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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Coronary Artery Disease from Acute Manifestation to Long Term Consequences

edited by

Elena Emilia Babeş

submission deadline 30 Dec 2026 | 6 articles | Viewed by 10760 | Submission Open

Keywords: coronary artery disease; acute coronary syndrome; coronary revascularization; coronary angiography; CT angiography; antiplatelet therapy; inflammation

(This special issue belongs to the Section Cardiology)

Emerging Biomarkers in Parkinsonian Syndromes and Dementias: From Diagnosis to Therapeutic Targets

edited by

Anastasia Bougea

submission deadline 30 Dec 2026 | Viewed by 176 | Submission Open

Keywords: Parkinsonian syndromes; dementias; biomarkers

(This special issue belongs to the Section Neurology)

Update on Obstetric Anaesthesia and Perinatology

edited by Tatjana Stopar-Pintarič and

Miha Lučovnik

submission deadline 30 Dec 2026 | Viewed by 105 | Submission Open

Keywords: obstetric anaesthesia; perinatology; labour analgesia; epidural analgesia; remifentanil patient-controlled analgesia; maternal obesity; high-risk pregnancy; maternal comorbidities; hypertensive disorders of pregnancy; obstetric haemorrhage

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Drug-Induced Anaphylaxis: Advances in Diagnosis, Biomarkers and Rapid Drug Desensitization

edited by Ticha Rerkpattanapipat

submission deadline 30 Dec 2026 | Viewed by 102 | Submission Open

Keywords: drug-induced anaphylaxis; drug hypersensitivity reactions; biomarkers; in vitro test; drug provocation test; drug desensitization; biologics and chemotherapy hypersensitivity

(This special issue belongs to the Section Hematology and Immunology)

Spinal Surgery: Advances and Concerns

edited by Filippo Migliorini and Gaetano Pappalardo

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2569 | Submission Open

Keywords: spine; surgery; minimally invasive; deformity; motion preservation; oncology; infections; trauma; complications; instrumentation; outcomes

(This special issue belongs to the Section Neurology)

Implementing Technological Advances in Psychiatry: Challenges and Opportunities

edited by

Mirko Manchia

and Alessio Squassina

submission deadline 31 Dec 2026 | 1 articles | Viewed by 978 | Submission Open

Keywords: precision psychiatry; machine learning; risk stratification; pharmagenomics; AUC; black box; genomics; epigenetics

(This special issue belongs to the Section Psychiatry)

Osteoarthritis: Innovations in Joint Preservation and Replacement

edited by

Hassan Zmerly

Massimiliano Mosca

and

Silvio Caravelli

submission deadline 31 Dec 2026 | Viewed by 356 | Submission Open

Keywords: osteoarthritis; cartilage; arthroscopy; joint replacement; knee arthroplasty; hip arthroplasty; ankle arthroplasty; robotic

(This special issue belongs to the Section Orthopedics)

Latest Advances of Colorectal Surgery

edited by

Dragoş Eugen Georgescu

submission deadline 31 Dec 2026 | Viewed by 347 | Submission Open

Keywords: minimally invasive surgery; colorectal cancer; surgical outcomes; enhanced recovery after surgery; perioperative management

(This special issue belongs to the Section Gastroenterology & Hepatology)

Structural Heart Interventions and Interventional Imaging: Current Advances and Future Directions

edited by

Kasparas Briedis

and Jorge Sanz-Sánchez

submission deadline 31 Dec 2026 | Viewed by 315 | Submission Open

Keywords: structural heart disease; transcatheter interventions; interventional cardiology; multimodality imaging; TAVI; transcatheter mitral and tricuspid interventions

(This special issue belongs to the Section Cardiology)

Recent Advances in Pulmonary Hypertension: Diagnosis and Treatment

edited by Yuri Matusov and Suhail Dohad

submission deadline 31 Dec 2026 | Viewed by 174 | Submission Open

Keywords: pulmonary hypertension; PH-ILD; interstitial lung disease; right ventricular failure; PH-COPD; HFpEF-PH

(This special issue belongs to the Section Pulmonology)

Fundamental Principles and Contemporary Advances in Orthopaedics and Trauma Surgery

edited by Christoph Linhart and Daniel Pfeufer

submission deadline 31 Dec 2026 | Viewed by 169 | Submission Open

Keywords: orthopaedics surgery; traumatology; functional treatment; bone quality assessment; osteoporosis; pelvic insufficiency fractures; orthogeriatric; periprosthetic fracture; osteosynthesis; nonunion; fracture healing; pseudarthrosis; delayed fracture

(This special issue belongs to the Section Orthopedics)

Advancing Precision in Breast Cancer Regional Nodal Irradiation

edited by

Seung-Gu Yeo

submission deadline 31 Dec 2026 | Viewed by 129 | Submission Open

Keywords: breast cancer; radiation therapy; regional nodal irradiation; lymphedema; incidental irradiation; axillary lateral vessel thoracic junction; target volume

(This special issue belongs to the Section Oncology)

Advances in Neurodegenerative Diseases: From Molecular Mechanisms to Therapeutic Strategies

edited by

Sujung Yeo

submission deadline 31 Dec 2026 | Viewed by 119 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer's disease; Parkinson's disease; neurodegeneration; protein aggregation; neuroinflammation; neuroprotection; biomarkers; therapeutic targets

(This special issue belongs to the Section Neurology)

Advances in the Field of Neurology: Innovations in Research and Treatment

edited by

Alberto Ouro

and

Allison B. Reiss

submission deadline 10 Jan 2027 | 5 articles | Viewed by 8823 | Submission Open

Keywords: neuron; synapse; neuroinflammation; motor neuron diseases; neurodegeneration; myelin; seizures

(This special issue belongs to the Section Neurology)

Coping Strategies Across the Lifespan: Psychological and Neuropsychological Perspectives

edited by

Argyroula Kalaitzaki

Maria Theodoratou

and Panoraia Andriopoulou

submission deadline 10 Jan 2027 | 1 articles | Viewed by 1926 | Submission Open

Keywords: coping; clinical psychology; neuropsychology; resilience; brain plasticity; adaptation; quality of life; cognitive function; emotional regulation; stress adaptation; lifespan

(This special issue belongs to the Section Psychiatry)

Innovations and Challenges in Thoracic Surgery: Present and Future Directions

edited by Servet Bölükbas and Konstantinos Grapatsas

submission deadline 10 Jan 2027 | 1 articles | Viewed by 1345 | Submission Open

Keywords: thoracic surgery; lung cancer; pulmonary metastasectomy; mesothelioma; lung volume reduction surgery; minimally invasive surgery (VATS/ RATS); enhanced recovery after surgery (ERAS) protocols; multidisciplinary care; surgical oncology; postoperative outcomes

(This special issue belongs to the Section Surgery)

Real-World Implementation of CBT for OCD: Access, Adaptation, and Digital Innovations Across Care Settings

edited by

Keiichiro Mukai

and Bethany May Wootton

submission deadline 10 Jan 2027 | Viewed by 517 | Submission Open

Keywords: obsessive–compulsive disorder (OCD); cognitive behavioral therapy (CBT); implementation; real-world effectiveness; digital CBT; Internet-based CBT (iCBT); app-based interventions; blended care; stepped care; low-intensity CBT; high-intensity CBT; access to care; health systems

(This special issue belongs to the Section Psychiatry)

Ulcerative Colitis: Pathogenesis, Clinical Management, and Emerging Therapies

edited by Olga Giouleme and

Alexandra Menni

submission deadline 10 Jan 2027 | Viewed by 355 | Submission Open

Keywords: ulcerative colitis; biological therapies; microbiome; innovative techniques; drug monitoring; prognostic tools; diagnosis and treatment algorithm

(This special issue belongs to the Section Gastroenterology & Hepatology)

Diagnostic Approaches and Therapies of Periodontitis

edited by Aureliana Caraiane and Doriana Agop-Forna

submission deadline 10 Jan 2027 | Viewed by 108 | Submission Open

Keywords: periodontitis; oral health-related quality of life; peri-prosthetic tissues; periodontal–prosthetic interface; treatment planning; regenerative periodontal therapy

(This special issue belongs to the Section Dentistry and Oral Health)

Opportunities and Challenges in Brain and Spine Tumor Treatment in the Era of Artificial Intelligence and Precision Medicine

edited by

Mirza Pojskić

and

Benjamin Saß

submission deadline 10 Jan 2027 | Viewed by 90 | Submission Open

Keywords: neuro-oncology; brain tumors; spinal tumors; artificial intelligence; precision medicine; neuro-navigation; augmented reality; robotics in neurosurgery; navigated 3D ultrasound; radiomics; computational neurosurgery; fluorescence-guided surgery

(This special issue belongs to the Section Neurology)

Surgical Advances in Genitourinary Reconstruction

edited by

Miroslav L. Djordjevic

, Marta Bizic and Borko Stojanovic

submission deadline 10 Jan 2027 | Viewed by 69 | Submission Open

Keywords: genitalia; congenital anomalies; surgery; reconstruction; transgender

(This special issue belongs to the Section Urology & Nephrology)

Advances and Perspectives in Esophageal Cancer Treatment

edited by Koji Otsuka and

Florin Achim

submission deadline 15 Jan 2027 | 2 articles | Viewed by 9766 | Submission Open

Keywords: minimally invasive esophagectomy; robotic esophagectomy; locally advanced esophageal cancer; immunotherapy for esophageal cancer; cervical esophageal cancer; multidisciplinary approach to esophageal cancer

(This special issue belongs to the Section Surgery)

New Insights into Heart Failure Management and Treatment

edited by

Alejandro N. Barbagelata

and Edgardo J. Kaplinsky

submission deadline 15 Jan 2027 | 3 articles | Viewed by 3384 | Submission Open

Keywords: heart failure; cardiovascular disease; treatment advances; management strategies; personalized medicine; clinical guidelines; diagnostic innovations; multidisciplinary care; emerging therapies; patient outcomes

(This special issue belongs to the Section Cardiology)

Advances in Dental Prosthetics

edited by

Zoltán Géczi

and

Dániel Végh

submission deadline 15 Jan 2027 | 1 articles | Viewed by 1799 | Submission Open

Keywords: dental prosthetics; CAD/CAM; 3D printing; implant-supported restorations; prosthodontics; digital dentistry; patient-centered outcomes

(This special issue belongs to the Section Dentistry and Oral Health)

Prenatal Diagnosis: Current Challenges and Future Perspectives

edited by Yaron Zalel, Kristiina Rull and

Natalija Vedmedovska

submission deadline 15 Jan 2027 | 1 articles | Viewed by 1134 | Submission Open

Keywords: prenatal diagnosis; non-invasive prenatal testing; fetal imaging; genomic medicine; multiomics; artificial intelligence in prenatal care; maternal–fetal health

(This special issue belongs to the Section Obstetrics and Gynecology)

Physiotherapy in Musculoskeletal Disorders: Assessment, Intervention, and Outcomes

edited by

Rubén Cuesta-Barriuso

and

Roberto Ucero-Lozano

submission deadline 15 Jan 2027 | Viewed by 552 | Submission Open

Keywords: physiotherapy; musculoskeletal disorders; diagnostic; treatment; prevention; multidisciplinary approach; physical therapy modalities

(This special issue belongs to the Section Orthopedics)

Advances in Oral Diseases and Oral Implantology

edited by

Andrei Paul Tent

and

Alexandru Mester

submission deadline 15 Jan 2027 | 1 articles | Viewed by 490 | Submission Open

Keywords: dental implants; oral diseases; peri-implantitis; osseointegration; regenerative dental surgery; digital implantology; oral rehabilitation; personalized implants

(This special issue belongs to the Section Dentistry and Oral Health)

Real-World Evidence in Severe Asthma: Outcomes, Adherence, and Unmet Needs

edited by

Ludovica Capitelli

submission deadline 15 Jan 2027 | Viewed by 121 | Submission Open

Keywords: severe asthma; real-world evidence; biologics; unmet clinical needs; precision therapy

(This special issue belongs to the Section Pulmonology)

Cardiovascular Diseases and Type 2 Diabetes: 3rd Edition

edited by

Cristina Tudoran

submission deadline 15 Jan 2027 | Viewed by 95 | Submission Open

Keywords: acute and chronic coronary syndrome; endothelial dysfunction; arterial hypertension; heart failure; insulin resistance; diabetes mellitus type 2

(This special issue belongs to the Section Endocrinology)

ACL: From Injury to Return to Sport

edited by

Marko Stojanović

submission deadline 19 Jan 2027 | 3 articles | Viewed by 3905 | Submission Open

Keywords: ACL; rehabilitation; neuromuscular training; return to sport; surgical techniques

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Recent Advances in Cardiovascular Surgery

edited by Massimo Baudo and

Lorenzo Di Bacco

submission deadline 20 Jan 2027 | 4 articles | Viewed by 5617 | Submission Open

Keywords: cardiac surgery; surgical outcomes; heart valves; cabg; left atrial appendage; aortic diseases; heart failure; new technologies

(This special issue belongs to the Section Cardiology)

Systematic Reviews and Outcomes Research in Emergency Medicine

edited by

Ovidiu Alexandru Mederle

submission deadline 20 Jan 2027 | 3 articles | Viewed by 2785 | Submission Open

Keywords: emergency department; critical illness; risk stratification; quality of care; patient outcomes; evidence-based practice; clinical decision-making; resuscitation; telemedicine in emergency care; emergency medical services

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advances in Reconstructive and Plastic Surgery

edited by Tien-Hsiang Wang, Wen‐Kuan Chiu and

Dun-Hao Chang

submission deadline 20 Jan 2027 | 3 articles | Viewed by 2465 | Submission Open

Keywords: reconstructive surgery; plastic surgery; microsurgery; tissue engineering; regenerative medicine; wound healing; flap surgery; 3D surgical planning; limb salvage; craniofacial reconstruction; breast reconstruction; surgical innovation

(This special issue belongs to the Section Surgery)

Spinal Tumors: 2nd Edition

edited by

Michael Schwake

and

Ehab Shiban

submission deadline 20 Jan 2027 | 1 articles | Viewed by 766 | Submission Open

Keywords: spinal tumors; spinal metastases; spine surgery; intraoperative monitoring; quality of life; patient outcomes; postoperative care; functional recovery; survival; spine oncology

(This special issue belongs to the Section Neurology)

New Trends in Interventional Cardiology

edited by

Nikolaos Ktenopoulos

submission deadline 20 Jan 2027 | 1 articles | Viewed by 403 | Submission Open

Keywords: interventional cardiology; percutaneous coronary intervention; coronary artery disease; structural heart disease; transcatheter aortic valve implantation; mitral valve intervention; tricuspid valve intervention; intracoronary imaging; chronic total occlusion; artificial intelligence

(This special issue belongs to the Section Cardiology)

Perioperative and Intensive Care Challenges in Cardiac Surgery

edited by

Judita Andrejaitienė

and Povilas Jakusǩa

submission deadline 20 Jan 2027 | 1 articles | Viewed by 363 | Submission Open

Keywords: cardiac surgery; cardiothoracic anesthesia; perioperative medicine; intensive care; cardiothoracic critical care; postoperative complications; hemodynamic monitoring; mechanical circulatory support; extracorporeal membrane oxygenation; postoperative delirium; respiratory failure; vasoplegic syndrome; right ventricular dysfunction; organ protection; enhanced recovery after surgery; perioperative monitoring; postoperative critical care; extracorporeal circulation; patient safety; multidisciplinary care

(This special issue belongs to the Section Cardiology)

Epidemiology, Differential Diagnosis and Management of Hair Loss Disorders

edited by

Aditya K. Gupta

submission deadline 20 Jan 2027 | Viewed by 89 | Submission Open

Keywords: hair loss disorders; alopecia; epidemiology; differential diagnosis; scarring alopecia; non-scarring alopecia; hair loss management

(This special issue belongs to the Section Dermatology)

Emerging Trends in Infectious Disease Prevention and Control

edited by

Iulia-Cristina Bagiu

and

Florin George Horhat

submission deadline 25 Jan 2027 | 9 articles | Viewed by 12488 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; novel identification; molecular diagnosis; vaccines; artificial intelligence; epidemiology; healthcare policies; alternative therapy

(This special issue belongs to the Section Infectious Disease)

New Advances in Inflammatory Bowel Disease and Diarrheal Disorders

edited by

Ion Rogoveanu

and

Sergiu Marian Cazacu

submission deadline 25 Jan 2027 | 6 articles | Viewed by 6417 | Submission Open

Keywords: ulcerative colitis; Crohn’s disease; Clostridium difficile; celiac disease; cytomegalovirus colitis; Yersinia colitis; intestinal tuberculosis; villous atrophy

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advances in Use of PET-CT Imaging in Disease Diagnosis

edited by Ana María García-Vicente and

Edel Noriega-Álvarez

submission deadline 25 Jan 2027 | 1 articles | Viewed by 2695 | Submission Open

Keywords: PET-CT; molecular imaging; diagnostic imaging; radiotracers; oncology; inflammation and infection; neurology; cardiovascular imaging; artificial intelligence in imaging; precision medicine

Prosthodontics and Restorative Dentistry: New Insights and Future Directions

edited by Edoardo Mancuso and

Mariangela Cernera

submission deadline 25 Jan 2027 | 2 articles | Viewed by 2613 | Submission Open

Keywords: prosthodontics; restorative dentistry; digital dentistry; CAD/CAM and 3D Printing; adhesive dentistry; esthetics and function; personalized dentistry

(This special issue belongs to the Section Dentistry and Oral Health)

Osteoporosis: Advances in Diagnosis, Risk Assessment, Surgical Treatment, and Regenerative Therapies

edited by Yusuke Oshita and Takayuki Imura

submission deadline 25 Jan 2027 | 3 articles | Viewed by 1902 | Submission Open

Keywords: osteoporosis; fragility fracture; bone mineral density (BMD)

(This special issue belongs to the Section Orthopedics)

Advances in Vascular Surgery: Evolving Frontiers in Arterial, Venous, and Aneurysmal Disease Management

edited by Theofanis Papas, Paraskevi Tsiantoula and

Konstantinos Roditis

submission deadline 25 Jan 2027 | 2 articles | Viewed by 1065 | Submission Open

Keywords: vascular surgery; endovascular interventions; abdominal aortic aneurysm; fenestrated EVAR; branched EVAR; thoracoabdominal endografts; venous disease; deep venous thrombosis; catheter-directed thrombolysis; mechanical thrombectomy

(This special issue belongs to the Section Surgery)

Recent Advances in Hard-to-Heal Wound Management

edited by Miki Fujii and Hajime Matsumura

submission deadline 25 Jan 2027 | Viewed by 202 | Submission Open

Keywords: hard-to-heal wounds; chronic wounds; diabetic foot ulcers; advanced wound care; limb salvage; biofilm; negative pressure wound therapy

Anesthesia and Analgesia in Surgery

edited by

Chun-Yu Chang

submission deadline 25 Jan 2027 | Viewed by 82 | Submission Open

Keywords: Analgesia; anesthesia; enhanced recovery after surgery; multimodal analgesia; opioid-sparing analgesia; patient safety; perioperative care; postoperative pain; regional anesthesia

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Updates on the Changing Landscape of Immunotherapy and Targeted Therapy in Cancer

edited by

Monica Neagu

and

Gheorghita Isvoranu

submission deadline 29 Jan 2027 | 4 articles | Viewed by 8567 | Submission Open

Keywords: cancer immunotherapy; cancer targeted therapy; immune checkpoint targeted therapy; cell therapy in cancer; signal transduction inhibitors; small molecules of cancer drugs; tumor microenvironment; efficacy biomarkers for cancer therapy; mechanisms of resistance

(This special issue belongs to the Section Oncology)

Advanced Clinical Approaches in Perioperative Pain Management

edited by

Mark Ulrich Gerbershagen

submission deadline 30 Jan 2027 | 4 articles | Viewed by 6686 | Submission Open

Keywords: anesthesiology; regional anesthesia; acute pain; chronic pain; perioperative pain management

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Liver Surgery: Current Treatment and Future Options

edited by

Suk-Won Suh

submission deadline 31 Jan 2027 | 1 articles | Viewed by 3328 | Submission Open

Keywords: liver surgery; hepatic resection; liver transplantation; hepatocellular carcinoma; liver cirrhosis; liver failure; liver metastasis; cholangiocarcinoma

(This special issue belongs to the Section Gastroenterology & Hepatology)

Artificial Intelligence: A Possible 'Game Changer' in the Fight Against Cancer

edited by

Konstantinos Dimas

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2925 | Submission Open

Keywords: artificial intelligence; cancer biology; drug discovery and repurposing; diagnosis and detection; treatment optimization; clinical practice and patient support

(This special issue belongs to the Section Oncology)

Gut Microbiota and Chronic Diseases: From Pathophysiology to Clinical Implication

edited by

Ludovico Abenavoli

and

Ghizlane Bendriss

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1374 | Submission Open

Keywords: gut microbiota; dysbiosis; chronic diseases; host-microbiota interaction; multi-omics; inflammation; immune response; biomarkers; diagnosis; precision medicine; therapeutic strategies

(This special issue belongs to the Section Gastroenterology & Hepatology)

Displaying special issue 251-300 on page 6 of 8.

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