Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Anesthesia and Critical Care
edited by
submission deadline 26 Jun 2026 | 5 articles | Viewed by 6338 | Submission Open
Keywords: anesthesia; intensive care training; updates in anesthesia; machine learning
(This special issue belongs to the Section Medical Research)
Advances in Dryland Agriculture Science
edited by and Hangyu Dong
submission deadline 26 Jun 2026 | 3 articles | Viewed by 3948 | Submission Open
Keywords: dry farming; climate smart agriculture; soil and water protection; conservation tillage; intercropping; crop rotation; saving irrigation
(This special issue belongs to the Section Plant Science)
Feature Papers in Medical Research: 4th Edition
edited by
submission deadline 26 Jun 2026 | Viewed by 311 | Submission Open
Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research
(This special issue belongs to the Section Medical Research)
Innovations in Thoracic Medicine: Advancements and Challenges—2nd Edition
edited by Paolo Scanagatta
submission deadline 26 Jun 2026 | Viewed by 80 | Submission Open
Keywords: thoracic medicine; lung cancer; artificial intelligence (AI); minimally invasive intervention; thoracic anesthesia; clinical innovation; technological advances
(This special issue belongs to the Section Medical Research)
Application of Mass Spectrometry-Based Multi-Omics in Biomedical Research submission deadline 26 Jun 2026 | Viewed by 77 | Submission Open
Keywords: mass spectrometry; multi-omics; proteomics; metabolomics; lipidomics; mass spectrometry imaging (MSI); biomarker discovery; translational research
(This special issue belongs to the Section Medical Research)
Advanced Technologies and Clinical Practice of Cancer Radiotherapy
edited by
submission deadline 26 Jun 2026 | Viewed by 44 | Submission Open
Keywords: proton therapy; BNCT; in vivo dose verification in radiotherapy; accelerators for radiation therapy; simulation of radiotherapies
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Harnessing Mitochondrial Rewiring for Cancer Therapy: Novel Strategies in the Era of Precision Medicine
edited by and Maria Sideridou
submission deadline 26 Jun 2026 | Viewed by 36 | Submission Open
Keywords: Oxidative stress; Metabolic rewiring; Carcinogenesis; DNA repair; Cancer therapy; Heteroplasmy
(This special issue belongs to the Section Physiology and Pathology)
Recent Advances in Physiotherapy for Musculoskeletal submission deadline 30 Jun 2026 | 6 articles | Viewed by 15329 | Submission Open
Keywords: musculoskeletal rehabilitation; emerging technologies; virtual reality; artificial intelligence; inflammatory genetics; physiotherapy; sports medicine; functional recovery
(This special issue belongs to the Section Physiology and Pathology)
The Emerging Role of Microbiota in Health and Diseases
edited by Edyta Juszczuk-Kubiak and Katarzyna Góralska
submission deadline 30 Jun 2026 | 6 articles | Viewed by 12512 | Submission Open
Keywords: microbiota; eubiosis; dysbiosis; microbiota– host interaction; microbiota– gut– brain axis; microbiome; bacteria– fungi interactions; microbiota modification; holobiont; cross-feeding; microbiota related diseases; microbiota functions
(This special issue belongs to the Section Microbiology)
Current Advances in Lung Cancer Diagnosis and Treatment
edited by , Daesik Yang and
submission deadline 30 Jun 2026 | 4 articles | Viewed by 8890 | Submission Open
Keywords: lung cancer; underlying lung disease; radiotherapy; systemic therapy; survival outcomes; complication; biomarkers
(This special issue belongs to the Section Medical Research)
Update on Microalgae Metabolites submission deadline 30 Jun 2026 | 2 articles | Viewed by 3667 | Submission Open
Keywords: biosynthesis; culture conditions; bioactive compounds; biological activity; biorefinery; proteins; peptides; antifreeze proteins; enzymes; carbohydrates; exocellular polysaccharides; carbohydrate-binding proteins; lipids; fatty acids; chlorophylls; carotenoids; phycobiliproteins; vitamins; minerals; trace elements; sterols; secondary metabolites; downstream processing; purification; safety; regulatory issues; clinical tests
(This special issue belongs to the Section Microbiology)
Sialic Acid and Sialic Acid Derivatives in Biomedicine
edited by and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3391 | Submission Open
Keywords: sialic acid; drug development; sialidase inhibitors; sialylation; sialidase; biomarker
(This special issue belongs to the Section Physiology and Pathology)
Musculoskeletal Imaging: Innovations in Diagnostics and Interventional Therapies
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3329 | Submission Open
Keywords: magnetic resonance imaging; bone and bones; computed tomography; sarcoma; interventional radiology
(This special issue belongs to the Section Medical Research)
Microalgae and Their Biotechnological Potential
edited by , Yi Xin and Yuanxue Liang
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3078 | Submission Open
Keywords: microalgae; biofuels; bioproducts; lipid metabolism; synthetic biology; system engineering
(This special issue belongs to the Section Microbiology)
Latest Updates on Clinical Microbiology and Antimicrobial Resistant Infection
edited by Jun Sung Hong
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2995 | Submission Open
Keywords: enterobacteriaceae; antimicrobial resistance; infection; health
(This special issue belongs to the Section Microbiology)
Advances in Livestock Breeding, Nutrition and Metabolism
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2312 | Submission Open
Keywords: genetic selection; livestock breeding; genome editing; animal nutrition; precision feeding; nutritional additives; feed conversion; metabolism; animal health; sustainability
(This special issue belongs to the Section Animal Science)
Pathological and Clinical Updates on Eye Diseases
edited by Pier Luigi Surico and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 2310 | Submission Open
Keywords: ophthalmology; eye diseases; gene therapy; ocular surface; ocular immunology; cornea
(This special issue belongs to the Section Medical Research)
Move to Thrive: Pioneering Health and Resilience Through Physical Activity submission deadline 30 Jun 2026 | 1 articles | Viewed by 2290 | Submission Open
Keywords: physical activity; inflammation modulation; chronic disease prevention; immune system adaptation; biomechanics; rehabilitation strategies; sports medicine; aging and physical activity; disability and movement; environmental and regional influences on exercise
(This special issue belongs to the Section Physiology and Pathology)
Helicobacter pylori: 2nd Edition
edited by and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2110 | Submission Open
Keywords: H. pylori; cancers; antioxidative process; diagnostic methods
(This special issue belongs to the Section Microbiology)
Role of Machine and Deep Learning in Drug Screening
edited by and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1607 | Submission Open
Keywords: machine learning in drug screening; deep learning in drug discovery; virtual screening; molecular docking and dynamics; personalized medicine
(This special issue belongs to the Section Pharmaceutical Science)
Advances in the Glyoxalase Pathway: Implications for Oxidative Stress Management in Cancer Therapy and in Age-Related Disease submission deadline 30 Jun 2026 | 1 articles | Viewed by 1571 | Submission Open
Keywords: glyoxalase system; methylglyoxal; advanced glycation end-products; dicarbonyl stress; oxidative stress; age-related disease; cancer
(This special issue belongs to the Section Physiology and Pathology)
Research on Gastrointestinal Cancer and Nutritional Health
edited by , Adam Mylonakis and Dimitrios Tsapralis
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1444 | Submission Open
Keywords: dietary patterns; gastrointestinal cancer; clinical nutrition; nutritional status; nutritional assessment; metabolism; gastric cancer; esophageal cancer; pancreatic cancer; colorectal cancer
(This special issue belongs to the Section Medical Research)
Channel Proteins and Transporters in Human Health and Disease submission deadline 30 Jun 2026 | Viewed by 1067 | Submission Open
Keywords: channel proteins; transporters; ion channel
(This special issue belongs to the Section Proteins and Proteomics)
Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders
edited by Arkadiusz Komorowski
submission deadline 30 Jun 2026 | 1 articles | Viewed by 683 | Submission Open
Keywords: psychiatry; neuroimaging; forensic psychiatry; fMRI; PET; EEG; addiction; substance use disorders (SUD); psychotherapy; treatment-resistant depression (TRD); attention deficit hyperactivity disorder (ADHD)
(This special issue belongs to the Section Physiology and Pathology)
Cutting-Edge Research in Rhinology and Allergy: Unraveling Disease Mechanisms and Treatment Innovations
edited by Min-Seok Rha
submission deadline 30 Jun 2026 | 1 articles | Viewed by 601 | Submission Open
Keywords: rhinology; allergy; chronic rhinosinusitis; allergic rhinitis; asthma; precision medicine; clinical immunology; immunopathology; therapeutic innovation
Perspectives on Nutrition and Livestock Health
edited by Liuting Wu, Yan Wang and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 574 | Submission Open
Keywords: nutrition; animal health; animal reproductive; animal welfare; gut microbiome
(This special issue belongs to the Section Animal Science)
Applications of Dermatoscopy in Skin Diseases: 2nd Edition submission deadline 30 Jun 2026 | 1 articles | Viewed by 562 | Submission Open
Keywords: melanoma; skin cancer; inflammoscopy; trichoscopy; ultraviolet reflectance dermatoscopy; skin of color; basal cell carcinoma; squamous cell carcinoma; nevus; digital dermoscopy
(This special issue belongs to the Section Medical Research)
Vector-Borne Diseases and One Health
edited by , Shayenne Silva and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 500 | Submission Open
Keywords: vector-borne diseases; One Health; malaria; dengue; Zika; chikungunya; yellow fever; West Nile virus; Lyme disease; leishmaniasis; Chagas
(This special issue belongs to the Section Animal Science)
Cranial Base Tumors: Pathogenesis, Diagnosis, and Treatments
edited by and Marcin Szymański
submission deadline 30 Jun 2026 | 1 articles | Viewed by 455 | Submission Open
Keywords: skull base tumors; neuro-oncology; endoscopic surgery; cranial nerve preservation; AI-assisted diagnostics; multidisciplinary management
(This special issue belongs to the Section Medical Research)
New Advances in the Treatment and Assessment of Temporomandibular Joint Disorders submission deadline 30 Jun 2026 | Viewed by 341 | Submission Open
Keywords: orofacial dysfunction; multifactorial etiology; advanced diagnostic technologies; biomechanical modeling of TMJ; novel imaging techniques; inflammatory and degenerative changes; interdisciplinary management; conservative therapy approaches; occlusal concepts; splint therapy design; physical therapy regimens; long-term implant treatment outcomes; personalized treatment strategies
(This special issue belongs to the Section Medical Research)
Autoimmune Disorders: From Pathophysiology to Therapeutics
edited by and Chiara Mura
submission deadline 30 Jun 2026 | Viewed by 292 | Submission Open
Keywords: autoimmunity; autoimmune diseases; polyglandular autoimmune syndromes; thyroid autoimmune disease; type 1 diabetes
(This special issue belongs to the Section Physiology and Pathology)
Post-Concussion Syndrome and Functional Neurological Disorder submission deadline 30 Jun 2026 | Viewed by 194 | Submission Open
Keywords: post-concussion syndrome; functional neurological disorder; mild traumatic brain injury; cognitive dysfunction  ; neuroimaging; biomarkers; neurorehabilitation
(This special issue belongs to the Section Medical Research)
Placental Spectrum Disorders and Gynecological Oncology
edited by Gianluca Raffaello Damiani
submission deadline 30 Jun 2026 | Viewed by 166 | Submission Open
Keywords: placenta; trophoblastic tumor; mola; tumors; bleeding
(This special issue belongs to the Section Medical Research)
Advances in Bioorganic and Medicinal Chemistry
edited by Sahar Kandil
submission deadline 30 Jun 2026 | Viewed by 151 | Submission Open
Keywords: medicinal chemistry; drug discovery; biological chemistry; therapeutic targets; therapeutic agents; treatment of diseases; new therapeutic strategies
“Out-of-the-Organics-Box” Reflections On and Scenarios for Life’s Emergence
edited by
submission deadline 30 Jun 2026 | Viewed by 123 | Submission Open
Keywords: emergence of life; thermodynamics; bioenergetics; information theory; early metabolism; metal ions in biochemistry
(This special issue belongs to the Section Origin of Life)
Transplant Medicine: Updates and Current Challenges
edited by Phillipe Abreu
submission deadline 30 Jun 2026 | Viewed by 119 | Submission Open
Keywords: robotic transplantation; organ transplants; transplant oncology
(This special issue belongs to the Section Medical Research)
Sleep-Disordered Breathing: Key Pathophysiological Mechanisms and Their Clinical Implications
edited by
submission deadline 30 Jun 2026 | Viewed by 105 | Submission Open
Keywords: sleep-disordered breathing; sleep fragmentation; inflammation; cardiovascular disease; insulin resistance
(This special issue belongs to the Section Physiology and Pathology)
Advances and Challenges in Urothelial and Prostate Cancer: Toward Precision Urologic Oncology
edited by Sashi S. Kommu
submission deadline 30 Jun 2026 | Viewed by 101 | Submission Open
Keywords: urothelial carcinoma; prostate cancer; immunotherapy; genomics and biomarkers; precision imaging (PSMA PET; mpMRI); targeted therapies (PARP; FGFR; DDR); focal therapy and theranostics; tumour microenvironment; quality of life and survivorship; health disparities in cancer care; artificial intelligence
(This special issue belongs to the Section Medical Research)
Physical Rehabilitation for Musculoskeletal Disorders: 2nd Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 100 | Submission Open
Keywords: physical rehabilitation; musculoskeletal disorders; pain management; range of motion; muscle strengthening; mobility enhancement; physical therapy; manual therapy; AI in rehabilitation
(This special issue belongs to the Section Medical Research)
Neural Mechanisms of Brain–Computer Interfaces
edited by
submission deadline 30 Jun 2026 | Viewed by 78 | Submission Open
Keywords: brain– machine interfaces; neurophysiology; somatosensory cortex; motor cortex
(This special issue belongs to the Section Physiology and Pathology)
Mechanisms and Modulation of Pain: From Ion Channels to Translational Therapeutics
edited by Álvaro Yogi
submission deadline 30 Jun 2026 | Viewed by 76 | Submission Open
Keywords: pain; mechanisms; signaling pathways; ion channels; therapeutic targets; neuropathic pain; inflammatory pain; pre-clinical models
(This special issue belongs to the Section Pharmaceutical Science)
Drug Safety and Outcomes in Respiratory and Critical Care Medicine
edited by
submission deadline 30 Jun 2026 | Viewed by 71 | Submission Open
Keywords: drug safety; adverse drug reactions; pharmacovigilance; critical care medicine; respiratory diseases; clinical outcomes; intensive care pharmacotherapy; drug– drug interactions
(This special issue belongs to the Section Pharmaceutical Science)
Neurodegeneration Across Mechanisms, Epidemiology, and Emerging Therapies: Inflammation, Metabolism, Aging, and Neuromodulation
edited by Julian Benito Leon
submission deadline 30 Jun 2026 | Viewed by 60 | Submission Open
Keywords: neurodegeneration; neuroinflammation; metabolic dysfunction; aging and inflammaging; epidemiology; biomarkers; neuromodulation; transcranial magnetic stimulation (TMS)
(This special issue belongs to the Section Medical Research)
Extracellular Vesicles: Biology, Mechanisms, and Therapies for Cerebrovascular Disorders
edited by Jinju Wang
submission deadline 30 Jun 2026 | Viewed by 56 | Submission Open
Keywords: extracellular vesicles; cerebrovascular disorders; dementia; extracellular vesicle-based therapy
(This special issue belongs to the Section Physiology and Pathology)
Comprehensive Treatment and Precision Medicine Strategies for Heart Disease
edited by Serge Sicouri
submission deadline 30 Jun 2026 | Viewed by 51 | Submission Open
Keywords: precision medicine; artificial intelligence; risk stratification; machine learning; translational research; cardiovascular outcomes
(This special issue belongs to the Section Medical Research)
Rewiring Bacterial Communication: Extracellular Vesicles and Microbial Signals Across Host Interfaces
edited by Sara Carloni
submission deadline 30 Jun 2026 | Viewed by 44 | Submission Open
Keywords: bacterial extracellular vesicles (bEVs); host– microbe communication; microbiota dynamics; immune modulation; translational applications
(This special issue belongs to the Section Microbiology)
New Insights into Diagnosis and Therapeutic Strategies for Chronic Liver Diseases
edited by
submission deadline 20 Jul 2026 | 5 articles | Viewed by 9517 | Submission Open
Keywords: chronic liver disease; metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); drug-induced liver injury (DILI); hepatocellular carcinoma; biomarkers of liver fibrosis; imaging of liver fibrosis; CEUS; novel therapeutic strategies for CLDs
(This special issue belongs to the Section Medical Research)
Herbal Extracts in Skin Health and Disease
edited by
submission deadline 20 Jul 2026 | Viewed by 123 | Submission Open
Keywords: herbal extracts; natural products; skin disorders; skin care
(This special issue belongs to the Section Pharmaceutical Science)
Emerging Knowledge on Human Immunodeficiency Virus submission deadline 22 Jul 2026 | 3 articles | Viewed by 23532 | Submission Open
Keywords: HIV; antiretroviral treatment; long-acting ART; pre-exposure prophylaxis; HIV surveillance; antiretroviral resistance; primary resistance; HIV epidemiology; special populations; cascade of care; HIV diagnosis
(This special issue belongs to the Section Medical Research)
Genetics, Breeding, and Reproduction of Cattle submission deadline 24 Jul 2026 | Viewed by 242 | Submission Open
Keywords: cattle; genetic selection; reproductive physiology and technology
(This special issue belongs to the Section Animal Science)
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