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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Translational Neuro-Oncology: Molecular Insights, Bioinformatics, and Technological Innovations

edited by Felix Mircea Brehar

submission deadline 20 Sep 2026 | Viewed by 78 | Submission Open

Keywords: translational neuro-oncology; central nervous system tumors; molecular and cellular mechanisms; multi-omics and biomarkers; bioinformatics and systems biology; artificial intelligence in medicine; radiomics and radiogenomics; precision neurosurgery; experimental and clinical research; therapeutic innovation in neuro-oncology

(This special issue belongs to the Section Physiology and Pathology)

Imaging and Analysis of Microbial Motility: From Single Cells to Communities

edited by

Jay Nadeau

submission deadline 20 Sep 2026 | Viewed by 26 | Submission Open

Keywords: motility; cell tracking; biofilm; swimming; swarming; Archaea; flagella

(This special issue belongs to the Section Microbiology)

Mucosal Immunity and Immune Memory: The New Frontier in Vaccination and Immunopathology

edited by

Lalit Batra

submission deadline 20 Sep 2026 | Viewed by 17 | Submission Open

Keywords: mucosal immunity; hybrid immunity; next-generation vaccines; artificial intelligence; neo-adjuvants; clinical trial; case studies

(This special issue belongs to the Section Medical Research)

Prebiotic RNA: From Autocatalysis and Chirality to Functional Evolution

edited by

Paul Higgs

submission deadline 20 Sep 2026 | Viewed by 3 | Submission Open

Keywords: RNA; origin of life; replication; autocatalysis; chirality; ribozymes; metabolism

(This special issue belongs to the Section Origin of Life)

Molecular Underpinnings of Cancer: Pathways to Targeted Therapy

edited by

Rahul Shivahare

and

Joon-Yong Chung

submission deadline 30 Sep 2026 | Viewed by 103 | Submission Open

Keywords: signaling pathways; tumor microenvironment; cancer metabolism; biomarkers; drug resistance; precision medicine; targeted therapy

(This special issue belongs to the Section Medical Research)

Neurorehabilitation: Technology-Driven Recovery and Functional Rewiring

edited by

Simone Carozzo

submission deadline 30 Sep 2026 | Viewed by 99 | Submission Open

Keywords: cognitive-motor recovery; neuroplasticity; multidimensional assessment; post-stroke rehabilitation

(This special issue belongs to the Section Medical Research)

Women's Health and Well-Being: A Focus on Obstetrics and Gynecologic Medicine

edited by Luca Roncati

submission deadline 30 Sep 2026 | Viewed by 93 | Submission Open

Keywords: women’ s health; gynecology; gynecopathology; preventive gynecological oncology; senology; breast cancer; cervical cancer; sexually transmitted infections; human papillomavirus; autoimmune diseases

(This special issue belongs to the Section Medical Research)

Biomarkers in Ischemic Stroke: From Discovery to Clinical Applications

edited by Hock-Kean Liew

submission deadline 30 Sep 2026 | Viewed by 90 | Submission Open

Keywords: ischemic stroke; biomarkers; neuroinflammation; oxidative stress; excitotoxicity; thrombolysis; mechanical thrombectomy; blood– brain barrier; neuroprotection; precision medicine

(This special issue belongs to the Section Medical Research)

Cognitive and Imaging Mechanisms in Neurological Disorders

edited by Foteini Christidi,

Anna Tsiakiri

and

Efstratios Karavasilis

submission deadline 30 Sep 2026 | Viewed by 83 | Submission Open

Keywords: neurological disorders; cognitive dysfunction; neuropsychological assessment; neuroimaging; structural MRI; functional MRI; multimodal neuroimaing; biomarkers; machine learning in neurology; neurorehabilitation

(This special issue belongs to the Section Medical Research)

Advanced Optical Imaging for Tissue and Tumour Characterization

edited by

Ana Batista

and Ana Teresa A. Amaral

submission deadline 30 Sep 2026 | Viewed by 61 | Submission Open

Keywords: optical imaging; label-free imaging; functional imaging; multimodal imaging; tissue characterization; tumour microenvironment; tumour heterogeneity; extracellular matrix; therapeutic monitoring

(This special issue belongs to the Section Medical Research)

Ocular Diseases: Mechanisms, Diagnostics, and Emerging Therapeutic Strategies

edited by Joanna Dolar-Szczasny

submission deadline 30 Sep 2026 | Viewed by 56 | Submission Open

Keywords: molecular mechanisms of eye disease; oxidative stress and inflammation; neurodegeneration in vision; ocular biomarkers; pharmacological therapies; gene therapy; stem cell and regenerative approaches; precision/personalized ophthalmology

(This special issue belongs to the Section Medical Research)

The Oral-Systemic Link in Chronic Mucosal Diseases

edited by

Ioanina Parlatescu

submission deadline 30 Sep 2026 | Viewed by 35 | Submission Open

Keywords: oral diseases; general diseases; biomarkers

(This special issue belongs to the Section Medical Research)

Synthetic Biology and Biotechnology Application of Algae

edited by Fantao Kong and

Chaogang Wang

submission deadline 30 Sep 2026 | Viewed by 4 | Submission Open

Keywords: synthetic biology; algal biotechnology; metabolic engineering; biofuels; carbon capture; high-value products; genetic tools; bioremediation

(This special issue belongs to the Section Synthetic Biology and Systems Biology)

Pathology, Diagnosis, and Treatments of Airway Diseases

edited by

Laura Bergantini

and

Tommaso Pianigiani

submission deadline 1 Oct 2026 | 1 articles | Viewed by 793 | Submission Open

Keywords: airway diseases; COPD; asthma; cystic fibrosis; bronchiectasis; biomarkers; biologics; targeted; immunology; pathogenesis

(This special issue belongs to the Section Medical Research)

Innovations in Critical Care and Anesthesiology

edited by

Luigi La Via

submission deadline 2 Oct 2026 | 1 articles | Viewed by 398 | Submission Open

Keywords: artificial intelligence in ICU; point-of-care monitoring; enhanced recovery protocols; precision anesthesia; mechanical ventilation; organ support systems; perioperative medicine; critical care innovations

(This special issue belongs to the Section Medical Research)

Novel Liquid Biopsy Biomarkers and Multi-Omic Integration in Metabolic Diseases

edited by

Makrina Karaglani

submission deadline 20 Oct 2026 | 1 articles | Viewed by 4079 | Submission Open

Keywords: liquid biopsy; metabolic diseases; cell-free DNA; extracellular vesicles; multi-omics; biomarkers; epigenetics; machine learning; NAFLD

(This special issue belongs to the Section Medical Research)

Artificial Intelligence in Head and Neck Cancer Radiotherapy and Imaging

edited by Elias Liolis

submission deadline 30 Oct 2026 | Viewed by 49 | Submission Open

Keywords: head and neck cancer; treatment planning; radiotherapy; oral cavity cancer; PET-CT imaging

(This special issue belongs to the Section Medical Research)

Pharmacotherapy in Critical Care: Clinical Insight and Emerging Strategy

edited by

Caterina Aurilio

submission deadline 31 Oct 2026 | Viewed by 96 | Submission Open

Keywords: sepsis; multidrug resistance; extracorporeal treatments; intracranial hypertension; immunomodulation; organ support; precision medicine; intensive care pharmacology

(This special issue belongs to the Section Medical Research)

Precision Approaches in Solid Tumor Oncology: From Molecular Pathways to Therapy Response

edited by

Cristina Díaz del Arco

and Luís Ortega-Medina

submission deadline 31 Oct 2026 | Viewed by 47 | Submission Open

Keywords: biomarkers; histology; immunohistochemistry; solid tumors; precision oncology; therapy response

(This special issue belongs to the Section Medical Research)

The Roles and Regulation of RECK in Cell Behavior, Animal Development, and Diseases

edited by

Makoto Noda

and

David B. Alexander

submission deadline 31 Oct 2026 | Viewed by 4 | Submission Open

Keywords: cancer; metastasis; cell migration; angiogenesis; neurogenesis; extracellular matrix; disease models

(This special issue belongs to the Section Physiology and Pathology)

Otolaryngology and Sleep Medicine: From Precision Diagnosis to Advanced Therapeutics

edited by

Antonino Maniaci

submission deadline 28 Nov 2026 | Viewed by 43 | Submission Open

Keywords: sleep-disordered breathing; otolaryngology; sleep medicine; pulmonology; neurology

(This special issue belongs to the Section Medical Research)

Global Health in a Changing Climate: Interdisciplinary Perspectives on Human Well-Being

edited by Giuseppe Marano,

Marianna Mazza

, Gianandrea Traversi,

Eleonora Gaetani

and Esmeralda Capristo

submission deadline 30 Nov 2026 | Viewed by 50 | Submission Open

Keywords: climate change; global health; mental health; physical health; lifestyle interventions; cross-disciplinary research

(This special issue belongs to the Section Medical Research)

Advances in Diagnostic Management of Cardiovascular Diseases

edited by Carlo Gaudio,

Luigi Spadafora

and

Marco Bernardi

submission deadline 30 Nov 2026 | Viewed by 41 | Submission Open

Keywords: cardiovascular diagnostics; advanced imaging; biomarkers; artificial intelligence; risk stratification

(This special issue belongs to the Section Medical Research)

Advances in Computational and Spatial Pathology

edited by

Taobo Hu

submission deadline 20 Dec 2026 | Viewed by 32 | Submission Open

Keywords: computational pathology; spatial pathology; spatial transcriptomics; spatial proteomics; digital pathology; whole-slide imaging; deep learning; machine learning; tumor microenvironment; tissue architecture; multiplexed imaging; biomarker discovery; multimodal data integration

(This special issue belongs to the Section Physiology and Pathology)

The 15th Anniversary of Life—New Trends in Animal Health Science

edited by

Einar Ringø

submission deadline 31 Dec 2026 | 1 articles | Viewed by 481 | Submission Open

Keywords: animal health science; animal disease; veterinary; animal nutrition; genetics; breeding and reproduction; One Health

(This special issue belongs to the Section Animal Science)

The Microbiome and Dysbiosis in Various Pathologies

edited by

Roxana Liana Lucaciu

Lucia Maria Procopciuc

and

Adriana Corina Hangan

submission deadline 31 Dec 2026 | Viewed by 94 | Submission Open

Keywords: metabolic diseases (obesity; type 2 diabetes; insulin resistance; metabolic syndrome; etc.); cardiovascular diseases (atherosclerosis; hypertension; etc.); dermatological diseases (acne; eczema; psoriasis; rosacea); autoimmune and inflammatory diseases (rheumatoid arthritis; systemic lupus erythematosus; multiple sclerosis; Hashimoto’ s thyroiditis; etc.); digestive disorders (irritable bowel syndrome; inflammatory bowel disease: Crohn’ s disease and ulcerative colitis; celiac disease; lactose intolerance and other food intolerances; gastritis; helicobacter pylori infections; etc.); neurological and psychiatric disorders (Parkinson’ s and Alzheimer’ s disease; depression; anxiety; autism); recurrent infections and low immunity; cancer (colorectal; gastric; esophageal; hepatic; pancreatic; breast; pulmonary; etc.); biochemical; genetic and epigenetic biomarkers; computational analysis

(This special issue belongs to the Section Microbiology)

Pathogenesis, Biomarkers, and Treatments of Skin Diseases

edited by

Annunziata Raimondo

submission deadline 31 Dec 2026 | Viewed by 81 | Submission Open

Keywords: immune-pathogenesis; biomarkers; skin

(This special issue belongs to the Section Medical Research)

Cell Regulation and Function

edited by

Tada-aki Kudo

submission deadline 31 Dec 2026 | Viewed by 55 | Submission Open

Keywords: cellular regulation; signal transduction; cell differentiation and apoptosis; systems biology and omicsdisease mechanisms

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Physical Activity, Inflammation, and Adipocytokines: Molecular Responses in Health and Disease

edited by

Marta Mallardo

and Aurora Daniele

submission deadline 31 Dec 2026 | Viewed by 52 | Submission Open

Keywords: physical activity; inflammation; inflammatory biomarkers; adipocytokines; exercise physiology; healthy life-style; metabolic disorders; cancer; athletes

(This special issue belongs to the Section Physiology and Pathology)

Targeting Myeloid Cells in the Tumor Microenvironment

edited by Tatiana I. Novobrantseva, Igor Feldman and Siamon Gordon

submission deadline 31 Dec 2026 | Viewed by 27 | Submission Open

Keywords: macrophage; tolerance; repolarization; TME; cancer; immuno-therapy therapeutics immunity

(This special issue belongs to the Section Medical Research)

Ophthalmologic Diseases: From Molecules and Molecular Mechanisms to Therapeutics

edited by

Soo-Young Kim

and

Dong Hui Lim

submission deadline 30 Jun 2027 | Viewed by 78 | Submission Open

Keywords: retinal disease; corneal disease; genetic diseases; inflammatory diseases; ocular diseases; ocular drug development

(This special issue belongs to the Section Physiology and Pathology)

Displaying special issue 451-500 on page 10 of 10.

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