Special Issue "Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (30 April 2013) | Viewed by 56185
Interests: drug allergy; autoimmune diseases; arginine metabolism; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue in Molecules: Anti-inflammatory and Anti-allergy Agents in Medicinal Chemistry-III
Special Issue in Antioxidants: Oxidative Stress in Autoimmune Diseases
Although anti-inflammatory agents are extensively prescribed across all age groups worldwide there are several unanswered questions about their exact mechanism of action and their potential renal and cardiovascular toxicity. These issues are largely related to 1) the validity of available methods for assessing selectivity towards the cyclooxygenase enzyme isoforms COX-1 and COX-2; 2) the exact role played by COX-1 and COX-2 in renal and vascular homeostasis in animal models and humans; and 3) the interpretation of data from pharmacoepidemiological studies and meta-analyses.
This special issue of Molecules welcomes previously unpublished manuscripts covering all aspects of pharmacology and chemistry of anti-inflammatory drugs, in particular the development of novel anti-inflammatory drugs and methods for assessing COX selectivity, pharmacodynamic effects of novel and existing anti-inflammatory drugs in animal models and humans, and the expression and role of different COX isoforms in the kidney and vasculature.
Prof. Dr. Arduino A Mangoni
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- organic chemistry
- drug development
- enzyme kinetics
- enzyme expression
- renal toxicity
- cardiovascular toxicity
- medicinal chemistry