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Marine Drugs publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Marine Natural Products as Anticancer Agents, 4th Edition

edited by

Celso Alves

and

Marc Diederich

submission deadline 15 May 2025 | 6 articles | Viewed by 7399

Keywords: anticancer; anti-tumor; immune; molecular targets; co-cultures; 3D culture models; marine natural products; receptors; proteins; molecular modeling; chemical synthesis; immune-modulatory

(This special issue belongs to the Section Marine Pharmacology)

Marine-Derived Terpenes: Chemistry, Synthesis and Their Therapeutic Potential

edited by

Jinmei Xia

and Wenhai Xiao

submission deadline 15 May 2025 | 5 articles | Viewed by 6654

Keywords: marine; terpene; structure elucidation; biosynthetic pathway; synthetic method; bioactivity; therapeutic application; anticancer; antimicrobial

(This special issue belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)

Marine Biotoxins 3.0

edited by

Jordi Molgó

submission deadline 31 May 2025 | 7 articles | Viewed by 14007 | Submission Open

Keywords: marine biotoxins; mechanism of action; pharmacology; cellular and molecular targets; signaling pathways; metabolism; toxicity; risk factors; molecular interactions; therapeutic potential

(This special issue belongs to the Section Marine Toxins)

Marine Natural Products with Anti-aging Activity

edited by Maria Elisa Giuliani and

Marco Malavolta

submission deadline 31 May 2025 | 4 articles | Viewed by 12994 | Submission Open

Keywords: aging; age-related diseases; longevity; healthspan; marine molecules; marine organisms; drug discovery

(This special issue belongs to the Section Marine Pharmacology)

Value-Added Products from Marine Fishes

edited by Helena Maria Lourenço and

Sónia Pedro

submission deadline 31 May 2025 | 5 articles | Viewed by 11545 | Submission Open

Keywords: marine fishes; bioactivity; health benefits; blue economy; chronic diseases

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Proteins and Enzymes: Bioactivities and Medicinal Applications

edited by

Min-Jie Cao

and Asami Yoshida

submission deadline 31 May 2025 | 5 articles | Viewed by 10409 | Submission Open

Keywords: proteins; proteinases; glycolytic enzyme; enzymes; peptides; bioactive compounds; bioactivities; medicine

(This special issue belongs to the Section Marine Pharmacology)

Advances of Marine-Derived Enzymes

edited by

Olafur Fridjonsson

submission deadline 31 May 2025 | 8 articles | Viewed by 10348 | Submission Open

Keywords: marine enzymes; enzyme products; enzyme properties; exploitation potentials; marine biotechnology; biorefining; production technology

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Toxins as Marine-Based Drug Discovery, 2nd Edition

edited by

Steve Peigneur

submission deadline 31 May 2025 | 5 articles | Viewed by 7742 | Submission Open

Keywords: neurotoxins; marine natural compounds; sodium channels; potassium channels; calcium channels; chloride ion channels; TRP channels; ASIC channels; opiate receptors; acetylcholine receptors; NMDA receptors; antibiotics; antimicrobial peptides; gastropod venom peptides; sea anemone toxins

(This special issue belongs to the Section Marine Toxins)

The Extraction and Application of Functional Components in Algae

edited by

Aurora Silva

Miguel Ángel Prieto Lage

Clara Grosso

and

Maria Fátima Sá Barroso

submission deadline 31 May 2025 | 3 articles | Viewed by 4059 | Submission Open

Keywords: algae functional components; extraction of bioactive molecules; health benefits; nutraceuticals; applications (food; pharmaceutical; wellness and care; etc.)

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Application of Marine Nature Products to Reduce Oxidative Stress

edited by

Chieh-Hsi Wu

submission deadline 31 May 2025 | 2 articles | Viewed by 3862 | Submission Open

Keywords: free radicals; inflammation; marine products; microbiota; system biology; signal transduction

(This special issue belongs to the Section Marine Pharmacology)

Fermentation Processes for Obtaining Marine Bioactive Products

edited by In Yung Sunwoo

submission deadline 31 May 2025 | 2 articles | Viewed by 3153 | Submission Open

Keywords: marine biomass; microorganism; fermentation; marine bioactive compounds; application

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Extremophiles: Adaptations and Biotechnological Applications

edited by

Sandra Pucciarelli

submission deadline 31 May 2025 | 1 articles | Viewed by 1613 | Submission Open

Keywords: bioactive molecules; extremozymes; polar regions; extremophiles; biomaterials

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Sulfated Glycans

edited by

Yuefan Song

submission deadline 31 May 2025 | 1 articles | Viewed by 1208 | Submission Open

Keywords: marine sulfated glycans; glycosaminoglycan mimetics; algal glycans; fucoidans; bioactivity; biomedical application; biomaterial

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

New Methods in Extraction and Isolation of Marine Natural Products

edited by Débora Tomazi Pereira and Paz García-García

submission deadline 31 May 2025 | 1 articles | Viewed by 375 | Submission Open

Keywords: green extraction and isolation of marine natural products; marine extraction methods; isolation techniques; marine natural products; bioactive marine compounds; marine chemistry

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Bioactive Compounds from Marine Diatoms: Innovative Applications

edited by

Mostefa Fodil

submission deadline 31 May 2025 | Viewed by 147 | Submission Open

Keywords: marine diatoms; bioactive compounds; natural products; anticancer; anti-inflammatory; antimicrobial; antioxidants; biotechnology; marine biochemistry; drug discovery

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Algae as Functional Foods

edited by Tânia Sofia Tavares

submission deadline 31 May 2025 | Viewed by 131 | Submission Open

Keywords: seaweed; bioactivity; extraction; sustainability; industry; food

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Natural Products for Neglected Tropical Diseases

edited by Andre G. Tempone and João Henrique Ghilardi Lago

submission deadline 31 May 2025 | Viewed by 103 | Submission Open

Keywords: drug discovery; leishmaniasis; Chagas disease; African trypanosomiasis; marine microbiology; neglected diseases; marine compounds; antiviral; antimicrobial; antifungal

(This special issue belongs to the Section Marine Pharmacology)

Marine Biomaterials for Dental Applications

edited by Marcela R. Carrilho and Walter Antonio Bretz

submission deadline 31 May 2025 | Viewed by 93 | Submission Open

Keywords: marine products; marine biomimicry; functional biomaterials; dentistry; oral health

(This special issue belongs to the Section Biomaterials of Marine Origin)

High-Value-Added Resources Recovered from Marine By-Products

edited by Rong Cao and

Yongqiang Zhao

submission deadline 1 Jun 2025 | Viewed by 196 | Submission Open

Keywords: marine by-products; bioactive compounds; marine enzymes; nutraceuticals; peptide isolation; polysaccharide extraction; green extraction technologies; microbial fermentation; marine biomimetics

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Metabolic Regulation Functions and Mechanisms of Marine Bioactive Compounds

edited by

N. Liyanage

submission deadline 1 Jun 2025 | Viewed by 136 | Submission Open

Keywords: marine natural products; biological activity; compound isolation/characterization; marine extracts; drug discovery; therapeutic applications; human immunity; biomedical applications; anti-inflammatory; marine-based functional foods; metabolic disorders; metabolic pathways

(This special issue belongs to the Section Marine Pharmacology)

Marine Algal Biotechnology and Applications

edited by

Patrizia Casella

submission deadline 15 Jun 2025 | 4 articles | Viewed by 4986 | Submission Open

Keywords: microalgae; seaweed; alternative protein sources; fatty acids; high value compounds; biofuels; biomaterials; sustainability; circularity; biotechnologies

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Algal Cultivation for Obtaining High-Value Products, 2nd Edition

edited by

Cecilia Faraloni

and

Eleftherios Touloupakis

submission deadline 15 Jun 2025 | 3 articles | Viewed by 3106 | Submission Open

Keywords: algae; photosynthesis; antioxidant; stress; carotenoids; polyphenols; physiology; high-value product; photobioreactor; biotechnology; fatty acids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Exploiting Marine ‘Omics’ Technologies for the Biodiscovery of Marine Natural Products

edited by

Stephen A. Jackson

submission deadline 15 Jun 2025 | 1 articles | Viewed by 2150 | Submission Open

Keywords: ‘ omics’ ; genomics; metagenomics; metabolomics; specialized/secondary metabolism biosynthetic gene clusters

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Antiparasitic Agents, 2nd Edition

edited by

Carla Fernandes

, Anabela Cordeiro-da-Silva and Diana Resende

submission deadline 15 Jun 2025 | 1 articles | Viewed by 1397 | Submission Open

Keywords: antiparasitic; marine agents; safe extraction; green chemistry; parasites; helminths; protozoans

(This special issue belongs to the Section Marine Pharmacology)

Antimicrobial Compounds from Marine and Island Ecosystems: Exploration, Characterization, and Application

edited by

Ruoyu Mao

and Qingfen Guan

submission deadline 15 Jun 2025 | 1 articles | Viewed by 1110 | Submission Open

Keywords: marine and island ecosystems; antimicrobial compounds; immunomodulatory compounds; pharmaceuticals; nutraceuticals; mining; biotechnology; molecular structure; drug development

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Biosynthesis of Biologically Active Marine Natural Products 2025

edited by

Yiguang Zhu

submission deadline 15 Jun 2025 | Viewed by 567 | Submission Open

Keywords: marine microorganisms; marine plants and animals; genome mining; biosynthetic pathway enzymatic reaction mechanisms; marine bioactive compounds; structure elucidation; bioactivity screening; structure– activity relationship; pharmacological mechanism

Marine Brown Algae-Derived Bioactive Polysaccharide Fucoidans

edited by Hsien-Yeh Hsu

submission deadline 15 Jun 2025 | Viewed by 143 | Submission Open

Keywords: marine brown algae-derived fucoidan; polysaccharides; bioactivity; medical; fucoidan in human clinical trials; cosmetics; nutraceuticals; biotechnological

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Biotoxins: Detection, Environmental Behaviour and Toxic Effects

edited by

Jiangbing Qiu

and

Yang Liu

submission deadline 15 Jun 2025 | Viewed by 85 | Submission Open

Keywords: marine biotoxins; phycotoxins; detection and analysis methods; environmental behaviours; toxicology and risk assessment

(This special issue belongs to the Section Marine Toxins)

Bioactive Molecules from Extreme Environments III

edited by

Daniela Giordano

submission deadline 30 Jun 2025 | 7 articles | Viewed by 24167 | Submission Open

Keywords: marine natural products; bioactive molecules; metabolites; anti-UV molecules; enzymes; peptides; extreme environments; polar regions; deep sea; hydrothermal vents; UV radiation

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine-Derived Biomaterials for Tissue Regeneration

edited by

Tiago H. Silva

and Gabriela S. Diogo

submission deadline 30 Jun 2025 | 6 articles | Viewed by 15748 | Submission Open

Keywords: polymers; polysaccharides; minerals; ceramics; marine biomaterials; customized biomaterials; tissue regeneration; collagen; chitin and chitosan; fish by-products

(This special issue belongs to the Section Biomaterials of Marine Origin)

Marine Algae: Exploring Their Nutritional, Health, and Nutraceutical Potential

edited by

Leonel Pereira

and

Ana Marta Gonçalves

submission deadline 30 Jun 2025 | 7 articles | Viewed by 14777 | Submission Open

Keywords: seaweed; nutritional composition; health benefits; bioactive compounds; antioxidant properties; anti-inflammatory effects; anti-cancer potential; functional foods; dietary supplements; nutraceuticals; sustainability; extraction techniques; processing methods; human health

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Bioactive Natural Products from the Deep-Sea-Sourced Microbes

edited by

Bin-Gui Wang

and Siwen Niu

submission deadline 30 Jun 2025 | 9 articles | Viewed by 12697 | Submission Open

Keywords: deep-sea-sourced fungus; deep-sea-sourced actinomycetes; deep-sea-sourced bacteria; marine natural products; bioactive natural products; structure identification; antibacterial activity; antiviral activity; anti-inflammatory activity; cytotoxicity

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Diversity of Marine Fungi as a Source of Bioactive Natural Products, 2nd Edition

edited by

Dehai Li

submission deadline 30 Jun 2025 | 5 articles | Viewed by 6992 | Submission Open

Keywords: marine fungus; bioactivity; natural products; biosynthesis; cytotoxicity; antimicrobial activity; deep sea

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Marine Algal Compounds with Antimicrobial Activities

edited by

Adele Cutignano

submission deadline 30 Jun 2025 | 3 articles | Viewed by 6217 | Submission Open

Keywords: marine microalgae; marine macroalgae; secondary metabolites; structural characterization; AMR; antibiotic; antiviral

(This special issue belongs to the Section Marine Pharmacology)

Chemoinformatics for Marine Drug Discovery

edited by

Florbela Pereira

submission deadline 30 Jun 2025 | 4 articles | Viewed by 5215 | Submission Open

Keywords: chemoinformatics; dereplication; machine learning techniques; mnps databases; chemical space; quantitative structure– activity relationship (QSAR); molecular docking; computer– aided design design (CADD); computer– assisted structure elucidation (CASE); drug discovery

(This special issue belongs to the Section Marine Pharmacology)

Marine Polysaccharide-Based Biomaterials

edited by

Yang Liu

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5086 | Submission Open

Keywords: chitosan; alginate; agarose; nano-drug carrier; wound dressing; hydrogel

(This special issue belongs to the Section Biomaterials of Marine Origin)

Marine Bioactives for Functional Cosmetics with Health-Promoting Properties

edited by

Alexandros Tsoupras

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3029 | Submission Open

Keywords: skin inflammation; photo-oxidation; ageing; sustainable marine sources; marine bioactives; structure– activity relationship; synergism; skin health; skin protection; bio-functional; functional products; cosmetics; nutricosmetics; cosmeceuticals; pharmaceutical cosmetics; pharmaceutical ointments; sunscreen; sun oils; photo-protection; anti-inflammatory; anti-ageing; antioxidant; anti-melanoma; skin protection; fish; mollusks; macro-algae; micro-algae; seaweed; marine fungi; marine microorganisms; marine by-products

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Therapeutic Potential of Phlorotannins

edited by

Hyeon-Cheol Shin

Bong Ho Lee

and

Hye Jeong Hwang

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2924 | Submission Open

Keywords: phlorotannin; analytical; physicochemical; synthetic; theoretical; pharmacological

(This special issue belongs to the Section Marine Pharmacology)

Marine Microalgal Biorefinery for Bioactive Compound Production 2024

edited by

Xiaojin Song

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2800 | Submission Open

Keywords: bioengineering technologies; bioproducts; cultivation; fermentation; high throughput screening; marine microalgae; metabolic engineering; separation and purification processes; synthetic biology

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Natural Products as Regulators in Cell Signaling Pathway

edited by Faliang An

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2538 | Submission Open

Keywords: marine-derived natural products; cell signaling pathways; biological activities; pharmacological mechanisms; therapeutic strategies; structure– activity relationship

(This special issue belongs to the Section Marine Pharmacology)

Biotechnological Applications of Marine Photosynthetic Microorganisms

edited by Changhong Yao

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1830 | Submission Open

Keywords: marine microalgae; marine cyanobateria; biosynthesis; biotechnology; metabolic engineering; synthetic biology; microalgal cultivation; process modeling; extraction; high-value compounds

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Bio-Active Components from Marine Sponge

edited by

Sylvain Petek

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1533 | Submission Open

Keywords: sponges; isolation; synthesis; bioactivity; anti-cancer; anti-infective; human health; animal health; eco-friendly solution; chemical ecology

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine Microorganisms Bioprospecting

edited by

Junfeng Wang

and Qingbo Zhang

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1024 | Submission Open

Keywords: marine microorganisms; marine natural products; bioactivity screening; structure-activity relationship; genome mining; natural product biosynthesis; biocatalysis; metabolic engineering; synthetic biology; pharmacological mechanisms

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Discovery, Synthesis and Mechanism of Marine Drugs for Treating Cancer

edited by Lijun Wang and Chuanlong Guo

submission deadline 30 Jun 2025 | 1 articles | Viewed by 585 | Submission Open

Keywords: anti-tumor drugs; total synthesis; structural optimization; modification; mechanism

(This special issue belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)

Value-Added Products from Marine Microalgae

edited by Francisco Omar Holguin and Jurgen E. W. Polle

submission deadline 30 Jun 2025 | Viewed by 285 | Submission Open

Keywords: value added; pigments; vitamins; lipids; polysaccharides; cosmeceutical; anticancer; antioxidant; antimicrobial; bioactive; biotechnology; nutritional supplements

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

A ‘One-Health Focus’ on Natural Marine Toxins

edited by Zhijun Tan and Jixing Peng

submission deadline 1 Jul 2025 | Viewed by 105 | Submission Open

Keywords: harmful algae blooming; risk assessment; toxicity; oxidative stress responses; multi-omics analysis; immune defense response; bivalve

(This special issue belongs to the Section Marine Toxins)

Emerging Toxins Accumulation in Shellfish

edited by

Sandra Lage

submission deadline 15 Jul 2025 | 8 articles | Viewed by 19871 | Submission Open

Keywords: spirolides; yessotoxins; pectenotoxins; palytoxins; tetrodotoxins; ciguatoxins; saxitoxins; BMAA; occurrence data; seafood safety; harmful algal blooms

(This special issue belongs to the Section Marine Toxins)

Marine Drug Research in Italy

edited by

Stella Maria Cascioferro

submission deadline 15 Jul 2025 | 7 articles | Viewed by 14915 | Submission Open

Keywords: marine natural products; synthesis; structure elucidation; proteomics; glycomics; lipidomics; biotechnology

Marine Anti-Biofilm Compounds from Natural to Synthetic Compounds

edited by

Marie-Lise Bourguet-Kondracki

Jean Michel Brunel

Melissa M. Cadelis

and

Brent R. Copp

submission deadline 15 Jul 2025 | 3 articles | Viewed by 9542 | Submission Open

Keywords: marine natural or synthetic products; antibiofilm; antimicrobial; antibiotics; antifouling; quorum sensing; EPS matrix

(This special issue belongs to the Section Marine Pharmacology)

Structural Diversity in Marine Natural Products

edited by

Bae Munhyung

and

Jae-hyuk Jang

submission deadline 15 Jul 2025 | 3 articles | Viewed by 2610 | Submission Open

Keywords: marine natural products; marine biotechnology; bioactive secondary metabolites; structural diversity; isolation and structure elucidation; biosynthesis; drug candidates

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

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