Virulence-Associated Genes, Pathogenesis, and Immune Evasion Mechanisms of Swine Viruses

Dear Colleagues,

Swine viruses continue to pose significant threats to global animal health, food security, and agricultural economies. Understanding the molecular determinants that govern viral virulence, host–pathogen interactions, and immune evasion is essential for the development of effective vaccines and antiviral strategies.

This Special Issue of Microorganisms aims to provide a platform for advancing knowledge on virulence-associated genes and their roles in the pathogenesis of major swine viruses, including, but not limited to, African swine fever virus (ASFV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus (PCV), Rotavirus (RV), and swine influenza virus (SIV). We particularly welcome studies that elucidate viral genetic factors influencing replication, transmission, and tissue tropism, as well as host immune responses and viral countermeasures.

We also encourage the application of cutting-edge technologies such as reverse genetics, multi-omics approaches, and advanced in vitro and in vivo models to dissect viral pathogenesis and host responses.

This Special Issue aims to provide a comprehensive and timely resource to bridge critical knowledge gaps and support the development of next-generation vaccines and antiviral interventions for the control of economically important swine viral diseases.

Dr. Lihua Wang
Guest Editor

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