Special Issues

Marine Drugs publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metabolic Regulation Functions and Mechanisms of Marine Bioactive Compounds
edited by
submission deadline 15 Oct 2025 | Viewed by 174 | Submission Open
Keywords: marine natural products; biological activity; compound isolation/characterization; marine extracts; drug discovery; therapeutic applications; human immunity; biomedical applications; anti-inflammatory; marine-based functional foods; metabolic disorders; metabolic pathways
(This special issue belongs to the Section Marine Pharmacology)
Marine Algal Chemical Ecology 2024
edited by Bethanie R. Edwards
submission deadline 31 Oct 2025 | 4 articles | Viewed by 8053 | Submission Open
Keywords: chemical ecology; marine microbiology; marine algae; omics; community dynamics
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Zebrafish Models in Marine Drug Discovery
edited by Xiaobin Li
submission deadline 31 Oct 2025 | 4 articles | Viewed by 7945 | Submission Open
Keywords: marine drugs; zebrafish model; active natural product; bioactivity screening; mechanism of action; activity evaluation
(This special issue belongs to the Section Marine Pharmacology)
Marine Biorefinery for Bioactive Compounds Production
edited by and
submission deadline 31 Oct 2025 | 6 articles | Viewed by 7619 | Submission Open
Keywords: marine biorefinery; bioactive compounds; marine biotechnology; sustainable production; marine natural products; extraction technologies; biochemical characterization; pharmaceutical applications; nutraceuticals; process scale-up and intensification; industrial applications; life cycle assessment
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Marine-Derived Bioactive Substances and Their Mechanisms of Action
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 7079 | Submission Open
Keywords: marine bioactive metabolite; antioxidant; anticancer; immunomodulatory action; cell signaling; mechanisms of action
(This special issue belongs to the Section Marine Pharmacology)
Marine Bioactive Compounds for Skin Health
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3458 | Submission Open
Keywords: marine bioactive compounds; marine metabolites; skin health; skin inflammation; marine pharmaceuticals
Marine Microorganisms Bioprospecting
edited by and Qingbo Zhang
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2456 | Submission Open
Keywords: marine microorganisms; marine natural products; bioactivity screening; structure-activity relationship; genome mining; natural product biosynthesis; biocatalysis; metabolic engineering; synthetic biology; pharmacological mechanisms
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Marine Antiparasitic Agents, 2nd Edition
edited by , Anabela Cordeiro-da-Silva and Diana Resende
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1966 | Submission Open
Keywords: antiparasitic; marine agents; safe extraction; green chemistry; parasites; helminths; protozoans
(This special issue belongs to the Section Marine Pharmacology)
Enzyme Inhibitors from Marine Resources, 2nd Edition
edited by Francesc Xavier Avilés and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1632 | Submission Open
Keywords: marine inhibitors of enzymes; non-peptide and peptide/protein inhibitors; isolation and characterization; structure-function; genomics and proteomics; variety and evolution; biological role; biotechnology; drug screening and discovery; imaging and nano-technology; potential for therapeutics
(This special issue belongs to the Section Marine Pharmacology)
Research on Marine Antimicrobial Peptides
edited by and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1020 | Submission Open
Keywords: marine antimicrobial peptides; structural diversity; host defense mechanisms; multidrug-resistant pathogens; mining and exploration; biosynthesis; anti-infective mechanism; immunoregulation; nanoparticle-based delivery systems; AI-based prediction technologies
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Pharmacognostic Potential of Seaweed Extracts and Metabolites
edited by Rafael Félix
submission deadline 31 Oct 2025 | Viewed by 231 | Submission Open
Keywords: pharmacognosy; marine natural products; bioactive compounds; human health; veterinary; agriculture; emerging diseases; antimicrobial resistance; extraction
Microalgae Cultures and Their Value in Nutraceutical/Cosmetic Industry submission deadline 31 Oct 2025 | Viewed by 165 | Submission Open
Keywords: microalgae industrialization; active biomolecules; antioxidants; prebiotics; ω -3 fatty acids
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Genome Mining and Discovery of Marine Novel Antibiotics
edited by Jianying Han
submission deadline 31 Oct 2025 | Viewed by 163 | Submission Open
Keywords: genome mining; marine natural products; antibiotic discovery; marine actinobacteria; marine fungi; biosynthetic gene clusters; metabolomics; metagenomics; structure elucidation; microbial technology; host– microbe interaction
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Marine Microbial Metabolites: Isolation, Bioactivity, and Therapeutic Potential
edited by
submission deadline 31 Oct 2025 | Viewed by 159 | Submission Open
Keywords: marine natural products; marine microorganism; metabolites; isolation; structure elucidation; bioactive; therapeutic potential
Bioactive Compounds from Marine Invertebrates
edited by
submission deadline 31 Oct 2025 | Viewed by 103 | Submission Open
Keywords: metabolite; peptide; marine invertebrate; marine natural products; biotechnological application; drugs; metabolomic; proteomic; bioinformat
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Marine Natural Products Against Inflammatory-Based Diseases submission deadline 31 Oct 2025 | Viewed by 88 | Submission Open
Keywords: N-3 PUFA; marine-derived ingredients; nutraceutical; triglycerides; cardiovascular diseases; obesity; metabolic syndrome; neurodegenerative disease; rheumatoid arthritis; inflammatory bowel diseases; cancer
(This special issue belongs to the Section Marine Pharmacology)
Defying the Odds: Innate Immunity in Invertebrates Living in Deep-Sea Extreme Environments
edited by
submission deadline 31 Oct 2025 | Viewed by 83 | Submission Open
Keywords: deep-sea ecosystems; marine extreme environments; deep-sea invertebrates; invertebrate innate immunity; evolutionary immunology; secondary metabolites from deep sea invertebrates
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Non-Regulated Marine Toxins
edited by
submission deadline 31 Oct 2025 | Viewed by 79 | Submission Open
Keywords: non-regulated marine toxins; identification and characterization; structural elucidation; mechanisms of biosynthesis; biological evaluation; toxicity; pharmacology; toxicology and risk assessment; methods for the detection and analysis; metabolism; biotransformation; applications of non-regulated marine toxins in medicine; biotechnology and agriculture; evidence for geographical/temporal expansion of non-regulated marine toxins
(This special issue belongs to the Section Marine Toxins)
Marine Bioactive Substances: From By-Products to Innovative Applications
edited by
submission deadline 31 Oct 2025 | Viewed by 59 | Submission Open
Keywords: bioactive compounds; biological activity; peptide; protein hydrolysates; extract methods; molecular structures; functional characteristics; by-product utilization; bioaccessibility and bioavailability
Advances in Secondary Metabolites from Mangrove Holobiont
edited by and
submission deadline 1 Nov 2025 | 3 articles | Viewed by 2348 | Submission Open
Keywords: mangrove holobiont; natural products; pharmacological activities; biosynthetic mechanisms; symbionts communicate; lead compound
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Applications of Lipids from Marine Sources submission deadline 15 Nov 2025 | 4 articles | Viewed by 9242 | Submission Open
Keywords: lipidomics; marine organisms; functional foods; blue biotechnology; marine lipids
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Marine Anti-Inflammatory and Antioxidant Agents, 5th Edition submission deadline 15 Nov 2025 | 1 articles | Viewed by 773 | Submission Open
Keywords: marine organisms; inflammation; cytokines; antioxidant agents; anti-inflammatory gents; oxidative stress; ROS/RNS; NF-κ B; mitochondrial oxidative; drug delivery
(This special issue belongs to the Section Marine Pharmacology)
Jellyfish-Derived Compounds
edited by
submission deadline 15 Nov 2025 | 1 articles | Viewed by 714 | Submission Open
Keywords: jellyfish proteins and peptides; bioactive compounds; anticancer; photoprotection; jellyfish collagen; jellyfish symbionts; cosmetics and cosmeceuticals; nutraceuticals; biomaterials; novel foods; jellyfish-associated microbiome
(This special issue belongs to the Section Biomaterials of Marine Origin)
Marine Natural Products with Anti-aging Activity
edited by Maria Elisa Giuliani and
submission deadline 30 Nov 2025 | 4 articles | Viewed by 15633 | Submission Open
Keywords: aging; age-related diseases; longevity; healthspan; marine molecules; marine organisms; drug discovery
(This special issue belongs to the Section Marine Pharmacology)
Marine Natural Products as Anticancer Agents, 4th Edition
edited by and
submission deadline 30 Nov 2025 | 10 articles | Viewed by 14031 | Submission Open
Keywords: anticancer; anti-tumor; immune; molecular targets; co-cultures; 3D culture models; marine natural products; receptors; proteins; molecular modeling; chemical synthesis; immune-modulatory
(This special issue belongs to the Section Marine Pharmacology)
Enzymes from Marine By-Products and Wastes
edited by
submission deadline 30 Nov 2025 | 4 articles | Viewed by 12563 | Submission Open
Keywords: enzymes; proteases; lipases; carbohydrases; chitinases; transglutaminases; fisheries and aquaculture; by-products and waste; microbial fermentation; enzymatic hydrolysis; protein hydrolysates
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Toxins as Marine-Based Drug Discovery, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 5 articles | Viewed by 9126 | Submission Open
Keywords: neurotoxins; marine natural compounds; sodium channels; potassium channels; calcium channels; chloride ion channels; TRP channels; ASIC channels; opiate receptors; acetylcholine receptors; NMDA receptors; antibiotics; antimicrobial peptides; gastropod venom peptides; sea anemone toxins
(This special issue belongs to the Section Marine Toxins)
Marine Natural Products with Immunomodulatory Activity
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 8258 | Submission Open
Keywords: marine natural products; drug discovery; immune system; immunomodulatory activity; immune activation; immune modulation; structural characterization; chemical synthesis
(This special issue belongs to the Section Marine Pharmacology)
The Extraction and Application of Functional Components in Algae submission deadline 30 Nov 2025 | 4 articles | Viewed by 6066 | Submission Open
Keywords: algae functional components; extraction of bioactive molecules; health benefits; nutraceuticals; applications (food; pharmaceutical; wellness and care; etc.)
Bioactive Metabolites Produced by Marine Cyanobacteria and Other Microalgae submission deadline 30 Nov 2025 | 2 articles | Viewed by 2851 | Submission Open
Keywords: cyanobacteria; microalgae; natural products; secondary metabolites; genome mining; extraction and isolation; structural analysis; biological activity; molecular targets; pharmaceutical application; biotechnological potential; toxicity
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Green Extraction of High-Value Compounds in Marine Algae submission deadline 30 Nov 2025 | 2 articles | Viewed by 2390 | Submission Open
Keywords: green extraction methods; green solvents; biorefinery; ultrasonic assisted extraction; microwave assisted extraction; supercritical fluid extraction; subcritical water extraction; pressurized liquid extraction; pulsed electric field; ionic liquids
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
New Methods in Extraction and Isolation of Marine Natural Products
edited by Débora Tomazi Pereira and Paz García-García
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1682 | Submission Open
Keywords: green extraction and isolation of marine natural products; marine extraction methods; isolation techniques; marine natural products; bioactive marine compounds; marine chemistry
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Sustainable Approaches for the Biotechnological Development of Marine Microalgae-Derived Products submission deadline 30 Nov 2025 | 1 articles | Viewed by 1066 | Submission Open
Keywords: marine bioactive compounds; microalgae; green solvents; sustainable extraction methods; sustainable formulations
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Marine Bioactive Peptides—Structure, Function and Application, 3rd Edition
edited by and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 858 | Submission Open
Keywords: marine peptides; protein hydrolysate; biotechnological production; structure identification; structural modification; bioactivity and function; structure– function relationship; bioavailability; nutritional value; functional foods; application
Marine Biomaterials for Dental Applications
edited by Marcela R. Carrilho and Walter Antonio Bretz
submission deadline 30 Nov 2025 | 1 articles | Viewed by 548 | Submission Open
Keywords: marine products; marine biomimicry; functional biomaterials; dentistry; oral health
(This special issue belongs to the Section Biomaterials of Marine Origin)
Marine Microalgae Culture and Active Substance Development
edited by and
submission deadline 30 Nov 2025 | Viewed by 544 | Submission Open
Keywords: marine microalgae; algal active substances; cultivation optimization; photobioreactor; pigments; PUFAs (polyunsaturated fatty acids); polysaccharides; separation and purification; efficacy evaluation
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Marine Alga-Sourced Ingredients as Functional Foods and Nutritional Supplements
edited by
submission deadline 30 Nov 2025 | Viewed by 282 | Submission Open
Keywords: marine products; functional foods; nutraceuticals; algal ingredients; extracts; synergistic effects; dietary supplements; bioactive compounds; algal metabolites; extraction techniques
Marine Lectins: Structures, Functions and Applications
edited by
submission deadline 30 Nov 2025 | Viewed by 156 | Submission Open
Keywords: marine organism; lectin; structure; function; molecular evolution; application; biomarker; biosensor; diagnosis; drug; cosmeceutical; nutraceutical
Pharmacological Potential of Marine Natural Products, 3rd Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 94 | Submission Open
Keywords: marine natural products; marine drugs; biological activity; structure– activity relationship; antitumor activity; antiviral activity; antibacterial activity; structural determination; mechanism of action
(This special issue belongs to the Section Marine Pharmacology)
Marine Natural Products with Anti-Prostate Cancer Activity
edited by and
submission deadline 30 Nov 2025 | Viewed by 59 | Submission Open
Keywords: marine natural products; anti-PCa activity; biosynthetic pathway; structure– activity relationships; molecular docking; network pharmacology; experimental validation; molecular dynamics simulations; pharmacological mechanism
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Marine Compounds as Inhibitors
edited by Seoung Rak Lee
submission deadline 1 Dec 2025 | Viewed by 74 | Submission Open
Keywords: marine natural products; bioactive compounds; enzyme inhibition; anticancer agents; antimicrobial agents; immunomodulators; structure– activity relationship; inhibitors
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Celebrating the 100th Anniversary of Ocean University of China: Potential Therapeutic Benefits of Marine Novel Natural Products
edited by Peng Fu and
submission deadline 15 Dec 2025 | 3 articles | Viewed by 2914 | Submission Open
Keywords: marine biotechnology; pharmacological profiling; marine anti-inflammatory agents; cancer therapeutics; infectious disease treatment; vascular disorder treatment; antithrombotic therapy; marine bioactive compounds; molecular targets; marine-derived therapeutics
(This special issue belongs to the Section Marine Pharmacology)
Marine Brown Algae-Derived Bioactive Polysaccharide Fucoidans
edited by Hsien-Yeh Hsu
submission deadline 15 Dec 2025 | Viewed by 226 | Submission Open
Keywords: marine brown algae-derived fucoidan; polysaccharides; bioactivity; medical; fucoidan in human clinical trials; cosmetics; nutraceuticals; biotechnological
Marine Algae as Functional Foods
edited by Tânia Sofia Tavares
submission deadline 15 Dec 2025 | Viewed by 165 | Submission Open
Keywords: seaweed; bioactivity; extraction; sustainability; industry; food
Bioactive Molecules from Extreme Environments III
edited by
submission deadline 31 Dec 2025 | 7 articles | Viewed by 27134 | Submission Open
Keywords: marine natural products; bioactive molecules; metabolites; anti-UV molecules; enzymes; peptides; extreme environments; polar regions; deep sea; hydrothermal vents; UV radiation
Chemoinformatics for Marine Drug Discovery
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 7755 | Submission Open
Keywords: chemoinformatics; dereplication; machine learning techniques; mnps databases; chemical space; quantitative structure– activity relationship (QSAR); molecular docking; computer– aided design design (CADD); computer– assisted structure elucidation (CASE); drug discovery
(This special issue belongs to the Section Marine Pharmacology)
Biologically Active Compounds from Marine Invertebrates 2025
edited by Crisalejandra Rivera-Pérez
submission deadline 31 Dec 2025 | 3 articles | Viewed by 6332 | Submission Open
Keywords: bioactive compounds; antimicrobial; antioxidants; anticancerogenic; angiotensin activity; biomedicine; biotechnology; marine natural products
(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)
Algal Cultivation for Obtaining High-Value Products, 2nd Edition submission deadline 31 Dec 2025 | 5 articles | Viewed by 5957 | Submission Open
Keywords: algae; photosynthesis; antioxidant; stress; carotenoids; polyphenols; physiology; high-value product; photobioreactor; biotechnology; fatty acids
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
Structural Diversity in Marine Natural Products
edited by and
submission deadline 31 Dec 2025 | 5 articles | Viewed by 4700 | Submission Open
Keywords: marine natural products; marine biotechnology; bioactive secondary metabolites; structural diversity; isolation and structure elucidation; biosynthesis; drug candidates
(This special issue belongs to the Section Structural Studies on Marine Natural Products)
Fermentation Processes for Obtaining Marine Bioactive Products
edited by In Yung Sunwoo
submission deadline 31 Dec 2025 | 2 articles | Viewed by 4151 | Submission Open
Keywords: marine biomass; microorganism; fermentation; marine bioactive compounds; application
(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)
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