Keywords: carbon nanomaterials; graphene; carbon nanotubes; fullerenes; graphyne; diamond-like carbon; carbon dots; molecular dynamics; density functional theory; Monte Carlo simulation; multiscale modeling; catalysis; photocatalysis; adsorption; CO2 capture; hydrogen storage; energy storage; supercapacitors; wastewater treatment; environmental remediation; sustainable materials; nanocomposites; gas separation; porous carbon materials; green synthesis
(This special issue belongs to the Section Materials Chemistry)
Ionic Liquids and Deep Eutectic Solvents for Pharmaceutical Analysis
edited by and Branislava Teofilović
submission deadline 31 Jan 2027 | Viewed by 192 | Submission Open
Keywords: ionic liquids; deep eutectic solvents; physicochemical analysis; green extraction and separation; phytochemicals; pharmaceutical analysis; chromatographic analysis; active pharmaceutical ingredients
(This special issue belongs to the Section Analytical Chemistry)
Aromatic Heterocyclic Compounds: From Synthesis to Biological Activities Research submission deadline 31 Jan 2027 | Viewed by 179 | Submission Open
Keywords: aromatic heterocycles; organic synthesis; medicinal chemistry; bioactive scaffolds; SAR; synthetic methodologies
(This special issue belongs to the Section Organic Chemistry)
Emerging Natural Antioxidants for Food Storage and Functional Food Innovation submission deadline 31 Jan 2027 | Viewed by 179 | Submission Open
Keywords: natural antioxidants; food storage; functional food; food safety; shelf life
(This special issue belongs to the Section Food Chemistry)
Biologically-Derived Nanomaterials: Synthesis, Functionalization and Applications in Environmental and Circular Technologies
edited by , and
submission deadline 31 Jan 2027 | Viewed by 176 | Submission Open
Keywords: green synthesis; nanomaterials; biomass-derived materials; water treatment; environmental remediation; circular economy; photocatalysis; waste valorisation
(This special issue belongs to the Section Nanochemistry)
Advanced Metal-Based Drug Formulations in Cancer Treatment
edited by Sanja A. Mijatović and
submission deadline 31 Jan 2027 | Viewed by 168 | Submission Open
Keywords: metal-based drugs; chemotherapy; cancer; tumor microenvironment; hybrid molecules; drug design; anticancer activity; drug delivery; tumor resistance
(This special issue belongs to the Section Medicinal Chemistry)
Biomaterials and Bioactive Systems: From Synthesis to Biomedical Applications
edited by Pedro M.G. Nicolau, and
submission deadline 31 Jan 2027 | Viewed by 164 | Submission Open
Keywords: biomaterials; bioactive systems; tissue engineering; drug delivery; biomedical applications
(This special issue belongs to the Section Cross-Field Chemistry)
New Insights into Maillard Reaction
edited by Junjian Miao and
submission deadline 31 Jan 2027 | Viewed by 157 | Submission Open
Keywords: Maillard reaction; advanced glycation end-products (AGEs); food chemistry; flavor formation; non-enzymatic browning; acrylamide mitigation; reaction kinetics; nutritional impact; bioactive compounds; food processing
(This special issue belongs to the Section Flavours and Fragrances)
Research Advances in Rotational Spectroscopy: From Structures to Large Amplitude Motions of Molecules
edited by
submission deadline 31 Jan 2027 | Viewed by 146 | Submission Open
Keywords: rotational spectroscopy; microwave spectroscopy; large amplitude motion; structure determination; non-covalent interaction; nuclear quadrupole coupling
(This special issue belongs to the Section Molecular Structure)
Advances on Plant Extracts: Antioxidant and Anticancer Properties
edited by
submission deadline 31 Jan 2027 | Viewed by 143 | Submission Open
Keywords: plant extracts; antioxidants; free radicals; oxidative stress; melanin biopolymers; cancer; UV-Vis spectrophotometry; EPR spectroscopy
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Terpenes and Terpene Derivatives
edited by Xin Hua, and
submission deadline 31 Jan 2027 | Viewed by 142 | Submission Open
Keywords: terpenes; terpenoids; natural products; biosynthesis; synthetic biology; enzyme characterization; metabolic engineering; structural elucidation; bioactivity; chemical synthesis
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Conductive Composite Materials
edited by , and Ilaria Improta
submission deadline 31 Jan 2027 | Viewed by 122 | Submission Open
Keywords: conductive composite materials; polymer nanocomposites; conductive fillers; carbon nanotubes (CNTs); graphene; MXenes; hybrid nanocomposites; smart textiles; interfacial engineering; structure–property relationships
(This special issue belongs to the Section Materials Chemistry)
Natural Products: Extraction, Analysis and Biological Activities: 2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 117 | Submission Open
Keywords: plant products; secondary metabolites; extraction; analysis; quality of natural products; biological activity; health-promoting properties; agricultural waste
(This special issue belongs to the Section Natural Products Chemistry)
Innovations in Catalysts for Hydrogen Evolution Reactions
edited by Socorro Oros-Ruiz
submission deadline 31 Jan 2027 | Viewed by 116 | Submission Open
Keywords: hydrogen evolution reaction; electrocatalysis; green hydrogen; metal nanoparticles; carbon-supported catalysis; metal organic frameworks (MOFs); nanomaterials; heterostructures; water splitting; photoreforming; artificial photosynthesis; catalysts design
(This special issue belongs to the Section Materials Chemistry)
Natural Products in Anticancer Activity: 3rd Edition
edited by Luciana Scotti
submission deadline 31 Jan 2027 | Viewed by 106 | Submission Open
Keywords: natural products; anticancer; drug; nature; molecule
(This special issue belongs to the Section Natural Products Chemistry)
Application of Advanced Materials in Green Catalysis
edited by Francesca Coccia
submission deadline 31 Jan 2027 | Viewed by 102 | Submission Open
Keywords: green catalysis; advanced materials; catalytic materials; environmental remediation; renewable resources; sustainable synthesis; biomass valorization
(This special issue belongs to the Section Materials Chemistry)
Molecular Structure and Dynamics: Spectroscopy, Calorimetry, and Applications submission deadline 31 Jan 2027 | Viewed by 83 | Submission Open
Keywords: molecular structure; molecular dynamics; spectroscopy; calorimetry; intermolecular interactions; ligand-protein interactions; antioxidant protein
(This special issue belongs to the Section Physical Chemistry)
Functional Heterocycles: Sustainable Synthesis and Biological Applications submission deadline 31 Jan 2027 | Viewed by 79 | Submission Open
Keywords: heterocyclic compounds; sustainable synthesis; catalytic transformations; asymmetric synthesis; medicinal chemistry; biologically active compounds; functional organic materials; fluorescent probes; green chemistry
(This special issue belongs to the Section Organic Chemistry)
Recent Advances in Mass Spectrometry-Based Analysis and Bioanalysis submission deadline 31 Jan 2027 | Viewed by 78 | Submission Open
Keywords: mass spectrometry; chromatography; bioanalysis; metabolomics; proteomics
(This special issue belongs to the Section Analytical Chemistry)
The Mpemba Effect: Experiment & Theory
edited by Alexei Finkelstein and Bogdan S. Melnik
submission deadline 31 Jan 2027 | Viewed by 54 | Submission Open
Keywords: Mpemba effect; first-order phase transitions; water freezing; ice nucleation; supercooling; colloids; quantum Mpemba effects
(This special issue belongs to the Section Physical Chemistry)
Photothermal Materials for Drug Delivery
edited by
submission deadline 4 Feb 2027 | Viewed by 125 | Submission Open
Keywords: photothermal materials; drug delivery; disease therapy
(This special issue belongs to the Section Materials Chemistry)
Natural Antioxidants: Applications in Foods, Medicine and Cosmetics submission deadline 10 Feb 2027 | 2 articles | Viewed by 810 | Submission Open
Keywords: natural antioxidants; bioactive compounds; plant extracts; polyphenols; phytochemicals; antioxidant potential
(This special issue belongs to the Section Natural Products Chemistry)
Natural Compounds for Disease and Health, 4th Edition submission deadline 15 Feb 2027 | 3 articles | Viewed by 1852 | Submission Open
Keywords: natural products; phytochemistry; structure–activity relationship; mechanisms of action; anti-aging; cancer; cardiovascular diseases; digestive diseases; endocrine disorders; immune diseases; infections; inflammation; liver diseases; metabolic diseases; musculoskeletal diseases; neurodegenerative diseases; pain; psychiatric diseases; renal diseases; respiratory diseases
(This special issue belongs to the Section Natural Products Chemistry)
Valorization of Agri-Food By-Products for Disease Prevention: Extraction, Characterization and Translational Potential submission deadline 15 Feb 2027 | 1 articles | Viewed by 1760 | Submission Open
Keywords: agri-food by-products; bioactive compounds; health promotion; green extraction; circular bioeconomy
(This special issue belongs to the Section Food Chemistry)
Bioactive Natural Product Compounds in Cancer Prevention and Therapy submission deadline 15 Feb 2027 | 1 articles | Viewed by 1188 | Submission Open
Keywords: natural product; cytotoxic; bioactivity mechanism; cancer; drug discovery; drug delivery; chemoprevention
(This special issue belongs to the Section Natural Products Chemistry)
Recent Trends in Pharmaceutical Analysis for Drug Development, Therapeutic Monitoring and Biomarker Discovery submission deadline 15 Feb 2027 | Viewed by 549 | Submission Open
Keywords: pharmaceutical analysis; bioanalysis; drug development; therapeutic monitoring; biomarker discovery; omics; toxicological analysis
(This special issue belongs to the Section Medicinal Chemistry)
Enzyme Inhibitors: Structural Characterization and Applications submission deadline 15 Feb 2027 | Viewed by 173 | Submission Open
Keywords: enzyme inhibitors; DFT; molecular docking; molecular dynamics; structure–activity relationship
(This special issue belongs to the Section Medicinal Chemistry)
Natural Bioactives and Functional Ingredients in Foods
edited by
submission deadline 16 Feb 2027 | 8 articles | Viewed by 7116 | Submission Open
Keywords: natural bioactive compounds; functional food ingredients; health-promoting foods; nutraceuticals; food innovation
(This special issue belongs to the Section Food Chemistry)
Photoelectrochemical Properties of Nanostructured Thin Films
edited by , Zheng Xie and Xiaofeng Zhao
submission deadline 27 Feb 2027 | 3 articles | Viewed by 4251 | Submission Open
Keywords: photoelectrochemical water splitting; CO2 reduction; photocatalysis; surface engineering; co-catalyst integration; sustainable energy conversion; thin-film heterojunctions; advanced functional nanomaterials
(This special issue belongs to the Section Photochemistry)
Advances in Natural Products and Their Biological Activities—2nd Edition
edited by , , Roseli Barbosa and Francisco Assis Bezerra Da Cunha
submission deadline 28 Feb 2027 | 13 articles | Viewed by 19106 | Submission Open
Keywords: phytochemical; natural product; phytotherapy; medicinal plants; biological activity; pharmaceutical formulations; biological activity; pharmacological or toxicology effects
(This special issue belongs to the Section Natural Products Chemistry)
Antimicrobial Compounds and Biocontrol Strategies in Food Microbiology and Safety submission deadline 28 Feb 2027 | 5 articles | Viewed by 10684 | Submission Open
Keywords: antimicrobial compound; natural; synthetic; microbial; application; biocontrol; food; crop; agricultural; pathogenic; spoilage; bacteria; mold; in vitro; in vivo; mechanisms of action; membrane disruption; enzyme inhibition; interference with microbial communication; resistance management
(This special issue belongs to the Section Food Chemistry)
Recent Advances in Cannabis and Hemp Research—2nd Edition
edited by
submission deadline 28 Feb 2027 | 11 articles | Viewed by 10136 | Submission Open
Keywords: Cannabis sativa; hemp; cannabinoids; terpenes; phenolics; secondary metabolites; by-products; biological activity; protein; polysaccharide
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Heterocyclic Synthesis, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 8 articles | Viewed by 9469 | Submission Open
Keywords: heterocycles; stereoselective synthesis; sustainable synthesis; one-pot reactions; multicomponent reactions; catalysis
(This special issue belongs to the Section Organic Chemistry)
Biotechnology and Biomass Valorization
edited by , and Parushi Nargotra
submission deadline 28 Feb 2027 | 7 articles | Viewed by 9385 | Submission Open
Keywords: biomass; conversion; utilization; enzyme; biological; microorganism; fermentation; high value-added product; biofuel; biogas; bioplastic; biochemical material; functional ingredient; bio-based material; metabolic engineering; synthetic biology; biorefining; bioresource; food waste; agricultural by-product; marine biological resource; extraction; purification; life cycle assessment (LCA)
(This special issue belongs to the Section Green Chemistry)
Molecular Insights into Functional Lipids in Food Chemistry
edited by and Siyu Zhang
submission deadline 28 Feb 2027 | 6 articles | Viewed by 8636 | Submission Open
Keywords: structured lipid; synthesis; crystallization; fatty acid; glyceride
(This special issue belongs to the Section Food Chemistry)
Bioactive Compounds as Modulators of Antioxidant Activity and Inflammatory Processes in Related Diseases
edited by
submission deadline 28 Feb 2027 | 6 articles | Viewed by 6209 | Submission Open
Keywords: natural bioactive compounds; antioxidant activities; anti-inflammatory activities; efficacy, safety, concentration-dependent effects; antioxidant/pro-oxidant balance
(This special issue belongs to the Section Natural Products Chemistry)
Opportunities and Challenges in Organic Optoelectronic Materials submission deadline 28 Feb 2027 | 3 articles | Viewed by 6162 | Submission Open
Keywords: organic semiconductors; organic photonics; inorganic/organic hybrid materials; excitons; electroluminescence; photovoltaics; vacuum/solution process; energy transfer
(This special issue belongs to the Section Materials Chemistry)
Bioactivity of Natural Compounds: From Plants to Humans, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 5 articles | Viewed by 5435 | Submission Open
Keywords: natural compounds; blood vessel; endothelium dysfunction; advanced glycation end products (AGEs); reactive oxygen species (ROS); cytokines; ADMET properties; pharmacokinetics; gender difference
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis, Identification and Biological Evaluation of Novel Natural and Derivative Products
edited by
submission deadline 28 Feb 2027 | 2 articles | Viewed by 5355 | Submission Open
Keywords: organic synthesis; natural products; theoretical calculation; DFT; structure identification; biological evaluation
(This special issue belongs to the Section Natural Products Chemistry)
Heavy Metal Pollutants in Water, Wastewater and Sediments: From Occurrence and Determination to Removal and Recovery submission deadline 28 Feb 2027 | 5 articles | Viewed by 5121 | Submission Open
Keywords: heavy metals; analytical methods; wastewater; sludge; recycling; green chemistry; circular economy; sustainable development
(This special issue belongs to the Section Green Chemistry)
Advances in Dyes and Photochromics submission deadline 28 Feb 2027 | 4 articles | Viewed by 5026 | Submission Open
Keywords: photochromic compounds; green chemistry; molecular engineering; smart materials; environmental monitoring; electronic textiles; light-responsive materials; functional dyes; optical data storage; biomedical applications
(This special issue belongs to the Section Photochemistry)
Redox-Active Molecules as Key Players for Inflammatory Diseases
edited by Ange Mouithys-Mickalad
submission deadline 28 Feb 2027 | 3 articles | Viewed by 4807 | Submission Open
Keywords: redox-active Molecules; oxidative stress; inflammatory diseases; QSAR; computer-aided drug design; redox active natural compounds
(This special issue belongs to the Section Medicinal Chemistry)
Chitosan, Chitosan Derivatives, Polysaccharides and Their Applications—3rd Edition submission deadline 28 Feb 2027 | 6 articles | Viewed by 4598 | Submission Open
Keywords: chitin; chitosan; polysaccharide; polysaccharide-based systems
(This special issue belongs to the Section Macromolecular Chemistry)
Antimicrobial Peptide Assemblies
edited by
submission deadline 28 Feb 2027 | 2 articles | Viewed by 4487 | Submission Open
Keywords: peptides; peptide hybrids; peptide conjugates; self-assembly; stimuli-responsiveness; antimicrobial activity
(This special issue belongs to the Section Chemical Biology)
Natural Products and Microbiology in Human Health, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 5 articles | Viewed by 4065 | Submission Open
Keywords: traditional medicine; antibiotics; antibiotic natural products; probiotics; novel antimicrobial therapies; microbial toxins; phytochemicals; antibiotic-resistant bacteria; drug potentiation
(This special issue belongs to the Section Natural Products Chemistry)
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