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New Trends in Interventional Cardiology

A Special Issue of Medicina (ISSN 1648-9144) belonging to the section "Cardiology".

Deadline for manuscript submissions: 20 January 2027 | Viewed by 1258

Editor


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Guest Editor
First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, 11527 Athens, Greece
Interests: interventional cardiology; coronary artery disease; structural heart disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Interventional cardiology is undergoing a period of unprecedented innovation, driven by advances in device technology, intracoronary imaging, physiology-guided interventions, structural heart disease therapies and the integration of digital health and artificial intelligence into clinical practice. As cardiovascular disease remains the leading cause of morbidity and mortality worldwide, there is an urgent need to optimize patient selection, procedural outcomes and long-term management through evidence-based and technologically advanced approaches.

Over the past decade, significant progress has been achieved in the treatment of coronary artery disease, valvular heart disease, heart failure and complex cardiovascular conditions. Contemporary interventional strategies increasingly incorporate precision medicine principles, multimodality imaging, computational modeling and minimally invasive techniques. At the same time, challenges persist regarding procedural complexity, patient-specific risk stratification, access to novel therapies and the translation of emerging evidence into routine clinical practice. These developments create exciting opportunities for researchers and clinicians to redefine standards of care and improve cardiovascular outcomes globally.

This Special Issue aims to present and disseminate the most recent advances related to interventional cardiology, encompassing both established and emerging therapeutic approaches. We welcome original research articles, systematic reviews, meta-analyses, clinical studies, translational research and expert perspectives addressing innovations in coronary, structural and peripheral cardiovascular interventions, as well as technologies that support decision-making and procedural success.

Topics of interest for publication include, but are not limited to, the following:

  • Coronary artery disease and contemporary percutaneous coronary intervention (PCI) treatment;
  • Complex and high-risk coronary interventions;
  • Intracoronary imaging (IVUS, OCT) and physiology-guided revascularization;
  • Chronic total occlusion interventions;
  • Structural heart disease interventions, including transcatheter aortic, mitral and tricuspid valve therapies;
  • Left atrial appendage closure and transcatheter management of congenital heart diseases;
  • Mechanical circulatory support and cardiogenic shock interventions;
  • Peripheral and endovascular interventions;
  • Artificial intelligence, machine learning and computational modeling in interventional cardiology;
  • Digital health, telemedicine and remote patient monitoring;
  • Precision medicine and personalized interventional strategies;
  • Clinical outcomes, registries and real-world evidence in interventional practice;
  • Future directions and emerging concepts in cardiovascular interventions.

We look forward to receiving high-quality contributions that advance scientific knowledge and foster innovation in this rapidly evolving field.

Dr. Nikolaos Ktenopoulos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • interventional cardiology
  • percutaneous coronary intervention
  • coronary artery disease
  • structural heart disease
  • transcatheter aortic valve implantation
  • mitral valve intervention
  • tricuspid valve intervention
  • intracoronary imaging
  • chronic total occlusion
  • artificial intelligence

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Published Papers (1 paper)

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Review

25 pages, 443 KB  
Review
Acute Coronary Syndrome and Recreational Drug Use: A Comprehensive Review
by Panagiotis Iliakis, Konstantina Ntalekou, Eleftheria Stamou, Aikaterini-Eleftheria Karanikola, Andreas Mavroudis, Nikolaos Ktenopoulos, Paschalis Karakasis, Panagiotis Theofilis, Obayda Azizy, Anna Pitsillidi, Aikaterini Damianaki, Eirini Beneki, Alexandros Kasiakogias, Christina Chrysohoou, Polykarpos Christos Patsalis, Kyriakos Dimitriadis and Konstantinos Tsioufis
Medicina 2026, 62(8), 1477; https://doi.org/10.3390/medicina62081477 - 30 Jul 2026
Viewed by 988
Abstract
Acute coronary syndrome (ACS) remains a leading cause of cardiovascular morbidity and mortality worldwide. Although traditional cardiovascular risk factors remain central to ACS development, recreational drug use is increasingly recognized as a clinically relevant trigger, particularly in younger patients with fewer conventional risk [...] Read more.
Acute coronary syndrome (ACS) remains a leading cause of cardiovascular morbidity and mortality worldwide. Although traditional cardiovascular risk factors remain central to ACS development, recreational drug use is increasingly recognized as a clinically relevant trigger, particularly in younger patients with fewer conventional risk factors. This narrative review synthesized evidence identified through searches of PubMed/MEDLINE and Scopus up to June 2026, including clinical guidelines, systematic reviews, observational studies, mechanistic investigations, and clinically informative case-based evidence. Cannabis, cocaine, amphetamines, methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA), opioids, lysergic acid diethylamide (LSD), synthetic cannabinoids, and polysubstance use may promote myocardial ischemia and infarction through overlapping mechanisms, including sympathetic activation, coronary vasospasm, endothelial dysfunction, oxidative stress, inflammation, platelet activation, thrombosis, arrhythmogenesis, and myocardial oxygen supply–demand mismatch. Clinical presentation may be typical or atypical and may overlap with intoxication, withdrawal, anxiety, neurological symptoms, or non-cardiac chest pain, making diagnosis challenging. Underreporting of recreational drug use is common, and targeted toxicology screening may improve diagnostic accuracy and risk stratification, particularly in patients younger than 50 years, those with few traditional cardiovascular risk factors, or those presenting with otherwise unexplained ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), coronary vasospasm, arrhythmias, or cardiac arrest. Acute management should generally follow standard ACS guidelines, while considering drug-specific issues such as stimulant-induced vasospasm, sympathetic excess, cautious use of beta-blockers during acute intoxication, and preference for primary percutaneous coronary intervention when fibrinolysis carries increased risk. Long-term care should combine evidence-based secondary prevention with substance-use counseling, addiction medicine referral, cardiac rehabilitation, and behavioural interventions. This review summarizes the pathophysiology, clinical manifestations, epidemiology, treatment considerations, preventive strategies, and knowledge gaps related to recreational drug-associated ACS. Full article
(This article belongs to the Special Issue New Trends in Interventional Cardiology)
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