Advances in Secondary Metabolites from Mangrove Holobiont

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Chemoecology for Drug Discovery".

Deadline for manuscript submissions: 1 November 2025 | Viewed by 44

Special Issue Editors


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Guest Editor
Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China
Interests: marine natural product chemistry; drug leads; pharmacological mechanism; marine microorganisms; biotransformation
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Guest Editor
Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China
Interests: marine natural products; natural product synthesis; active skeleton synthesis methodology; pharmacological mechanism

Special Issue Information

Dear Colleagues,                

Mangroves are complex and unique ecosystems, and their holobiont includes the close connections among various organisms, such as mangrove plants, microorganisms (such as fungi, bacteria, etc.), and animals. Through the study of secondary metabolites from mangrove holobionts, it is possible to gain an in-depth understanding of the ways in which these symbionts communicate and interact through chemical signal molecules. The natural products in mangrove holobionts often have unique chemical structures and diverse biological activities. Many compounds isolated from mangrove-related microorganisms have been found to have pharmacological activities, such as antibacterial, antiviral, anti-tumor, and anti-inflammatory, providing rich lead compound resources for the research and development of new drugs. These natural products have special biosynthetic mechanisms that are different from those of terrestrial organisms. Studying their synthetic pathways can discover new chemical reactions, enzymatic catalytic mechanisms, etc., providing new ideas for the development of disciplines, such as bio-organic chemistry and synthetic biology and inspiring researchers to synthesize complex compounds with application value through bionic synthesis and other means.

Prof. Dr. Xuefeng Zhou
Dr. Huaming Tao
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • mangrove holobiont
  • natural products
  • pharmacological activities
  • biosynthetic mechanisms
  • symbionts communicate
  • lead compound

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