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Recent Advances in Hard-to-Heal Wound Management

A Special Issue of Medicina (ISSN 1648-9144).

Deadline for manuscript submissions: 25 January 2027 | Viewed by 273

Editors


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Guest Editor
Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, Japan
Interests: wound healing; extracellular matrix; small intestinal submucosa; dynamic reciprocity; M2-macrophage; matrix metallic proteinases; matrix-bound vesicle

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Guest Editor
Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, Japan
Interests: burns; acute and chronic wounds; regenrative medicine; tissue engineering; wound healing
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Special Issue Information

Dear Colleagues,

Chronic wounds represent a major global health challenge associated with impaired physical function, reduced quality of life and substantial healthcare costs. As populations age and the prevalence of diabetes, chronic venous insufficiency and peripheral arterial disease increases, the incidence of chronic wounds continues to rise worldwide.

Although the principles of chronic wound management have become increasingly standardized, many patients still suffer from prolonged non-healing wounds, often referred to as hard-to-heal wounds. These wounds remain difficult to manage because of complex underlying factors such as ischemia, infection, biofilm formation, systemic comorbidities and impaired tissue regeneration.

This Special Issue aims to highlight recent advances in the multidisciplinary management of hard-to-heal wounds, including diabetic foot ulcers, venous leg ulcers, pressure injuries and ischemic ulcers.

We warmly invite colleagues from around the world to submit original research articles, reviews and systematic reviews describing innovative approaches and clinical experiences in the management of hard-to-heal wounds, with the goal of improving patient outcomes and advancing the field of wound care.

Dr. Miki Fujii
Prof. Dr. Hajime Matsumura
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hard-to-heal wounds
  • chronic wounds
  • diabetic foot ulcers
  • advanced wound care
  • limb salvage
  • biofilm
  • negative pressure wound therapy

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Published Papers

This special issue is now open for submission.
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