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Life
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The 15th Anniversary of Life—New Trends in Animal Health...
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The 15th Anniversary of Life—New Trends in Animal Health Science

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Animal Science".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 5356

Special Issue Editor

Prof. Dr. Einar Ringø

E-Mail Website
Guest Editor
Faculty of Bioscience, Fisheries and Economics, Norwegian College of Fishery Science, UiT The Arctic University of Norway, 9019 Tromsø, Norway
Interests: fish; microbial ecology; lipid nutrition; electron microscopy; gut microbiota
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

2026 will mark the 15th anniversary of Life (ISSN: 2075-1729). During the past 15 years, the Section "Animal Science" has published papers on many scientific advancements. We thank our authors, reviewers, Editorial Board Members, and readers for their invaluable support, which made reaching this milestone possible.

To commemorate this anniversary, we are launching a Special Issue dedicated to Animal Health Science. This collection will highlight the progress achieved in the past decades, current knowledge, and the emerging challenges and opportunities that lie ahead.

We invite contributions that span the full spectrum of animal health, including but not limited to the following topics:

  • Animal disease prevention and management;
  • Veterinary medicine;
  • Animal nutrition and sustainable livestock management;
  • Genetics, breeding and reproduction;
  • Genomics, immunology, and biotechnology in animal health research;
  • One Health perspectives linking animal, human, and environmental health;

We look forward to receiving your contributions and to shaping the next chapter of the Section "Animal Science" together.

Prof. Dr. Einar Ringø
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • animal health science
  • animal disease
  • veterinary
  • animal nutrition
  • genetics, breeding and reproduction
  • One Health

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (4 papers)

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Research

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25 pages, 2289 KB  
Article
Development and Testing of an Aquaculture Environmental Control System Based on Behavioral Stress Responses
by Bin Wang, Hang Yang, Hanping Mao and Qiang Shi
Life 2025, 15(12), 1809; https://doi.org/10.3390/life15121809 - 25 Nov 2025
Cited by 2 | Viewed by 869
Abstract
This study addresses key challenges in intensive aquaculture, such as passive environmental control, high energy consumption, and neglected fish stress, through the development of a multi-objective environmental regulation system for crucian carp utilizing behavioral stress feedback. It combines YOLOv8s-FasterNet for behavior recognition, a [...] Read more.
This study addresses key challenges in intensive aquaculture, such as passive environmental control, high energy consumption, and neglected fish stress, through the development of a multi-objective environmental regulation system for crucian carp utilizing behavioral stress feedback. It combines YOLOv8s-FasterNet for behavior recognition, a specific growth rate model and an energy cost model to form an intelligent decision-making mechanism that maximizes the output–input ratio. In a 25-day experiment, the system showed strong performance. Final body weight and specific growth rate were comparable to the control group. Economically, the system achieved periodic profits that were 8.93, 1.43, and 1.03 times greater than those of traditional threshold control at external temperatures of 2 °C, 8 °C, and 14 °C, respectively, demonstrating significant energy savings. In terms of animal welfare, principal component analysis confirmed significantly lower stress-induced damage in the experimental group, with a comprehensive score (−0.036) closer to the initial healthy group (0.223) versus the control group (−0.348). These results indicate that the system successfully optimized both economic efficiency and fish health, providing a viable solution for intelligent aquaculture management. Full article
(This article belongs to the Special Issue The 15th Anniversary of Life—New Trends in Animal Health Science)
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Review

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28 pages, 1929 KB  
Review
Radiation in Veterinary Practice: Paradigm Shift Toward Precision and Curative Approaches
by Sorin Marian Mârza, Camelia Munteanu, Radu Lăcătuş, Ionel Papuc, Florin Dumitru Bora and Robert Cristian Purdoiu
Life 2026, 16(4), 626; https://doi.org/10.3390/life16040626 - 8 Apr 2026
Viewed by 1509
Abstract
Ionizing radiation therapy has undergone a clear paradigm shift in veterinary oncology and inflammatory disease management, moving from mainly palliative use toward structured, curative treatment programs. This review synthesizes current evidence on key modalities used in veterinary practice, including external beam radiotherapy, brachytherapy, [...] Read more.
Ionizing radiation therapy has undergone a clear paradigm shift in veterinary oncology and inflammatory disease management, moving from mainly palliative use toward structured, curative treatment programs. This review synthesizes current evidence on key modalities used in veterinary practice, including external beam radiotherapy, brachytherapy, systemic targeted radionuclide therapy, stereotactic radiosurgery, stereotactic body radiotherapy, radiosynoviorthesis, and low-dose radiotherapy. Each modality is discussed in relation to its physical and biological basis, major isotopes or beam types, routes of delivery, target species such as dogs, cats, and horses, clinical indications, and global availability. Comparative analysis highlights differences in clinical acceptance, evidence strength, access, and cost. External beam radiotherapy and stereotactic techniques support curative tumor management, whereas radiosynoviorthesis and low-dose radiotherapy are effective for inflammatory and degenerative disorders. Despite ongoing progress, challenges remain in access, dosimetry standardization, and prospective evidence. Companion animals are also emphasized as valuable translational models, guiding future innovation and collaboration internationally. Full article
(This article belongs to the Special Issue The 15th Anniversary of Life—New Trends in Animal Health Science)
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19 pages, 2100 KB  
Review
Nano-Enabled Herbal Remedies for Malaria Treatment: A Review of Recent Advances
by Chang Xu, Arooj Fatima, Mahreen Fatima, Amjad Islam Aqib, Tean Zaheer, Safia Obaidur Rab, Mohd Saeed, Zeeshan Arif and Kun Li
Life 2026, 16(2), 322; https://doi.org/10.3390/life16020322 - 12 Feb 2026
Viewed by 1528
Abstract
Malaria has long been a significant global health concern, listed as a high-priority disease by several global health agencies, despite of several control measures have been put in place. Most widely utilized treatment options for malaria include chloroquine, artemisinin-based combination therapy (ACT), and [...] Read more.
Malaria has long been a significant global health concern, listed as a high-priority disease by several global health agencies, despite of several control measures have been put in place. Most widely utilized treatment options for malaria include chloroquine, artemisinin-based combination therapy (ACT), and quinine. However, challenges, such as drug resistance, misdiagnosis, and limited treatment efficacy remain major concerns. Despite ongoing efforts, the development of an effective malaria vaccine is still debatable. Many existing malaria treatments have drawbacks, such as low water solubility, poor bioavailability, and a rise in drug-resistant parasites owing to their non-judicious use, which contributes to increased malaria cases and fatalities. Nanotechnology presents a promising approach to safer and more effective malaria therapy and control. Nanoparticles offer several advantages over conventional treatments, including high drug-loading capacity, targeted delivery, improved biocompatibility, and reduced toxicity in host cells. Green nanotechnology-based antimalarial therapies have demonstrated potential therapeutic benefits, enhanced safety, and cost-effectiveness compared to traditional treatments, ultimately improving patient compliance and treatment outcomes. In this review paper, we discussed non-conventional breakpoints in the malarial life cycle, traditional herbal remedies for malaria, and nanoparticle-based delivery systems. Additionally, we reviewed the antimalarial effects of herbal nano-formulations, their pharmacological and therapeutic potential, drug-resistant malaria, preventive strategies, vector control using green nanomaterials, and the challenges associated with plant-based nanotechnologies. This review suggests nanotechnology-based therapeutics as promising candidates to treat malaria with significant room for applications and commercialization potential in the longer run. Full article
(This article belongs to the Special Issue The 15th Anniversary of Life—New Trends in Animal Health Science)
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21 pages, 522 KB  
Review
PEDV Structural Proteins with Emphasis on M Protein as an Immunomodulatory Factor in Porcine Innate Immunity
by Jae-Yeon Park and Hye-Mi Lee
Life 2026, 16(1), 58; https://doi.org/10.3390/life16010058 - 30 Dec 2025
Viewed by 922
Abstract
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal pigs, leading to substantial economic loss in the porcine industry. Previous studies have primarily focused on the spike protein because of its role in viral [...] Read more.
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal pigs, leading to substantial economic loss in the porcine industry. Previous studies have primarily focused on the spike protein because of its role in viral entry and induction of neutralizing antibody responses. However, accumulating evidence indicates that other viral components also contribute to host immune modulation and pathogenesis. This review summarizes the current knowledge on PEDV structural proteins, with an emphasis on membrane proteins as regulators of porcine innate immune responses. The molecular characteristics and intracellular localization of membrane proteins were described, and the reported effects on interferon signaling, inflammatory pathways, and cellular stress responses were examined. Findings from related coronaviruses were incorporated to highlight the conserved features and virus-specific differences in membrane protein-mediated host modulation. Available evidence suggests that membrane protein-associated interference with innate immune signaling may contribute to intestinal immune dysregulation and disease severity in neonatal piglets. The implications of these observations on PEDV pathogenesis and intervention strategies are also discussed. By shifting attention from spike-centered frameworks to structural protein-driven host interactions, this review highlights membrane proteins as an underexplored but biologically relevant factor in porcine coronavirus research. Full article
(This article belongs to the Special Issue The 15th Anniversary of Life—New Trends in Animal Health Science)
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