Ionic Liquids and Deep Eutectic Solvents for Pharmaceutical Analysis
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 56
Editors
Interests: ionic liquids; deep eutectic solvents; thermal analysis; molecular interactions; physicochemical properties; differential scanning calorimetry; synthesis
Interests: green extraction; deep eutectic solvents; phytochemicals; antioxidant activity; chromatographic analysis; natural product chemistry; pharmaceutical analysis; herbal medicine
Special Issue Information
Dear Colleagues,
Deep eutectic solvents (DESs) and ionic liquids (ILs) have gained considerable attention in recent years due to their potential as environmentally friendly alternatives to conventional volatile organic solvents. Their molecular diversity, arising from the vast design space of ions, hydrogen bond donors, and acceptors, enables precise control over structure–property relationships that is unattainable in conventional molecular solvents. Their biocompatibility, biodegradability, and functional tunability make DES and ILs attractive for critical pharmaceutical challenges, including low solubility, polymorphism, and the bioavailability of drugs. In addition, particular attention will be given to the application of these solvent systems in the extraction, isolation, and analytical profiling of bioactive compounds from natural sources. The integration of deep eutectic solvents and ionic liquids with modern chromatographic and spectroscopic techniques represents a promising approach for improving the efficiency, selectivity, and sustainability of pharmaceutical analysis. Special emphasis will be placed on studies addressing the recovery and characterization of phytochemicals, antioxidant activity, and the development of green extraction methodologies aligned with current environmental and regulatory demands. The main objective of this Special Issue of Molecules is to publish original research articles and reviews that focus on the current status and future trends in the field of these solvents (DES and ILs) in the area of pharmaceutical analysis. We invite submissions that explore various aspects, including the design, novel synthetic strategies, characterization, investigation of their fundamental physical and chemical properties, mechanistic insights of deep eutectic solvents and/or ionic liquids, as well as their potential and emerging applications in field of industry such as pharmaceuticals and pharmaceutical analysis.
This Special Issue also aims to highlight interdisciplinary approaches that combine green chemistry principles with advanced analytical techniques, contributing to the development of innovative and sustainable solutions in pharmaceutical and natural product research.
Dr. Snežana M. Papović
Dr. Branislava Teofilović
Guest Editors
Manuscript Submission Information
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Keywords
- ionic liquids
- deep eutectic solvents
- physicochemical analysis
- green extraction and separation
- phytochemicals
- pharmaceutical analysis
- chromatographic analysis
- active pharmaceutical ingredients
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