Capsaicin

Dear Colleagues,

Capsaicin has been long considered as a chemopreventive agent that exhibits anti-growth activity against various lines of cancer cell lines, often associated with its apoptotic activity. However, numerous reports have demonstrated that capsaicin possesses paradoxical effects on cell growth and is differentially cytotoxic toward cancer cells and non-cancerous cells. The specific target(s) of capsaicin and the resulting mechanisms underlying this difference are not yet fully understood, and remain to be discovered.

This Special Issue is devoted to recent developments in this very important and emerging area of research. The scope is broad, including but not limited to effect of capsaicin on cellular-signaling events in the functioning, growth and differentiation of cells in normal and pathological states, effect of capsaicin on the regulation of protein expression in different states, the effect of capsaicin on gene expression, bioinformatic studies related to the mechanisms of signaling events and gene regulation, and studies of capsaicin agonists and antagonists.

Prof. Dr. Pin Ju Chueh
Guest Editor

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