Physical Activity, Inflammation, and Adipocytokines: Molecular Responses in Health and Disease
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 1483
Special Issue Editors
2. CEINGE-Biotecnologie Avanzate Scarl “Franco Salvatore”, Via G. Salvatore 486, 80145 Napoli, Italy
Interests: adipokines; adipose tissue; inflammatory response; physical activity; exercise; metabolic disease; athletes; cancer
2. CEINGE-Biotecnologie Avanzate Scarl “Franco Salvatore”, Via G. Salvatore 486, 80145 Napoli, Italy
Interests: adipokines; adipose tissue; diet; nutrition; physical activity; metabolic disease; cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
You are kindly invited to submit contributions to the upcoming Special Issue entitled “Physical Activity, Inflammation, and Adipocytokines: Molecular Responses in Health and Disease”.
Chronic low-grade inflammation has been identified as a major contributor to the global burden of non-communicable diseases, including obesity, metabolic syndrome, type 2 diabetes, cardiovascular disorders, and several cancers. Sedentary lifestyles further increase the prevalence of these conditions, emphasizing the need for effective strategies to promote health and prevent disease. Physical activity is well known as a non-pharmacological tool capable of influencing systemic inflammation, metabolic regulation, and immune competence, with significant implications for disease prevention, health promotion, and clinical management. Inflammatory biomarkers—such as cytokines, chemokines, and adipocytokines—are involved in the regulation of fundamental biological processes (e.g., energy homeostasis, cellular stress responses) in both physiological and pathological conditions. Regular physical activity modulates several of these biomarkers, thereby promoting an anti-inflammatory environment and improving health outcomes in both healthy individuals and patients affected by chronic disorders. In athletes, physiological exercise stimuli also induce characteristic inflammatory patterns, providing a valuable framework for understanding adaptation, recovery, and performance. The aim of this Special Issue is to provide a comprehensive overview of the recent research on the interplay between physical activity, inflammation, and health outcomes. Contributions addressing molecular mechanisms, biomarker profiling, and translational or clinical implications of exercise-induced inflammatory modulation are particularly welcomed.
Dr. Marta Mallardo
Prof. Dr. Aurora Daniele
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- physical activity
- inflammation
- inflammatory biomarkers
- adipocytokines
- exercise physiology
- healthy life-style
- metabolic disorders
- cancer
- athletes
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