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Marine Drugs publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioactive Compounds from Challenging Marine Environments

edited by Seulah Lee

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3864 | Submission Open

Keywords: natural products; extreme marine ecosystems; novel bioactive compounds; marine chemical diversity; structural elucidation

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Bio-Active Components from Marine Sponge

edited by

Sylvain Petek

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3471 | Submission Open

Keywords: sponges; isolation; synthesis; bioactivity; anti-cancer; anti-infective; human health; animal health; eco-friendly solution; chemical ecology

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine Omics for Drug Discovery and Development, 2nd Edition

edited by

Min Zhao

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3004 | Submission Open

Keywords: marine genome; omics technology; marine natural products; marine drug discovery; high-throughput screening; computer-aided drug discovery/design; anti-disease; anti-cancer; anti-infectious; anti-inflammation; biological products; pharmacology; clinical outcome; AI-based drug discovery

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Bioactive Compound Discovery Through OSMAC Approach—2nd Edition

edited by

Xiaoling Lu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2210 | Submission Open

Keywords: marine microorganisms; secondary metabolites; OSMAC; epigenetic; cryptic; bioactivity

(This special issue belongs to the Section Marine Pharmacology)

Marine-Derived Polymers for Tissue Engineering and Drug Delivery Applications

edited by

Zulema Vargas

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2082 | Submission Open

Keywords: marine polysaccharides; marine proteins and peptides; tissue engineering; drug delivery; biomedical applications; marine-derived polymeric materials: manufacturing techniques for processing: 3D printing; freeze-drying; electrospinning; coating techniques; etc.; functionalization incorporation of new functional groups; composites and hybrid materials (organic/inorganic moieties); design strategies: porous platforms; scaffolds; fibers; capsules; nanoparticles; films; coatings; etc.

(This special issue belongs to the Section Biomaterials of Marine Origin)

Algae-Powered Skincare: Innovations in Marine-Derived Cosmeceuticals

edited by

Gonçalo Pereira da Rosa

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1511 | Submission Open

Keywords: marine macroalgae; cosmeceuticals; bioactive compounds; skincare; anti-aging; antioxidants; hyperpigmentation; UV protection; sustainable extraction; dermatological applications

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Diversity of Marine Fungi as a Source of Bioactive Natural Products, 3rd Edition

edited by

Dehai Li

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1330 | Submission Open

Keywords: marine fungus; bioactivity; natural products; biosynthesis; cytotoxicity; antimicrobial activity; deep sea

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Selected Papers from the 2025 Symposium on Marine Microbiology in China

edited by

Xuefeng Zhou

Xinpeng Tian

and

Yunxue Guo

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1057 | Submission Open

Keywords: marine microorganisms; marine natural products; marine toxins; biosynthesis; chemical ecology; marine biotechnology; molecular biology; artificial intelligence

Marine Algal Biotechnology and Applications—2nd Edition

edited by

Patrizia Casella

submission deadline 31 Jan 2026 | 1 articles | Viewed by 389 | Submission Open

Keywords: microalgae; seaweed; alternative protein sources; fatty acids; high-value compounds; biofuels; biomaterials; sustainability; circularity; biotechnologies

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine-Derived Bioactive Compounds with Potential Applications for Retinal Health

edited by

Yoko Miura

submission deadline 31 Jan 2026 | 1 articles | Viewed by 318 | Submission Open

Keywords: marine-derived compounds; retina; retinal pigment epithelium; age-related macular degeneration; antioxidants; anti-inflammatory mechanisms; neuroprotection

(This special issue belongs to the Section Marine Pharmacology)

Biotechnological Applications of Marine Enzymes, 2nd Edition

edited by

Pasquale De Luca

and

Chiara Lauritano

submission deadline 31 Jan 2026 | Viewed by 222 | Submission Open

Keywords: enzymes; heterologous expression; marine organisms; omics technologies; genome mining; bioactivity screening; protein structure; biotechnological applications

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Antioxidant and Antimicrobial Compounds in Marine Algae

edited by

Antonio León-Vaz

submission deadline 31 Jan 2026 | Viewed by 172 | Submission Open

Keywords: antibacterial; antiviral; macroalgae; microalgae; natural products; oxidative stress

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Terpenoids 2025

edited by

Wei Cheng

and

Junfeng Wang

submission deadline 31 Jan 2026 | Viewed by 166 | Submission Open

Keywords: marine terpenoids; separation; synthesis; biosynthesis; bioactivity; structure– activity relationship

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Bioprospecting of Marine Microalgae

edited by

Xiaojin Song

submission deadline 31 Jan 2026 | Viewed by 141 | Submission Open

Keywords: marine microalgae; bioprospecting; biomass valorization; nutraceuticals; applications

Research on Marine-Derived Functional Foods

edited by

Constantina Nasopoulou

submission deadline 31 Jan 2026 | Viewed by 71 | Submission Open

Keywords: marine organisms; omega-3 fatty acids; peptides; antioxidants; anti-inflammatory effect; cardioprotective activity; innovative processing methods; bioavailability; safety; stability

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Neuroprotective Effects of the Marine-Derived Compounds

edited by

Yi Zhang

and

Longjian Zhou

submission deadline 31 Jan 2026 | Viewed by 65 | Submission Open

Keywords: marine neuroprotectants; discovery; structural elucidation; methodology; bioactivities; mechanism of action; behavior; network pharmacology

(This special issue belongs to the Section Marine Pharmacology)

Marine Polysaccharides with Anticoagulant and Antimicrobial Activity

edited by

Poonam Sharma

submission deadline 31 Jan 2026 | Viewed by 54 | Submission Open

Keywords: marine polysaccharides; sulfated polysaccharides; anticoagulant activity; antimicrobial activity; antibiofilm features; antiviral agents; antibacterial agents; antiparasitic agents; antifungal agents; co-infections and superinfections

(This special issue belongs to the Section Biomaterials of Marine Origin)

Marine Enzymes in Nutraceuticals and Cosmeceuticals: Functional Innovation from the Ocean

edited by

Yonghui Zhang

submission deadline 31 Jan 2026 | Viewed by 45 | Submission Open

Keywords: marine enzymes; nutraceuticals; cosmeceuticals; bioactive compounds; enzyme engineering

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

High-Value-Added Resources Recovered from Marine By-Products

edited by Rong Cao and

Yongqiang Zhao

submission deadline 15 Feb 2026 | 1 articles | Viewed by 1437 | Submission Open

Keywords: marine by-products; bioactive compounds; marine enzymes; nutraceuticals; peptide isolation; polysaccharide extraction; green extraction technologies; microbial fermentation; marine biomimetics

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Biopolymers and Their Applications in Drug Delivery, 2nd Edition

edited by

Leto-Aikaterini Tziveleka

Efstathia Ioannou

and

Vassilios Roussis

submission deadline 15 Feb 2026 | 1 articles | Viewed by 1346 | Submission Open

Keywords: marine biomaterials; drug delivery; gene delivery; protein delivery; drug targeting; controlled release; hydrogels; particles; fibers; membranes

(This special issue belongs to the Section Biomaterials of Marine Origin)

Marine Natural Products as Anticancer Agents, 5th Edition

edited by

Celso Alves

and

Marc Diederich

submission deadline 15 Feb 2026 | 1 articles | Viewed by 388 | Submission Open

Keywords: anticancer; anti-tumor; immune; molecular targets; co-cultures; 3D culture models; marine natural products; receptors; proteins; molecular modeling; chemical synthesis; immune-modulatory

(This special issue belongs to the Section Marine Pharmacology)

Marine Natural Products as Enzyme Inhibitors

edited by

Patrizia Diana

submission deadline 15 Feb 2026 | Viewed by 58 | Submission Open

Keywords: marine natural products; enzyme inhibitors; marine microorganisms; marine drug target; drug discovery; molecular docking; protein kinase; enzyme altered pathway

(This special issue belongs to the Section Marine Pharmacology)

Bioactive Specialized Metabolites from Marine Plants

edited by

Sylvia Urban

submission deadline 28 Feb 2026 | 4 articles | Viewed by 10678 | Submission Open

Keywords: marine plants; algae; seaweeds; bioactive; drug discovery; specialized metabolites; isolation

(This special issue belongs to the Section Marine Pharmacology)

Marine Polysaccharides-Based Biomaterials

edited by

Raul J. Bernardino

and

Clélia Neves Afonso

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5011 | Submission Open

Keywords: marine polysaccharides; nutraceuticals; bioactive compounds; antioxidants; bioactive carbohydrates; algal polysaccharides; marine natural products; biopolymers; marine biotechnology

(This special issue belongs to the Section Biomaterials of Marine Origin)

Marine Carotenoids: Properties, Health Benefits, and Applications

edited by

Joanna Fiedor

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2377 | Submission Open

Keywords: marine carotenoids; distribution; biosynthesis; absorption; metabolism; bioavailability; functions; mechanisms of action; antioxidant activity; health effects; reduction in chronic disease risk; anti-cancer; anti-diabetes; anti-inflammatory; anti-obesity; and anti-photoaging activities; clinical; pharmaceutical; nutraceutical; and cosmeceutical applications; extraction; purification; and structure elucidation

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Research on Marine Compounds and Inflammation

edited by

Michela Geminiani

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2214 | Submission Open

Keywords: anti-inflammatory compounds; marine bioactive metabolites; inflammation; bioactive secondary metabolites; molecular targets of inflammation; marine algae; inflammatory pathways

(This special issue belongs to the Section Marine Pharmacology)

Marine Carotenoids and Potential Therapeutic Benefits

edited by Micaela Giani

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1453 | Submission Open

Keywords: carotenoid; antioxidant; biomedicine; health; nutraceutical; pigment; pharmacology; oxidative stress; anticancer; metabolism

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Total Synthesis, Semisynthesis and Analogue Synthesis of Bioactive Marine Natural Products

edited by

A. Ganesan

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1300 | Submission Open

Keywords: marine natural products; total synthesis; semisynthesis; biological activity; lead discovery and optimisation; medicinal chemistry

Marine Sulfated Polysaccharides and Their Biomedical Applications

edited by

Seung-U Son

submission deadline 28 Feb 2026 | 1 articles | Viewed by 450 | Submission Open

Keywords: marine sulfated polysaccharide; ulvan; fucoidan; galactan; algae; immunoregulation; anti-cancer; anti-obesity; biomedical application; structural analysis

(This special issue belongs to the Section Marine Pharmacology)

Marine Genomics and Metabolomics

edited by

Gerardo Della Sala

and

Fortunato Palma Esposito

submission deadline 28 Feb 2026 | Viewed by 191 | Submission Open

Keywords: marine microorganisms; marine natural products; metabolomics; genomics; heterologous expression; genome mining; biosynthetic gene clusters; mass spectrometry; molecular networking; NMR

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine-Derived Functional Foods and Nutraceuticals: Novel Compounds, Mechanisms, and Therapeutic Potential

edited by Jun Yang and

Xianxiang Chen

submission deadline 28 Feb 2026 | Viewed by 139 | Submission Open

Keywords: marine active compounds; functional foods; nutritional interventions; molecular mechanisms; targeted delivery

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Extremophiles and Their Metabolites

edited by

Yi Wang

submission deadline 28 Feb 2026 | Viewed by 123 | Submission Open

Keywords: marine extremophiles; natural products; enzymes; biosynthesis; structure elucidation; genome mining; bioprospecting

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine-Derived Compounds to Counteract Oxidative Stress and Inflammation in the Skin

edited by

Sinemyiz Atalay Ekiner

submission deadline 28 Feb 2026 | Viewed by 101 | Submission Open

Keywords: marine-derived compounds; oxidative stress; inflammation; redox metabolism; skin oxidative stress; skin inflammation; cutaneous inflammatory disease; skin cancer

Marine Compounds as Cosmetic Ingredients

edited by

Erika Baldini

and

Elisa Durini

submission deadline 28 Feb 2026 | Viewed by 101 | Submission Open

Keywords: marine compounds; cosmetic ingredients; skincare; formulation strategies; sustainable sourcing

Marine Bioactives in Nanotechnology

edited by Gary Smejkal and Nicholas Skizim

submission deadline 28 Feb 2026 | Viewed by 97 | Submission Open

Keywords: nanotechnology; pharmaceuticals; nutraceutricals; cosmeceuticals; marine compounds; nanoscale

Sustainable Extraction and Valorization of Marine Bioactive Compounds

edited by

Danay Carrillo-Nieves

submission deadline 28 Feb 2026 | Viewed by 61 | Submission Open

Keywords: green extraction; marine bioactive compounds; sustainable valorization; blue biotechnology; circular bioeconomy

Marine Toxins Driving Next-Generation Therapeutics and Technologies

edited by

Cherie Motti

Scott F. Cummins

and

Richard J. Harris

submission deadline 28 Feb 2026 | Viewed by 34 | Submission Open

Keywords: marine venoms; marine toxins including neurotoxins; marine natural products; marine peptides; ecological function of marine toxins; biochemical diversity; therapeutic applications; metabolomics; proteomics; transcriptomics

(This special issue belongs to the Section Marine Toxins)

Innovations in Marine Algal Biotechnology: From Bioprocessing to Applications

edited by Maria Elena Barone

submission deadline 1 Mar 2026 | Viewed by 68 | Submission Open

Keywords: marine natural products; biorefinery; antimicrobials; antioxidants; pigments; anticancer agents; microalgae; macroalgae; bioprocessing; marine bio-commodities

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Polysaccharides and Phytochemicals from Marine Resources: Structure, Activity, and Applications

edited by

Lijun You

submission deadline 1 Mar 2026 | Viewed by 35 | Submission Open

Keywords: isolation; structure; polysaccharide; phytochemicals; identification; biological activity

(This special issue belongs to the Section Marine Pharmacology)

Applications of Marine Microalgal Biotechnology

edited by

Chaogang Wang

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1045 | Submission Open

Keywords: microalgae; biotechnology; synthetic biology; metabolic engineering; bioprocess engineering; fermentation; biochemistry; natural compounds; marine drugs

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Sustainable High-Value Applications of Marine Side Streams

edited by

Vítor Spínola

submission deadline 15 Mar 2026 | Viewed by 69 | Submission Open

Keywords: marine side streams; circular bioeconomy; sustainable valorization; high-value applications; bioactive compounds; by-products; biorefinery

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

The Biological Significance of Fucose-Based Polysaccharides and Oligosaccharides from the Sea

edited by

You-Jin Jeon

submission deadline 15 Mar 2026 | Viewed by 39 | Submission Open

Keywords: fucose; fucoidan; oligosaccharide; human milk oligosaccharides (HMOs); prebiotic; probiotic; synbiotic; microbiome; anti-inflammation; gut health; brown algae; holothuria; fucosylated chondroitin sulfate

(This special issue belongs to the Section Marine Pharmacology)

Proteomic Studies for the Identification and Characterization of Marine Bioactive Molecules, 2nd Edition

edited by

Nedeljka Rosic

submission deadline 31 Mar 2026 | 1 articles | Viewed by 3334 | Submission Open

Keywords: omics; proteomics; bioproducts; anti-bacterial; anti-tumor; anti-viral; anti-aging; anti-inflammatory; anti-fungal

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Eco-Friendly Extraction Processes for Obtaining Marine Bioactive Products

edited by

Liaqat Zeb

submission deadline 31 Mar 2026 | Viewed by 318 | Submission Open

Keywords: marine natural products; integrated biorefinery; sustainable extraction; marine bioresources; green solvent extraction; marine bioprocessing; marine sustainability; advanced extraction technologies

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Unexploited Marine Resources as Novel Sources of Antioxidants

edited by

Hugo Alexandre Oliveira Rocha

and Rafael Barros Gomes Câmara

submission deadline 31 Mar 2026 | Viewed by 24 | Submission Open

Keywords: marine natural products; antioxidant compounds; algae-derived antioxidants; marine microorganisms; oxidative stress; bioactivity metabolites; nutraceuticals; marine biotechnology; drug discovery; sustainable bioprospecting

(This special issue belongs to the Section Marine Pharmacology)

Enzymes Derived from Marine Sources

edited by

Stephen A. Jackson

submission deadline 31 Mar 2026 | Viewed by 19 | Submission Open

Keywords: marine enzymes; CAZymes; proteases; lipases; extremozymes; psychrophilic enzymes; halophilic enzymes; industrial

(This special issue belongs to the Section Marine Pharmacology)

Advances in Research on Fucoidan: Potential as Drug and Functional Food

edited by

Dineth Pramuditha Nagahawatta

and Nisansala Liyanage

submission deadline 31 Mar 2026 | Viewed by 16 | Submission Open

Keywords: fucoidan; functional oligo-fucoidans; structure– function; green extraction/biorefinery; drug delivery & biomaterials; gut microbiome; immunomodulation & inflammation; oncology adjuvant; cardiometabolic/atherosclerosis; quality control & regulatory science

Bioactive Natural Products from Marine Cyanobacteria: From Discovery to Valorization

edited by

Rosário Martins

and

Marisa Alexandra Freitas

submission deadline 31 Mar 2026 | Viewed by 14 | Submission Open

Keywords: marine cyanobacteria; natural products; bioactive metabolites; anticancer compounds; antimicrobial agents; pigment valorization; sustainable bioprocessing; biosynthetic pathways; synthetic biology; biotechnological applications

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Innovative Marine Nanomaterials in Targeted Drug Delivery

edited by

Ioanna Pitterou

and

Anastasia Detsi

submission deadline 31 Mar 2026 | Viewed by 12 | Submission Open

Keywords: marine nanomaterials; drug delivery systems; marine polysaccharides (e.g.; chitosan; fucoidan; alginate); nanocarriers and nanostructures; targeted therapy and controlled release; marine-derived bioactive compounds; cancer nanomedicine; biocompatibility and biodegradability; nano-biomaterials from the marine environment; translational nanotechnology

(This special issue belongs to the Section Biomaterials of Marine Origin)

Natural Products from Soft Corals and Their Associated Microbes

edited by Ming-Zhi Su

submission deadline 31 Mar 2026 | Viewed by 5 | Submission Open

Keywords: soft corals; soft coral-associated microbes; marine natural products; synthetic derivatives based on marine natural products; biosynthesis pathways; bioactivity; chemical ecology; pharmacological mechanism

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

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